Abstract: Methods and systems for generating optimized communications are provided. A digital communication network (DCN) is provided for a plurality of members of a population to communicate with each other. An initial communication is received from an individual member on the DCN. An optimized communication is generated based on optimizing the initial communication for one or more other members of the population while maintaining the same communication meaning as the initial communication. The optimized communication is then transmitted to the one or more other members.

Abstract: Various components for artificial candles and other lighting devices are described that can be used to create a realistic flame effect in the devices. The devices include a flame element that extends upwardly from a housing. A light source can be disposed with respect to the flame element such that the flame element is illuminated. A variety of drive mechanisms could be disposed within the body of the device that can cause movement of the flame element with respect to the housing. The flame element can be coupled to a housing or mounting bracket of the device using various components to suspend the flame element within the housing.

Abstract: Methods and systems for improving an effectiveness of reflection are provided. A digital communication network (DCN) is provided for a plurality of members of a population to interact with each other and the DCN. A communication from the DCN is transmitted to an individual member of the plurality of members and the communication comprises information about an availability of a biometric test to the individual member, and a request for the individual member to reflect on a lifestyle condition of the individual member and what the biometric test may reveal about the lifestyle condition. A response to the request is received from the individual member and the biometric test is provided to the individual member. A result of the biometric test is then reported to the individual member.

Abstract: Provided herein are peptide-based therapeutics that target POXP3 and methods of use thereof to decrease the immunosuppressive effects of Tregs and inhibit immune dysregulation, while sparring inhibition of activated cytotoxic T cells, for example, in the context of anti-tumor immune responses, autoimmunity, inflammatory conditions, etc.

Abstract: Methods and systems for managing an adverse health condition are provided. A digital communication network (DCN) is provided for a plurality of members of a population to interact with each other. A C-reactive protein (CRP) sample and at least one other inflammatory biomarker sample are received from an individual member. The CRP sample and the other inflammatory biomarker sample are analyzed and a CRP level and an inflammatory biomarker level are determined from the analysis. A composite result based on the CRP level and the inflammatory biomarker level is generated.

Abstract: Various components for artificial candles and other lighting devices are described that can be used to create a realistic flame effect in the devices. The devices include a flame element that extends upwardly from a housing. A light source can be disposed with respect to the flame element such that the flame element is illuminated. A variety of drive mechanisms could be disposed within the body of the device that can cause movement of the flame element with respect to the housing. The flame element can be coupled to a housing or mounting bracket of the device using various components to suspend the flame element within the housing.

Abstract: Systems and methods for automatically generating a record in a digital communication network (DCN) are provided. A DCN is provided for a plurality of members of a population to communicate with each other and/or with the DCN. At least one communication is analyzed and a record is generated for an individual member based on the analysis of the at least one communication. The record includes one or more lifestyle activities engaged in by the individual member, biometric data reported to the DCN regarding the individual member, and/or information regarding one or more relationships of the individual member. The record is also provided to the individual member through the DCN.

Abstract: To measure a member response in an individual member, a first resulting test point is measured before an activity. Then, at least a second resulting test point is measured at or after the activity. The member response can then be calculated as a function of the first resulting test point and the second resulting test point at the different times.

Abstract: Systems and methods for supporting health-based communications are provided. A digital communication network (DCN) for a plurality of members of a population to interact with each other and the DCN is provided. An invitation is transmitted to an individual member of the plurality of members to test a biological marker related to the adverse health condition and instructions are provided to the individual member to test the biological marker. A test result of the biological marker is received through the DCN and the individual member is enabled to share the test result with other members of the plurality of members through the DCN.

Abstract: Provided herein are peptide-based therapeutics that target FOXP3 and methods of use thereof to decrease the immuno-suppressive effects of Tregs and inhibit immune dysregulation, while sparring inhibition of activated cytotoxic T cells, for example, in the context of anti-tumor immune responses, autoimmunity, inflammatory conditions, etc.

Abstract: Various components for artificial candles and other lighting devices are described that can be used to create a realistic flame effect in the devices. The devices include a flame element that extends upwardly from a housing. A light source can be disposed with respect to the flame element such that the flame element is illuminated. A variety of drive mechanisms could be disposed within the body of the device that can cause movement of the flame element with respect to the housing. The flame element can be coupled to a housing or mounting bracket of the device using various components to suspend the flame element within the housing.

Abstract: Various components for artificial candles and other lighting devices are described that can be used to create a realistic flame effect in the devices. The devices include a flame element that extends upwardly from a housing. A light source can be disposed with respect to the flame element such that the flame element is illuminated. A variety of drive mechanisms could be disposed within the body of the device that can cause movement of the flame element with respect to the housing. The flame element can be coupled to a housing or mounting bracket of the device using various components to suspend the flame element within the housing.

Abstract: Various embodiments of electric lighting devices and, in particular, electric candles are described. The devices can include a flame element onto which light can be projected from a light source. Preferably, the light is projected within a focal area on the flame element. The housing of the devices can include projections that help maintain a vertical position of a circuit board within the housing.

Abstract: Various embodiments of electric lighting devices and, in particular, electric candles are described. The devices can include a flame element onto which light can be projected from a light source. Preferably, the light is projected within a focal area on the flame element. The housing of the devices can include projections that help maintain a vertical position of a circuit board within the housing.

Abstract: Various components for artificial candles and other lighting devices are described that can be used to create a realistic flame effect in the devices. The devices include a flame element that extends upwardly from a housing. A light source can be disposed with respect to the flame element such that the flame element is illuminated. A variety of drive mechanisms could be disposed within the body of the device that can cause movement of the flame element with respect to the housing. The flame element can be coupled to a housing or mounting bracket of the device using various components to suspend the flame element within the housing.

Abstract: Various embodiments of electric lighting devices and, in particular, electric candles are described. The devices can include a flame element onto which light can be projected from a light source. Preferably, the light is projected within a focal area on the flame element. The housing of the devices can include projections that help maintain a vertical position of a circuit board within the housing.

Abstract: Various components for artificial candles and other lighting devices are described that can be used to create a realistic flame effect in the devices. The devices include a flame element that extends upwardly from a housing. A light source can be disposed with respect to the flame element such that the flame element is illuminated. A variety of drive mechanisms could be disposed within the body of the device that can cause movement of the flame element with respect to the housing. The flame element can be coupled to a housing or mounting bracket of the device using various components to suspend the flame element within the housing.

Abstract: Various embodiments of electric lighting devices and, in particular, electric candles are described. The devices can include a flame element onto which light can be projected from a light source. Preferably, the light is projected within a focal area on the flame element. The housing of the devices can include projections that help maintain a vertical position of a circuit board within the housing.

Abstract: Various components for artificial candles and other lighting devices are described that can be used to create a realistic flame effect in the devices. The devices include a flame element that extends upwardly from a housing. A light source can be disposed with respect to the flame element such that the flame element is illuminated. A variety of drive mechanisms could be disposed within the body of the device that can cause movement of the flame element with respect to the housing. The flame element can be coupled to a housing or mounting bracket of the device using various components to suspend the flame element within the housing.

Abstract: Various embodiments of electric lighting devices and, in particular, electric candles are described. The devices can include a flame element onto which light can be projected from a light source. Preferably, the light is projected within a focal area on the flame element. The housing of the devices can include projections that help maintain a vertical position of a circuit board within the housing.