Patents by Inventor James Langham

James Langham has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10415047
    Abstract: This invention discloses a constitutive promoter from the Taro bacilliform virus (TaBV) for expression of foreign or endogenous coding sequences in plants, including dicotyledonous and monocotyledonous plants. The invention also discloses a chimeric nucleic acid construct comprising the promoter of the invention operably linked to a foreign or endogenous polynucleotide that codes for a protein of interest or a transcript capable of modulating expression of a target gene. The invention further discloses transformed plant cells, as well as differentiated plants and plant parts, containing the construct. Methods for diagnosis and treatment of viral infections, especially badnaviral infections, are also disclosed.
    Type: Grant
    Filed: June 28, 2016
    Date of Patent: September 17, 2019
    Assignee: Farmacule Bioindustries Pty Ltd
    Inventors: James Langham Dale, Robert Maxwell Harding, Douglas Kenneth Becker, Gregory John Hafner, Ilin Yang
  • Publication number: 20180105821
    Abstract: This invention discloses a constitutive promoter from the Taro bacilliform virus (TaBV) for expression of foreign or endogenous coding sequences in plants, including dicotyledonous and monocotyledonous plants. The invention also discloses a chimeric nucleic acid construct comprising the promoter of the invention operably linked to a foreign or endogenous polynucleotide that codes for a protein of interest or a transcript capable of modulating expression of a target gene. The invention further discloses transformed plant cells, as well as differentiated plants and plant parts, containing the construct. Methods for diagnosis and treatment of viral infections, especially badnaviral infections, are also disclosed.
    Type: Application
    Filed: June 28, 2016
    Publication date: April 19, 2018
    Applicant: Farmacule Bioindustries Pty Ltd
    Inventors: James Langham DALE, Robert Maxwell Harding, Douglas Kenneth Becker, Gregory John Hafner, llin Yang
  • Patent number: 9416365
    Abstract: This invention discloses a constitutive promoter for expression of foreign or endogenous coding sequences in plants, including dicotyledonous and monocotyledonous plants. The invention also discloses a chimeric nucleic acid construct comprising the promoter of the invention operably linked to a foreign or endogenous polynucleotide that codes for a protein of interest or a transcript capable of modulating expression of a target gene. The invention further discloses transformed plant cells, as well as differentiated plants and plant parts, containing the construct. Methods for diagnosis and treatment of viral infections, especially badnaviral infections, are also disclosed.
    Type: Grant
    Filed: September 30, 2009
    Date of Patent: August 16, 2016
    Assignee: Farmacule Bioindustries Pty Ltd
    Inventors: James Langham Dale, Robert Maxwell Harding, Douglas Kenneth Becker, Gregory John Hafner, Ilin Yang
  • Patent number: 8829170
    Abstract: The present invention relates generally to constructs and in particular genetic constructs comprising polynucleotide sequences capable of release in covalently closed, circular form from a larger nucleotide sequence such as, but not limited to, a genome of a eukaryotic cell. Preferably, once released, a polynucleotide sequence is reconstituted in a form which permits expression of the polynucleotide sequence. In one embodiment, the reconstituted polynucleotide sequence comprises a coding sequence with all or part of an extraneous nucleotide such as, but not limited to, an intronic sequence or other splice signal inserted therein. Expression and in particular transcription of the coding sequence involves splicing out the extraneous sequence. The release and circularization is generally in response to a stimulus such as a protein-mediated stimulus. More particularly, the protein is a viral or prokaryotic or eukaryotic derived protein or developmentally and/or tissue specific regulated protein.
    Type: Grant
    Filed: November 17, 2010
    Date of Patent: September 9, 2014
    Assignee: Queensland University of Technology
    Inventors: James Langham Dale, Benjamin Dugdale, Greg John Hafner, Scott Richard Hermann, Douglas Kenneth Becker, Robert Maxwell Harding, Srimek Chowpongpang
  • Publication number: 20110119782
    Abstract: The present invention relates generally to constructs and in particular genetic constructs comprising polynucleotide sequences capable of release in covalently closed, circular form from a larger nucleotide sequence such as, but not limited to, a genome of a eukaryotic cell. Preferably, once released, a polynucleotide sequence is reconstituted in a form which permits expression of the polynucleotide sequence. In one embodiment, the reconstituted polynucleotide sequence comprises a coding sequence with all or part of an extraneous nucleotide such as, but not limited to, an intronic sequence or other splice signal inserted therein. Expression and in particular transcription of the coding sequence involves splicing out the extraneous sequence. The release and circularization is generally in response to a stimulus such as a protein-mediated stimulus. More particularly, the protein is a viral or prokaryotic or eukaryotic derived protein or developmentally and/or tissue specific regulated protein.
