Patents by Inventor James Landers
James Landers has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230072999Abstract: A collection device for a biological sample to capture target compounds such as viruses or other pathogens or particles for testing from within the sample and move the captured target compound to a separate chamber for subsequent processing. The collection device can include an openable substance blister including capture particles located in a cup interior. Capture particles can attract and bind the target compounds from the sample. An extraction tube extracts any nucleic acid from the target compound for storage or subsequent amplification and testing to confirm presence of known microorganisms. The extraction tube can comprise a heat-deformable material and can be connected to a microfluidic cartridge for further processing of nucleic acid including, amplification and detection. The microfluidic cartridge includes valves and a plurality of chambers for amplification.Type: ApplicationFiled: August 5, 2022Publication date: March 9, 2023Inventors: Orion Scott, Christopher Birch, Daniel Mills, Brian Root, James Landers, Jingyi Li, Matthew Yeung, David Saul, David Vigil, Andrew Guy, Stan Wada, Betina De Gorordo, Steward Dodman, Tom Moran, Stuart Knowles, Fernando Dias, Rick Gardner
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Patent number: 11465145Abstract: A collection device for a biological sample to capture target compounds such as viruses or other pathogens or particles for testing from within the sample and move the captured target compound to a separate chamber for subsequent processing. The collection device can include an openable substance blister including capture particles located in a cup interior. Capture particles can attract and bind the target compounds from the sample. An extraction tube extracts any nucleic acid from the target compound for storage or subsequent amplification and testing to confirm presence of known microorganisms. The extraction tube can comprise a heat-deformable material and can be connected to a microfluidic cartridge for further processing of nucleic acid including, amplification and detection. The microfluidic cartridge includes valves and a plurality of chambers for amplification.Type: GrantFiled: August 26, 2021Date of Patent: October 11, 2022Inventors: Orion Scott, Christopher Birch, Daniel Mills, Brian Root, James Landers, Jingyi Li, Matthew Yeung, David Saul, David Vigil, Andrew Guy, Stan Wada, Betina De Gorordo, Steward Dodman, Tom Moran, Stuart Knowles, Fernando Dias, Rick Gardner
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Publication number: 20220114906Abstract: The present invention relates to a training system for training of a forward controller. The training system utilises a pod housing that can be attached to a hardpoint under an aircraft wing. The pod is configured to receive communications from the forward controller on the ground (or in another aircraft) and communicate wirelessly with an HMD and/or electronic device in the cockpit of the aircraft. This allows cheaper, less expensive aircraft to be used for training purposes.Type: ApplicationFiled: February 17, 2020Publication date: April 14, 2022Inventor: Anthony James LANDERS
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Publication number: 20220088601Abstract: A collection device for a biological sample to capture target compounds such as viruses or other pathogens or particles for testing from within the sample and move the captured target compound to a separate chamber for subsequent processing. The collection device can include an openable substance blister including capture particles located in a cup interior. Capture particles can attract and bind the target compounds from the sample. An extraction tube extracts any nucleic acid from the target compound for storage or subsequent amplification and testing to confirm presence of known microorganisms. The extraction tube can comprise a heat-deformable material and can be connected to a microfluidic cartridge for further processing of nucleic acid including, amplification and detection. The microfluidic cartridge includes valves and a plurality of chambers for amplification.Type: ApplicationFiled: August 26, 2021Publication date: March 24, 2022Inventors: ORION SCOTT, CHRISTOPHER BIRCH, DANIEL MILLS, BRIAN ROOT, JAMES LANDERS, JINGYI LI, MATTHEW YEUNG, DAVID SAUL, DAVID VIGIL, ANDREW GUY ., STAN WADA, BETINA DE GORORDO, STEWARD DODMAN, TOM MORAN, STUART KNOWLES, FERNANDO DIAS, RICK GARDNER
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Patent number: 10563253Abstract: A cartridge interface module (CIM), configured to engage with a removable microfluidic cartridge in a nucleic acid analyzer system can include a fluidics component, which is configured to initiate and support a liquid extraction of nucleic acids from a biological sample contained in the removable microfluidic cartridge. The CIM also includes a polymerase chain reaction (PCR) assembly component which can be configured to initiate and support amplification of the extracted nucleic acids. The CIM may also include a high voltage electrodes component that is configured to initiate and support separation of the amplified nucleic acids into nucleic acid fragments in a separation channel of the removable microfluidic cartridge. The CIM also includes a detection optics component that can be configured to collect, detect, and direct label nucleic acid fragments. The CIM is configured to integrate with a microfluidic chip architecture of an inserted removable microfluidic cartridge.Type: GrantFiled: February 7, 2019Date of Patent: February 18, 2020Inventors: Michael Edward Egan, Orion N. Scott, James Landers, Douglas J. South, Brian E. Root
