Patents by Inventor James M. Felts

James M. Felts has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Separation of active .alpha..sub.1 -acid glycoprotein and utilization in the lipoprotein lipase enzyme system
    Patent number: 4264589
    Abstract: This invention relates to a method of separating the active .alpha..sub.1 -acid glycoprotein fraction, a co-factor in the lipoprotein lipase reaction, from urine of nephrotic animals and humans as follows:(a) concentrate the said urine to about 10-20% by volume;(b) precipitate undesired protein at pH 4 with ammonium sulfate; and(c) recover the .alpha..sub.1 -acid glycoprotein fraction from the supernatant, neutralize with solid NaHCO.sub.3, and purify by dialysis versus H.sub.2 O and lyophilize.This active .alpha..sub.1 -acid glycoprotein fraction is utilized in effective amounts in nephrotic animals to reverse the defect in triglyceride removal caused by the loss of plasma constituents in urine.
    Type: Grant
    Filed: July 17, 1979
    Date of Patent: April 28, 1981
    Inventors: James M. Felts, Ilona Staprans
  • Separation of active .alpha..sub.1 -acid glycoprotein and utilization in the lipoprotein lipase enzyme system
    Patent number: 4178285
    Abstract: This invention relates to a method of separating the active .alpha..sub.1 -acid glycoprotein fraction, a co-factor in the lipoprotein lipase reaction, from urine of nephrotic animals and humans as follows:(a) concentrate the said urine to about 10-20% by volume;(b) precipitate undesired protein at pH 4 with ammonium sulfate; and(c) recover the .alpha..sub.1 -acid glycoprotein fraction from the supernatant, neutralize with solid NaHCO.sub.3, and purify by dialysis versus H.sub.2 O and lyophilize.This active .alpha..sub.1 -acid glycoprotein fraction is utilized in effective amounts in nephrotic animals to reverse the defect in triglyceride removal caused by the loss of plasma constituents in urine.
    Type: Grant
    Filed: December 20, 1978
    Date of Patent: December 11, 1979
    Inventors: James M. Felts, Ilona Staprans