    Type: Application
    Filed: November 17, 2010
    Publication date: May 19, 2011
    Applicant: Queensland University of Technology
    Inventors: James Langham Dale, Benjamin Dugdale, Greg John Hafner, Scott Richard Hermann, Douglas Kenneth Becker, Robert Maxwell Harding, Srimek Chowpongpang
  • Patent number: 7863430
    Abstract: The present invention relates generally to constructs and in particular genetic constructs comprising polynucleotide sequences capable of release in covalently closed, circular form from a larger nucleotide sequence such as a genome of a eukaryotic cell. Preferably, once released, a polynucleotide sequence is reconstituted in a form which permits expression of the polynucleotide sequence. In one embodiment, the reconstituted polynucleotide sequence comprises a coding sequence with all or part of an extraneous nucleotide such as an intronic sequence or other splice signal inserted therein. Expression and in particular transcription of the coding sequence involves splicing out the extraneous sequence. The release and circularization is generally in response to a stimulus such as a protein-mediated stimulus. More particularly, the protein is a viral or prokaryotic or eukaryotic derived protein or developmentally and/or tissue specific regulated protein.
    Type: Grant
    Filed: March 28, 2001
    Date of Patent: January 4, 2011
    Assignee: Queensland University of Technology
    Inventors: James Langham Dale, Benjamin Dugdale, Greg John Hafner, Scott Richard Hermann, Douglas Kenneth Becker, Robert Maxwell Harding, Srimek Chowpongpang
  • Publication number: 20100281566
    Abstract: This invention discloses a constitutive promoter for expression of foreign or endogenous coding sequences in plants, including dicotyledonous and monocotyledonous plants. The invention also discloses a chimeric nucleic acid construct comprising the promoter of the invention operably linked to a foreign or endogenous polynucleotide that codes for a protein of interest or a transcript capable of modulating expression of a target gene. The invention further discloses transformed plant cells, as well as differentiated plants and plant parts, containing the construct. Methods for diagnosis and treatment of viral infections, especially badnaviral infections, are also disclosed.
    Type: Application
    Filed: September 30, 2009
    Publication date: November 4, 2010
    Applicant: Queensland University of Technology
    Inventors: James Langham Dale, Robert Maxwell Harding, Douglas Kenneth Becker, Gregory John Hafner, Ilin Yang
  • Patent number: 7601887
    Abstract: The present invention relates to two banana resistant genes, RGA5 and RGA2, and methods of producing transgenic plants having resistance to fusarium by transforming the plants with RGA5 or RGA2 polynucleotide sequences. The invention also relates to plants transformed with the RGA5 or RGA2 polynucleotide sequences, and methods of breeding plants for fusarium resistance by crossing transformed plants expressing RGA5 or RGA2 polypeptides with fusarium susceptible plants.
    Type: Grant
    Filed: September 23, 2004
    Date of Patent: October 13, 2009
    Assignee: Queensland University of Technology
    Inventors: James Langham Dale, Santy Peraza Echeverria
  • Patent number: 7598366
    Abstract: This invention discloses a constitutive promoter from the Taro bacilliform virus (TaBV) for expression of foreign or endogenous coding sequences in plants, including dicotyledonous and monocotyledonous plants. The invention also discloses a chimeric nucleic acid construct comprising the promoter of the invention operably linked to a foreign or endogenous polynucleotide that codes for a protein of interest or a transcript capable of modulating expression of a target gene. The invention further discloses transformed plant cells, as well as differentiated plants and plant parts, containing the construct. Methods for diagnosis and treatment of viral infections, especially badnaviral infections, are also disclosed.
    Type: Grant
    Filed: July 17, 2003
    Date of Patent: October 6, 2009
    Assignee: Queensland University of Technology
    Inventors: James Langham Dale, Robert Maxwell Harding, Douglas Kenneth Becker, Gregory John Hafner, Ilin Yang
  • Patent number: 7358047
    Abstract: The present invention relates generally to a method of amplifying closed circular nucleic acid probes and, more particularly, to a method of amplifying closed circular nucleic acid probes by rolling circle amplification. The method of the present invention is useful in a range of applications involving the detection of nucleic acid sequences such as, but not limited to, the identification of genetic disorders, genetic variants or the presence of microbiological or viral agents.
    Type: Grant
    Filed: August 13, 2004
    Date of Patent: April 15, 2008
    Assignee: QIAGEN GmbH
    Inventors: Gregory John Hafner, Philip Morrison Giffard, Lindsay Colin Wolter, James Langham Dale, Mark Richard Stafford, Ilin Chen Hai-Ni Yang, Joanne Voisey
  • Patent number: 6830884
    Abstract: The present invention relates generally to a method of amplifying closed circular nucleic acid probes and, more particularly, to a method of amplifying closed circular nucleic acid probes by rolling circle amplification. The method of the present invention is useful in a range of applications involving the detection of nucleic acid sequences such as, but not limited to, the identification of genetic disorders, genetic variants or the presence of microbiological or viral agents.
    Type: Grant
    Filed: December 14, 1999
    Date of Patent: December 14, 2004
    Assignee: Molecular Staging Inc.