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Publication number: 20200023366Abstract: Microfluidic devices for analyzing cellular components from biological samples which contain more than one cell type are provided. The microdevice separates cells by type, releases cellular components such as DNA (e.g. by cell lysis) and processes the cellular components (for example, by amplification) to generate products of interest for further analysis. Samples that can be analyzed using the microfluidic devices include forensic samples such as samples from sexual assault victims, and DNA profiling.Type: ApplicationFiled: February 7, 2018Publication date: January 23, 2020Inventors: Tracey Dawson CRUZ, James LANDERS
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Publication number: 20200002745Abstract: A cartridge interface module (CIM), configured to engage with a removable microfluidic cartridge in a nucleic acid analyzer system can include a fluidics component, which is configured to initiate and support a liquid extraction of nucleic acids from a biological sample contained in the removable microfluidic cartridge. The CIM also includes a polymerase chain reaction (PCR) assembly component which can be configured to initiate and support amplification of the extracted nucleic acids. The CIM may also include a high voltage electrodes component that is configured to initiate and support separation of the amplified nucleic acids into nucleic acid fragments in a separation channel of the removable microfluidic cartridge. The CIM also includes a detection optics component that can be configured to collect, detect, and direct label nucleic acid fragments. The CIM is configured to integrate with a microfluidic chip architecture of an inserted removable microfluidic cartridge.Type: ApplicationFiled: February 7, 2019Publication date: January 2, 2020Applicants: LOCKHEED MARTIN CORPORATION, ZYGEM CORPORATION LTD.Inventors: Michael Edward EGAN, Orion N. SCOTT, James LANDERS, Douglas J. SOUTH, Brian E. ROOT
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Patent number: 9988676Abstract: A microfluidic cartridge can include at least one nucleic acid analysis portion. Each nucleic acid analysis portion can include a fluidic network being configured for micro-liter volumes or less, a sample input at the beginning of the fluidic network, a plurality of vent ports and fluidic channels in the fluidic network configured to effectuate hydrodynamic movement within the fluidic network, an extraction mixture reservoir in the fluidic network, a mixing chamber in the fluidic network, an amplification chamber in the fluidic network, and a separation channel in the fluidic network. A nucleic acid analyzer can be capable of performing nucleic acid analysis using the microfluidic cartridge. A nucleic acid analysis method can be performed using the microfluidic cartridge.Type: GrantFiled: June 19, 2015Date of Patent: June 5, 2018Assignee: LEIDOS INNOVATIONS TECHNOLOGY, INC.Inventors: Michael E. Egan, Brian Root, Orion N. Scott, Douglas J. South, Joan M. Bienvenue, Paul Kinnon, James Landers, David Saul, An-Chi Tsuei, Jason Hayes, Matthew Springer, Matthew Solomon, Peter Van Ruijven
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Patent number: 9732557Abstract: A wheel and bracket device that is removably attachable to a ladder. The present invention allows users to more conveniently transport a ladder, ladder tree stand, or other such device, along with objects that may be supported thereon. The present invention is a bracket that is adapted to enclose a rail and a rung of a ladder and be securely affixed to the ladder via a locking mechanism, such as a locking pin. A wheel is rotatably attached to the bracket, thereby allowing users to push or pull the ladder across terrain, rather than being forced to carry the ladder.Type: GrantFiled: October 15, 2014Date of Patent: August 15, 2017Inventor: James Landers
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Patent number: 9692446Abstract: An integrated circuit (IC) chip containing a Delta-Sigma (??) filter module for a ?? analog-to-digital converter and a method of providing analog to digital conversion are disclosed. The IC chip includes a ?? filter that is connected to receive a digital data stream created by a ?? modulator, provide a multibit data value when a counter reaches a selected number of received bits, and reset the counter responsive to receiving a synchronization pulse. The IC chip also includes a FIFO buffer connected to store the multibit data value only when a synchronization flag is on and to send an interrupt towards a processing unit only after storing a selected number of multibit data values. The IC chip further includes a synchronization module connected to turn on the synchronization flag responsive to receiving the synchronization pulse and to turn off the synchronization flag responsive to the sending of the interrupt.Type: GrantFiled: September 30, 2016Date of Patent: June 27, 2017Assignee: TEXAS INSTRUMENTS INCORPORATEDInventor: Robert James Landers
