Patents by Inventor James Lim

James Lim has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240301350
    Abstract: Embodiments of a method of modulating a potency level phenotype of a source population of cells include culturing the source cell population in a liquid medium within a cell culture incubator, the incubator is configured to independently regulate one or more variable parameters of gaseous conditions within the incubator, the more than one variable atmospheric parameters within the incubator being regulated independently of each other and independently of ambient external gaseous conditions. The method further includes regulating the one or more variable parameters of the gaseous condition within the incubator such that at least one of the one or more variable parameter differs from an ambient level of the respective variable parameter, and as a consequence of such difference from ambient conditions, the subset population is driven from a first potency level phenotype to a second potency level phenotype.
    Type: Application
    Filed: October 6, 2023
    Publication date: September 12, 2024
    Inventors: James LIM, Bruce ADAMS, Zack PAPPALARDO, Brian FETH
  • Publication number: 20240002774
    Abstract: Embodiments of a cell culture incubator system provided herein have two or more individual incubators and atmospheric regulation system configured to regulate atmospheric conditions within the environmental chamber of each individual incubator. The atmospheric regulation system has a single integrated controller system that controls atmospheric regulation of each of the individual incubators independently of the one or more other individual incubators. Atmospheric conditions within each of the individual incubators include at least the oxygen level and the total gas pressure, which are regulated independently of each other.
    Type: Application
    Filed: May 8, 2023
    Publication date: January 4, 2024
    Inventors: James LIM, Brian FETH, Becky RUTHERFORD, Janette Trang PHI, Nicholas George ERNDT
  • Patent number: 11814647
    Abstract: Embodiments of a method of modulating a potency level phenotype of a source population of cells include culturing the source cell population in a liquid medium within a cell culture incubator, the incubator is configured to independently regulate one or more variable parameters of gaseous conditions within the incubator, the more than one variable atmospheric parameters within the incubator being regulated independently of each other and independently of ambient external gaseous conditions. The method further includes regulating the one or more variable parameters of the gaseous condition within the incubator such that at least one of the one or more variable parameter differs from an ambient level of the respective variable parameter, and as a consequence of such difference from ambient conditions, the subset population is driven from a first potency level phenotype to a second potency level phenotype.
    Type: Grant
    Filed: March 26, 2021
    Date of Patent: November 14, 2023
    Assignee: XCELL BIOSCIENCES, INC.
    Inventors: James Lim, Bruce Adams, Zack Pappalardo, Brian Feth
  • Publication number: 20230212500
    Abstract: Embodiments of the provided technology relate to a gas flow and liquid flow regulation system within a cell culture instrument. Embodiments of the gas and liquid flow regulation system include a pressurizable gas-mixing chamber, a cell culture compartment that includes a cell culture vessel having and a gas space, and a gas flow system. The gas flow system is driven by gas pressure, and is adaptable to provide an atmospheric condition of hypoxia and hyperbaric pressure within the cell culture compartment. The liquid flow regulation system is driven by hydraulic pressure.
    Type: Application
    Filed: October 28, 2022
    Publication date: July 6, 2023
    Inventors: Nicholas George ERNDT, Genevieve PEDROTTI, James LIM, Brian FETH, Quynh Anh Thuc LU
  • Publication number: 20230122362
    Abstract: Example embodiments of the described technology provide an apparatus for testing an electrochemical system. The apparatus may comprise a testing module electrically coupled to the electrochemical system. The testing module may comprise a discharge circuit configured to draw current from the electrochemical system at a plurality of different rates. The discharge circuit may be configured to continuously draw current from the electrochemical system once a test of the electrochemical system is commenced. The apparatus may also comprise a measurement module which may be configured to measure voltage across terminals of the electrochemical system and current drawn from the electrochemical system during the test. The apparatus may also comprise a processor. The processor may be configured to compensate at least in part the measured voltage for voltage drift which was generated by continuously drawing current from the electrochemical system.
    Type: Application
    Filed: March 25, 2021
    Publication date: April 20, 2023
    Inventors: Tina SHOA HASSANI LASHIDANI, Gregory John FUNK, Mark Steven RICHTER, April Petrovna Zoom O'DWYER, Tarek Lawrence WARD, Yat Shun (Damien) YU, Kevin Norman HADDEN, Alex James LIM, Marvin MESSING
  • Publication number: 20220213439
    Abstract: The present disclosure relates to a method of modulating a phenotype a source population of cells to assume a desired phenotype. The method includes culturing the source cell population within an incubator configured to regulate the variable atmospheric parameters of oxygen level and total atmospheric pressure level.