    Inventors: Gregory John Hafner, Philip Morrison Giffard, Lindsay Colin Wolter, James Langham Dale, Mark Richard Stafford, Ilin Chen Hai-Ni Yang, Joanne Voisey
  • Publication number: 20040121430
    Abstract: The present invention relates generally to constructs and in particular genetic constructs comprising polynucleotide sequences capable of release in covalently closed, circular form from a larger nucleotide sequence such as[, but not limited to,] a genome of a eukaryotic cell. Preferably, once released, a polynucleotide sequence is reconstituted in a form which permits expression of the polynucleotide sequence. In one embodiment, the reconstituted polynucleotide sequence comprises a coding sequence with all or part of an extraneous nucleotide such as[, but not limited to,] an intronic sequence or other splice signal inserted therein. Expression and in particular transcription of the coding sequence involves splicing out the extraneous sequence. The release and circularization is generally in response to a stimulus such as a protein-mediated stimulus.
    Type: Application
    Filed: January 22, 2003
    Publication date: June 24, 2004
    Inventors: James Langham Dale, Benjamin Dugdale, Greg John Hafner, Scott Richard Hermann, Douglas Kenneth Becker, Robert Maxwell Harding, Srimek Chowpongpang
  • Publication number: 20030218370
    Abstract: A chair has a seat mounted on a pedestal with a swivel and tilt function. The pedestal has an inner part and an outer part that are telescopically engaged. The outer part rotates with respect to the inner part. A bracket secures the underside of the seat to the upper end of the outer part. There are a series of holes in the upper end of the outer part. A selectively operable locking member mounts on the bracket. The locking member includes a detent for engaging in one of the holes. A releasing member releases the detent from one of the holes and enables insertion in another hole after rotation of the outer part relative to the inner part. A spring can bias the detent to the engaged position. The seat can neither be swivelled nor tilted when the locking member is in engaged position.
    Type: Application
    Filed: June 4, 2003
    Publication date: November 27, 2003
    Applicant: The Bambach Saddle Seat (Europe) Limited
    Inventor: Christopher James Langham
  • Publication number: 20010015400
    Abstract: The invention relates to apparatus for adjusting the angular position of one member relative to another, comprising means releasably lockably engageable with the one member therefor whereby the means is operable to lock and unlock the one member with respect to the another member. There is a remote actuating means for the means.
    Type: Application
    Filed: February 21, 2001
    Publication date: August 23, 2001
    Inventor: Christopher James Langham
  • Patent number: 6127604
    Abstract: The invention relates a DNA molecule which is a partial fragment of an intergenic region of a BBTV component or alternatively which DNA molecule is derived from said intergenic region whereby the DNA molecule is capable of promoting, enhancing, regulating, or modifying transcription of a non-BBTV gene.
    Type: Grant
    Filed: March 12, 1998
    Date of Patent: October 3, 2000
    Assignee: Queensland University of Technology
    Inventors: James Langham Dale, Robert Maxwell Harding, Benjamin Dugdale, Peter Ronald Beetham, Gregory John Hafner, Douglas Kenneth Becker
  • Patent number: 5856092
    Abstract: A method for detecting a specific polynucleotide sequence in a material is disclosed. The method includes exposing said material to an oligonucleotide primer having a sequence complementary to part of said specific polynucleotide sequence wherein said primer binds to part of said polynucleotide sequence when present in said material. Primer bound to the polynucleotide sequence is extended wherein any extended primer includes a detectable element and/or a separation element. Any extended primer is then separated into a fraction wherein said fraction does not have detectable element not included in said extended primer.
    Type: Grant
    Filed: April 27, 1995
    Date of Patent: January 5, 1999
    Assignee: Geneco Pty Ltd
    Inventors: James Langham Dale, Peter Timms, Terence Patrick Walsh
  • Patent number: 5756708
    Abstract: The invention provides DNA molecules consisting essentially of a nucleotide sequence or part thereof which are asosciated with the genome of banana bunchy top virus (BBTV) as illustrated in FIGS. 1 through 8 (SEQ ID NOS: 49-54, 27-37, 55-60, 38-48, and 9-23, respectively) of the specification attached herewith.
    Type: Grant
    Filed: February 24, 1994
    Date of Patent: May 26, 1998
    Assignee: Queensland University of Technology
    Inventors: Mirko Karan, Thomas Michael Burns, James Langham Dale, Robert Maxwell Harding
  • Patent number: 4716692
    Abstract: An arrangement for interconnecting wall panels of corresponding construction with one another to form walls of predetermined size and orientation is disclosed. The arrangement comprises a series of spaced apart parallel channels in the vertical sides of the wall panels; outwardly and upwardly extending fingers along each vertical side of each of the wall panels and positioned between the parallel channels; a columnar vertical standard which is received between the respective vertical sides of the adjoining wall panels and which column includes a plurality of spaced apart parallel vertical flanges which are of a size and spacing for being engagingly received in the channels; and parallel sets of vertical web members positioned at locations along the columnar standard which correspond to the location of the upwardly facing fingers along each vertical side of the adjoining wall panels.
    Type: Grant
    Filed: December 30, 1986
    Date of Patent: January 5, 1988
    Assignee: Alma Desk Company
    Inventors: Thomas Harper, James Langham, Francis J. Idol