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Publication number: 20170134039Abstract: An integrated circuit (IC) chip containing a Delta-Sigma (??) filter module for a ?? analog-to-digital converter and a method of providing analog to digital conversion are disclosed. The IC chip includes a ?? filter that is connected to receive a digital data stream created by a ?? modulator, provide a multibit data value when a counter reaches a selected number of received bits, and reset the counter responsive to receiving a synchronization pulse. The IC chip also includes a FIFO buffer connected to store the multibit data value only when a synchronization flag is on and to send an interrupt towards a processing unit only after storing a selected number of multibit data values. The IC chip further includes a synchronization module connected to turn on the synchronization flag responsive to receiving the synchronization pulse and to turn off the synchronization flag responsive to the sending of the interrupt.Type: ApplicationFiled: September 30, 2016Publication date: May 11, 2017Inventor: Robert James Landers
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Patent number: 9630182Abstract: A microfluidic chip includes one or more reaction chambers to hold fluids for chemical or biochemical reactions, such as PCR. A non-contact heat source heats the reaction chamber and the fluid, such that the heat source does not contact the reaction chamber or the fluid. The heat source can heat the reaction chamber and the fluid separately, where the reaction chamber and the fluid separately absorb heat radiation from the heat source. A temperature sensor acquires a temperature of the reaction chamber and/or the fluid. Control circuitry controls the heat source according to a cycling profile for the reaction in the fluid to cycle the heat source between heating and not heating the reaction chamber and the fluid based on the temperature acquired by the temperature sensor. Cooling can be provided passively or actively.Type: GrantFiled: December 4, 2013Date of Patent: April 25, 2017Inventors: Michael Edward Egan, Peter Karl Trost, James Landers, Brian Root, Orion Scott
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Patent number: 9322054Abstract: A microfluidic cartridge can include at least one nucleic acid analysis portion. Each nucleic acid analysis portion can include a fluidic network being configured for micro-liter volumes or less, a sample input at the beginning of the fluidic network, a plurality of vent ports and fluidic channels in the fluidic network configured to effectuate hydrodynamic movement within the fluidic network, an extraction mixture reservoir in the fluidic network, a mixing chamber in the fluidic network, an amplification chamber in the fluidic network, and a separation channel in the fluidic network. A nucleic acid analyzer can be capable of performing nucleic acid analysis using the microfluidic cartridge. A nucleic acid analysis method can be performed using the microfluidic cartridge.Type: GrantFiled: February 21, 2013Date of Patent: April 26, 2016Assignees: Lockheed Martin Corporation, MICROLAB DIAGNOSTICS, INC.Inventors: Michael Egan, Brian Root, Orion N. Scott, Douglas J. South, Joan Bienvenue, Paul Kinnon, James Landers, David Saul, An-Chi Tsuei, Jason Hayes, Matthew Springer, Matthew Solomon, Peter van Ruijven
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Publication number: 20150284775Abstract: A microfluidic cartridge can include at least one nucleic acid analysis portion. Each nucleic acid analysis portion can include a fluidic network being configured for micro-liter volumes or less, a sample input at the beginning of the fluidic network, a plurality of vent ports and fluidic channels in the fluidic network configured to effectuate hydrodynamic movement within the fluidic network, an extraction mixture reservoir in the fluidic network, a mixing chamber in the fluidic network, an amplification chamber in the fluidic network, and a separation channel in the fluidic network. A nucleic acid analyzer can be capable of performing nucleic acid analysis using the microfluidic cartridge. A nucleic acid analysis method can be performed using the microfluidic cartridge.Type: ApplicationFiled: June 19, 2015Publication date: October 8, 2015Applicants: LOCKHEED MARTIN CORPORATION, MICROLAB DIAGNOSTICS, INC.Inventors: Michael E. EGAN, Brian Root, Orion N. Scott, Douglas J. South, Joan M. Bienvenue, Paul Kinnon, James Landers, David Saul, An-Chi Tsuei, Jason Hayes, Matthew Springer, Matthew Solomon, Peter Van Ruijven
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Publication number: 20150270272Abstract: A method and circuit in which the drive strength of a FinFET transistor can be selectively modified, and in particular can be selectively reduced, by omitting the LDD extension formation in the source and/or in the drain of the FinFET. One application of this approach is to enable differentiation of the drive strengths of transistors in an integrated circuit by applying the technique to some, but not all, of the transistors in the integrated circuit. In particular in a SRAM cell formed from FinFET transistors the application of the technique to the pass-gate transistors, which leads to a reduction of the drive strength of the pass-gate transistors relative to the drive strength of the pull-up and pull-down transistors, results in improved SRAM cell performance.Type: ApplicationFiled: June 1, 2015Publication date: September 24, 2015Inventors: Thomas Merelle, Gerben Doornbos, Robert James Lander, Yi-Tzi Liu
