Patents by Inventor James M. Fortunato

James M. Fortunato has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4532333
    Abstract: The invention relates to 1-(aminoalkylphenyl and aminoalkylbenzyl)indoles and indolines of the formula: ##STR1## where R.sub.1 and R.sub.2 are the same or different and are hydrogen, lower alkyl, cycloalkyl and acyl of the formula ##STR2## where R.sub.3 is lower alkyl, lower alkoxy, cycloalkyl, phenyl of the formula ##STR3## and Ar lower alkyl of the formula -lower alkylene ##STR4## X is hydrogen, halogen, lower alkoxy, Ar lower alkoxy of the formula ##STR5## lower alkylene --O--; m and p are independently integers of 0 and 1 and the pharmaceutically acceptable acid addition salts thereof.
    Type: Grant
    Filed: August 6, 1984
    Date of Patent: July 30, 1985
    Assignee: Hoechst-Roussel Pharmaceuticals, Inc.
    Inventors: Edward J. Glamkowski, James M. Fortunato
  • Patent number: 4472414
    Abstract: There are described spiro[indolo[1,7-ab][1,5]benzodiazepine-2,4'-piperidines]of the formula ##STR1## wherein p is 1 or 0, R.sub.1 is hydrogen or methyl and R is hydrogen or --CO(CH.sub.2).sub.n NR.sub.2 R.sub.3, R.sub.2 and R.sub.3 being each hydrogen or methyl but at least one of the two being methyl, and n being 1 or 2, which are useful as analgesic agents; intermediate compounds therefor; and methods for synthesizing the foregoing compounds.
    Type: Grant
    Filed: May 18, 1983
    Date of Patent: September 18, 1984
    Assignee: Hoechst-Roussel Pharmaceuticals Incorporated
    Inventors: Edward J. Glamkowski, James M. Fortunato, Richard C. Allen
  • Patent number: 4448784
    Abstract: The invention relates to 1-(aminoalkylphenyl and aminoalkylbenzyl)indoles and indolines of the formula: ##STR1## where R.sub.1 and R.sub.2 are the same or different and are hydrogen, lower alkyl, cycloalkyl and acyl of the formula ##STR2## where R.sub.3 is lower alkyl, lower alkoxy, cycloalkyl, phenyl of the formula ##STR3## and Ar lower alkyl of the formula ##STR4## X is hydrogen, halogen, lower alkoxy, Ar lower alkoxy of the formula ##STR5## m and p are independently integers of 0 and 1 and the pharmaceutically acceptable acid addition salts thereof.
    Type: Grant
    Filed: April 12, 1982
    Date of Patent: May 15, 1984
    Assignee: Hoechst-Roussel Pharmaceuticals, Inc.
    Inventors: Edward J. Glamkowski, James M. Fortunato
  • Patent number: 4192874
    Abstract: What is disclosed are 1,2,6,7-tetrahydroindolo[1,7-ab] [1,5]benzodiazepines of the formula ##STR1## wherein R is hydrogen, loweralkyl, or cycloalkyl; ##STR2## n is an integer from 1 to 3; R.sub.1 is hydrogen, loweralkyl, or phenylloweralkyl;R.sub.2 is hydrogen or loweralkyl;or R.sub.1 and R.sub.2 may be taken together with the nitrogen to which they are attached to form pyrrolidinyl, piperidino, morpholino, or phenylpiperazinyl; andR.sub.3 is loweralkyl; and the pharmaceutically acceptable acid addition salts thereof.These compounds are useful as antidepressants and as analgesic and anti-inflammatory agents.
    Type: Grant
    Filed: November 2, 1978
    Date of Patent: March 11, 1980
    Assignee: American Hoechst Corporation
    Inventors: Edward J. Glamkowski, James M. Fortunato
  • Patent number: 4186199
    Abstract: What is disclosed are ##STR1## wherein X is hydrogen, halogen or trifluoromethyl;Y is hydrogen, halogen or trifluoromethyl;R is hydrogen, loweralkyl, cycloalkyl, phenyl, halophenyl, furyl, pyridinyl, 4-methylpiperazin-1-ylethyl or phenylloweralkyl;R.sup.1 is hydrogen;n and m are independently 0 or 1, but n is not 0 when m is 1, and the bonds between ring positions 1 and 2 and between positions 6 and 7 are respectively saturated when n and m are 1 and are unsaturated when n and m are 0;pharmaceutically acceptable acid addition salts thereof; methods of preparing said compounds; pharmaceutical compositions including said compounds; methods of treatment using the compounds; and intermediates therefor.These compounds are useful as analgesic and anti-inflammatory agents, as well as intermediates for the preparation of other pharmaceutically active compounds.
    Type: Grant
    Filed: November 2, 1978
    Date of Patent: January 29, 1980
    Assignee: American Hoechst Corporation
    Inventors: Edward J. Glamkowski, James M. Fortunato