    Type: Application
    Filed: April 30, 2020
    Publication date: July 7, 2022
    Inventors: James LIM, Quynh Anh Thuc LU, Yunmin LI, Brian FETH
  • Patent number: 11365390
    Abstract: Embodiments of a method of modulating a potency level phenotype of a source population of cells include culturing the source cell population in a liquid medium within a cell culture incubator, the incubator is configured to independently regulate one or more variable parameters of gaseous conditions within the incubator, the more than one variable atmospheric parameters within the incubator being regulated independently of each other and independently of ambient external gaseous conditions. The method further includes regulating the one or more variable parameters of the gaseous condition within the incubator such that at least one of the one or more variable parameter differs from an ambient level of the respective variable parameter, and as a consequence of such difference from ambient conditions, the subset population is driven from a first potency level phenotype to a second potency level phenotype.
    Type: Grant
    Filed: December 18, 2018
    Date of Patent: June 21, 2022
    Assignee: XCELL BIOSCIENCES, INC.
    Inventors: James Lim, Bruce Adams, Zack Pappalardo, Brian Feth
  • Patent number: 11340247
    Abstract: A method includes generating motion data by receiving a gyroscope data from a gyroscope sensor, performing integration using the gyroscope data and generating an integrated gyroscope data using a first processor. The method further includes receiving a data from one or more sensors, other than the gyroscope sensor, and performing sensor fusion using the integrated gyroscope data and the data to generate motion data using a second processor.
    Type: Grant
    Filed: October 15, 2020
    Date of Patent: May 24, 2022
    Assignee: Invensense, Inc.
    Inventors: William Kerry Keal, James Lim, Sinan Karahan
  • Publication number: 20210388306
    Abstract: Embodiments of the invention relate to a cell culture incubator having a gas flow regulation system that exerts control over atmospheric parameters within the incubator. Particular embodiments include an enclosed environmental chamber and a control unit operably linked thereto, the control unit having an oxygen module and a pressure module. Control unit embodiments, by way of these modules, are configured to regulate both oxygen partial pressure and total gas pressure within the enclosed environmental chamber. Embodiments of the control unit are adapted (a) to provide instructions to the oxygen module to regulate an oxygen level to an instructed hypoxic oxygen level and (b) to provide instructions to the pressure module to regulate total gas pressure to an instructed positive pressure level. The regulation of oxygen to the instructed hypoxic level prevails despite an oxygen partial pressure-increasing effect of the positive pressure condition associated with the instructed positive pressure level.
    Type: Application
    Filed: August 20, 2021
    Publication date: December 16, 2021
    Inventors: James LIM, Luke CASSEREAU
  • Publication number: 20210371801
    Abstract: Embodiments of the invention relate to a cell culture incubator having a gas flow regulation system that exerts control over atmospheric parameters within the incubator. Particular embodiments include an enclosed environmental chamber and a control unit operably linked thereto, the control unit having an oxygen module and a pressure module. Control unit embodiments, by way of these modules, are configured to regulate both oxygen partial pressure and total gas pressure within the enclosed environmental chamber. Embodiments of the control unit are adapted (a) to provide instructions to the oxygen module to regulate an oxygen level to an instructed hypoxic oxygen level and (b) to provide instructions to the pressure module to regulate total gas pressure to an instructed positive pressure level. The regulation of oxygen to the instructed hypoxic level prevails despite an oxygen partial pressure-increasing effect of the positive pressure condition associated with the instructed positive pressure level.
    Type: Application
    Filed: June 1, 2021
    Publication date: December 2, 2021
    Inventors: James LIM, Luke CASSEREAU
  • Publication number: 20210214679
    Abstract: Embodiments of a method of modulating a potency level phenotype of a source population of cells include culturing the source cell population in a liquid medium within a cell culture incubator, the incubator is configured to independently regulate one or more variable parameters of gaseous conditions within the incubator, the more than one variable atmospheric parameters within the incubator being regulated independently of each other and independently of ambient external gaseous conditions. The method further includes regulating the one or more variable parameters of the gaseous condition within the incubator such that at least one of the one or more variable parameter differs from an ambient level of the respective variable parameter, and as a consequence of such difference from ambient conditions, the subset population is driven from a first potency level phenotype to a second potency level phenotype.
    Type: Application
    Filed: March 26, 2021
    Publication date: July 15, 2021
    Inventors: James LIM, Bruce ADAMS, Zack PAPPALARDO, Brian FETH
  • Patent number: 10996086
    Abstract: Various aspects of this disclosure comprise systems and methods for synchronizing sensor data acquisition and/or output. For example, various aspects of this disclosure provide for achieving a desired level of timing accuracy in a MEMS sensor system, even in an implementation in which timer drift is substantial.
    Type: Grant
    Filed: December 23, 2019
    Date of Patent: May 4, 2021
    Assignee: InvenSense, Inc.