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Publication number: 20150204139Abstract: A wheel and bracket device that is removably attachable to a ladder. The present invention allows users to more conveniently transport a ladder, ladder tree stand, or other such device, along with objects that may be supported thereon. The present invention is a bracket that is adapted to enclose a rail and a rung of a ladder and be securely affixed to the ladder via a locking mechanism, such as a locking pin. A wheel is rotatably attached to the bracket, thereby allowing users to push or pull the ladder across terrain, rather than being forced to carry the ladder.Type: ApplicationFiled: October 15, 2014Publication date: July 23, 2015Inventor: James Landers
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Publication number: 20150151302Abstract: A microfluidic chip includes one or more reaction chambers to hold fluids for chemical or biochemical reactions, such as PCR. A non-contact heat source heats the reaction chamber and the fluid, such that the heat source does not contact the reaction chamber or the fluid. The heat source can heat the reaction chamber and the fluid separately, where the reaction chamber and the fluid separately absorb heat radiation from the heat source. A temperature sensor acquires a temperature of the reaction chamber and/or the fluid. Control circuitry controls the heat source according to a cycling profile for the reaction in the fluid to cycle the heat source between heating and not heating the reaction chamber and the fluid based on the temperature acquired by the temperature sensor. Cooling can be provided passively or actively.Type: ApplicationFiled: December 4, 2013Publication date: June 4, 2015Applicants: ZyGEM CORPORATION LTD., LOCKHEED MARTIN CORPORATIONInventors: Michael Edward EGAN, Peter Karl Trost, James Landers, Brian Root, Orion Scott
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Patent number: 9048122Abstract: A device and method of fabricating the same are disclosed. In an example, a device includes a first fin Field Effect Transistors (finFET) formed on a substrate. The first finFET including a fin formed on the substrate. The device further includes a second finFET formed on the substrate. The first finFET and the second finFET share the fin and wherein the first finFET is without any low density doped (LDD) extension region in the substrate and wherein the second FinFET is associated with a first LDD extension region formed in the substrate such that a drive strength of the second finFET is greater relative to a drive strength of the first finFET.Type: GrantFiled: July 11, 2014Date of Patent: June 2, 2015Assignee: Taiwan Semiconductor Manufacturing Company, Ltd.Inventors: Thomas Merelle, Gerben Doornbos, Robert James Lander
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Publication number: 20140319609Abstract: A method and circuit in which the drive strength of a FinFET transistor can be selectively modified, and in particular can be selectively reduced, by omitting the LDD extension formation in the source and/or in the drain of the FinFET. One application of this approach is to enable differentiation of the drive strengths of transistors in an integrated circuit by applying the technique to some, but not all, of the transistors in the integrated circuit. In particular in a SRAM cell formed from FinFET transistors the application of the technique to the pass-gate transistors, which leads to a reduction of the drive strength of the pass-gate transistors relative to the drive strength of the pull-up and pull-down transistors, results in improved SRAM cell performance.Type: ApplicationFiled: July 11, 2014Publication date: October 30, 2014Inventors: Thomas Merelle, Gerben Doornbos, Robert James Lander
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Publication number: 20140295441Abstract: A cartridge interface module (CIM), configured to engage with a removable microfluidic cartridge in a nucleic acid analyzer system can include a fluidics component, which is configured to initiate and support a liquid extraction of nucleic acids from a biological sample contained in the removable microfluidic cartridge. The CIM also includes a polymerase chain reaction (PCR) assembly component which can be configured to initiate and support amplification of the extracted nucleic acids. The CIM may also include a high voltage electrodes component that is configured to initiate and support separation of the amplified nucleic acids into nucleic acid fragments in a separation channel of the removable microfluidic cartridge. The CIM also includes a detection optics component that can be configured to collect, detect, and direct label nucleic acid fragments. The CIM is configured to integrate with a microfluidic chip architecture of an inserted removable microfluidic cartridge.Type: ApplicationFiled: March 27, 2014Publication date: October 2, 2014Applicants: ZYGEM CORPORATION LTD., LOCKHEED MARTIN CORPORATIONInventors: Michael Edward EGAN, Orion N. Scott, James Landers, Douglas J. South, Brian E. Root