Abstract: The present disclosure relates to aerosol delivery devices, methods of producing such devices, and elements of such devices. In some embodiments, the present disclosure provides devices configured for vaporization of an aerosol precursor composition that is contained in a reservoir and transported to a heating element by a liquid transport element. The liquid transport element may include a porous monolith.

Abstract: The present disclosure relates to an aerosol delivery device. The aerosol delivery device may include a control body with a first connector portion and a cartridge with a second connector portion. The first connector portion and the second connector portion may be configured to releasably engage each other. One of the first connector portion and the second connector portion may include an extension and the other of the first connector portion and the second connector portion may include a receptacle configured to receive the extension. The extension may include contact sections positioned along a longitudinal length thereof. The contact sections may be electrically insulated from one another by at least one spacer and may be configured to form an electrical connection with the receptacle. A related assembly method is also provided.

Abstract: An Erythropoietic Stimulating Agent (ESA) dosing system/method determines patient-specific ESA therapies for patients affected by insufficient hemoglobin production that may benefit from ESA treatment. The ESA dosing system includes a model that represents a process by which red blood cells are produced in humans. The model may include one or more parameters, the values of which are patient-specific. The model takes into account patient-specific historical hemoglobin (Hgb) data and corresponding historical ESA dosage data to estimate the patient-specific values of the model parameters, and determines a target therapeutic dose of the ESA that may maintain the patient's Hgb within a target range.

Abstract: An Erythropoietic Stimulating Agent (ESA) dosing system/method determines patient-specific ESA therapies for patients affected by insufficient hemoglobin production that may benefit from ESA treatment. The ESA dosing system includes a model that represents a process by which red blood cells are produced in humans. The model may include one or more parameters, the values of which are patient-specific. The model takes into account patient-specific historical hemoglobin (Hgb) data and corresponding historical ESA dosage data to estimate the patient-specific values of the model parameters, and determines a target therapeutic dose of the ESA that may maintain the patient's Hgb within a target range.

Abstract: An Erythropoietic Stimulating Agent (ESA) dosing system/method determines patient-specific ESA therapies for patients affected by insufficient hemoglobin production that may benefit from ESA treatment. The ESA dosing system includes a model that represents a process by which red blood cells are produced in humans. The model may include one or more parameters, the values of which are patient-specific. The model takes into account patient-specific historical hemoglobin (Hgb) data and corresponding historical ESA dosage data to estimate the patient-specific values of the model parameters, and determines a target therapeutic dose of the ESA that may maintain the patient's Hgb within a target range.

Abstract: A positive displacement water meter includes a measuring chamber having an outlet port defined therein, wherein the outlet port includes a channel defined around the outlet port. A seal includes a planar surface and a curved surface, wherein the planar surface is substantially parallel to the curved surface, and the planar surface is situated within the channel. A meter casing includes an outlet port defined therein, wherein the meter casing receives the measuring chamber therein such that the outlet port of the measuring chamber is substantially aligned with the outlet port of the meter casing. The curved surface of the seal abuts a periphery of the outlet port of the meter casing forming a seal therewith. Due to the substantially arcuate cross section, the seal is adapted to resist the dislodging thereof from the channel during assembly of the positive displacement water meter.

Abstract: A gantry is constrained to move around the walls of a cylindrical, concrete tank. A rotating, high pressure water spray nozzle is mounted to a moveable platform on the gantry and connected to a source of water at a pressure of over 20,000 psi. The distance between the nozzle and an opposing surface of the wall of the tank is selected so the nozzle can remove the surface of the concrete and produce a selected surface roughness. The platform is moved vertically, with the gantry moving around the tank, so the surface of the concrete is systematically removed and roughened. A shotcrete or gunnite sprayer is then mounted to the platform, and the roughened surface sprayed with shotcrete or gunnite which sticks to the roughened surface. A tensioning head is then mounted to the platform, and wires or cables are tensioned as they are wrapped around the walls.

Abstract: A gantry is constrained to move around the walls of a cylindrical, concrete tank. A rotating, high pressure water spray nozzle is mounted to a moveable platform on the gantry and connected to a source of water at a pressure of over 20,000 psi. The distance between the nozzle and an opposing surface of the wall of the tank is selected so the nozzle can remove the surface of the concrete and produce a selected surface roughness. The platform is moved vertically, with the gantry moving around the tank, so the surface of the concrete is systematically removed and roughened. A shotcrete or gunnite sprayer is then mounted to the platform, and the roughened surface sprayed with shotcrete or gunnite which sticks to the roughened surface. A tensioning head is then mounted to the platform, and wires or cables are tensioned as they are wrapped around the walls.

Abstract: A device for positively restraining data tape cassettes within a magazine of a cassette loading assembly to prevent the cassettes from becoming dislodged from the magazine when the cassettes are not engaged within the tape drive. The device includes a spring loaded cantilever having an end section which engages a detent conventionally formed in the edge portion of the data cassette tape. When the cantilever end section is engaged in the detent, the cassette tape is securely held against a rear interior wall of the magazine. The spring loaded cantilever is pivotally mounted by a shaft to an interior side wall of the magazine. In operation, a cassette transfer system engages the tape cassette to load the cassette into the tape drive. However, prior to such engagement, a bracket mounted on the cassette transfer system contacts a load-receiving end of the cantilever opposite the end section within the cassette tape detent.

Abstract: A cordless four button cursor unit for accurately digitizing points along a digitizing tablet surface has an insulative housing including four buttons, each shaped as a quadrant of a circle and arranged about a hub. The hub acts as a stationary support from which an operator's fingers can conveniently "roll" to actuate any of the buttons. An antenna loop integral with a printed circuit board extends forward of the housing and subtends a cross hair on the bottom surface of a transparent substrate. A pair of conductive touch plates on opposite sides of the housing are short circuited by the resistance of an operator's hand, enabling an oscillator to effectuate operation of the cursor unit, causing the antenna to transmit electrostatic signals of frequencies representing button commands. The capacitance of the operator's body adds to the ground plane capacitance, so that transmission of electrostatic signals by the ground plane to the digitizing tablet is avoided.