    Inventors: Andy Milota, James Lim, William Kerry Keal
  • Publication number: 20210032587
    Abstract: Embodiments of a cell culture incubator system provided herein have two or more individual incubators and atmospheric regulation system configured to regulate atmospheric conditions within the environmental chamber of each individual incubator. The atmospheric regulation system has a single integrated controller system that controls atmospheric regulation of each of the individual incubators independently of the one or more other individual incubators. Atmospheric conditions within each of the individual incubators include at least the oxygen level and the total gas pressure, which are regulated independently of each other.
    Type: Application
    Filed: February 4, 2019
    Publication date: February 4, 2021
    Inventors: James LIM, Brian FETH, Becky RUTHERFORD, Janette Trang PHI, Nicholas George ERNDT
  • Publication number: 20210025914
    Abstract: A method includes generating motion data by receiving a gyroscope data from a gyroscope sensor, performing integration using the gyroscope data and generating an integrated gyroscope data using a first processor. The method further includes receiving a data from one or more sensors, other than the gyroscope sensor, and performing sensor fusion using the integrated gyroscope data and the data to generate motion data using a second processor.
    Type: Application
    Filed: October 15, 2020
    Publication date: January 28, 2021
    Inventors: William Kerry Keal, James Lim, Sinan Karahan
  • Publication number: 20200354674
    Abstract: Embodiments of a method of modulating a potency level phenotype of a source population of cells include culturing the source cell population in a liquid medium within a cell culture incubator, the incubator is configured to independently regulate one or more variable parameters of gaseous conditions within the incubator, the more than one variable atmospheric parameters within the incubator being regulated independently of each other and independently of ambient external gaseous conditions. The method further includes regulating the one or more variable parameters of the gaseous condition within the incubator such that at least one of the one or more variable parameter differs from an ambient level of the respective variable parameter, and as a consequence of such difference from ambient conditions, the subset population is driven from a first potency level phenotype to a second potency level phenotype.
    Type: Application
    Filed: December 18, 2018
    Publication date: November 12, 2020
    Inventors: James LIM, Bruce ADAMS, Zack PAPPALARDO, Brian FETH
  • Publication number: 20200240819
    Abstract: Various aspects of this disclosure comprise systems and methods for synchronizing sensor data acquisition and/or output. For example, various aspects of this disclosure provide for achieving a desired level of timing accuracy in a MEMS sensor system, even in an implementation in which timer drift is substantial.
    Type: Application
    Filed: December 23, 2019
    Publication date: July 30, 2020
    Inventors: Andy Milota, James Lim, William Kerry Keal
  • Patent number: 10534014
    Abstract: A system and method for reliably detecting when a device has been dropped. In a non-limiting example, a drop detection system may be operable to perform one or more of: fall detection, end-of-fall detection, and/or detection of no motion after the fall. The drop detection system may, for example, analyze information from one or more MEMS sensors on-board the device to detect when the device has been dropped.
    Type: Grant
    Filed: August 21, 2014
    Date of Patent: January 14, 2020
    Assignee: InvenSense, Inc.
    Inventors: William Kerry Keal, James Lim
  • Patent number: 10514279
    Abstract: Various aspects of this disclosure comprise systems and methods for synchronizing sensor data acquisition and/or output. For example, various aspects of this disclosure provide for achieving a desired level of timing accuracy in a MEMS sensor system, even in an implementation in which timer drift is substantial.
    Type: Grant
    Filed: January 14, 2019
    Date of Patent: December 24, 2019
    Assignee: InvenSense, Inc.
    Inventors: Andy Milota, James Lim, William Kerry Keal
  • Publication number: 20190227093
    Abstract: A method includes generating motion data by receiving a gyroscope data from a gyroscope sensor, performing integration using the gyroscope data and generating an integrated gyroscope data using a first processor. The method further includes receiving a data from one or more sensors, other than the gyroscope sensor, and performing sensor fusion using the integrated gyroscope data and the data to generate motion data using a second processor.
    Type: Application
    Filed: April 1, 2019
    Publication date: July 25, 2019
    Inventors: William Kerry Keal, James Lim, Sinan Karahan
  • Patent number: 10353000
    Abstract: A multi-bit flip-flop includes: a single scan input pin to receive a scan input signal, a plurality of data input pins to receive first and second data input signals, a first scan flip-flop to select one of the scan input signal and the first data input signal as a first selection signal in response to a scan enable signal and to latch the first selection signal to provide a first output signal, a second scan flip-flop to select one of an internal signal corresponding to the first output signal and the second data input signal as a second selection signal in response to the scan enable signal and to latch the second selection signal to provide a second output signal, and a plurality of output pins to output the first and second output signals, wherein scan paths of the first and second scan flip-flops are connected to each other.
    Type: Grant
    Filed: April 5, 2017
    Date of Patent: July 16, 2019
    Assignee: Samsung Electronics Co., Ltd.
    Inventors: Doo-Seok Yoon, Min-Su Kim, Chung-Hee Kim, Dae-Seong Lee, Hyun Lee, Matthew Berzins, James Lim