Abstract: A method and apparatus for managing simulation results involves identifying distinct transactions in a group of simulation results so that the simulation results can be stored and viewed on a transaction basis instead of as a single continuous block of simulation results. A transaction is defined as a specific sequence of transitions on a selection or grouping of signals over a period of time where the signal activity has some higher level operational meaning. Simulation results are recorded on a transaction basis by storing standard simulation results information along with transaction-specific data elements, including the name of the transaction, the start time of the transaction, the end time of the transaction, and the interface on which the transaction takes place. Additional transaction-specific data elements may include parent and child relationships and predecessor and successor relationships between transactions.

Abstract: A method and apparatus for managing simulation results involve identifying errors within a group of simulation results so that the errors can be recorded into a database and viewed for analysis. In a preferred embodiment of the invention, distinct transactions within a group of simulation results are identified and recorded along with the identified errors. Recorded error-specific data and transaction-specific data are then utilized to graphically display the simulation results such that individual transactions identified within the simulation results are graphically distinct and such that errors occurring during a transaction are visually identified with the transaction. Recording and displaying error information and raising the level of abstraction of simulation results from cycles and signals to transactions enables easier simulation analysis and debugging.

Abstract: A delivery system for biologically active materials consisting of polysaccharide or polypeptide microspheres which bind to glycosaminoglycan receptors on cell surfaces. The delivery system can be used to localize drugs by both biochemical and physical means. In one embodiment, microspheres prepared from the polysaccharide chitosan are bound to anionic polysaccharides similar to the glycosaminoglycan receptors found on the surface of capillary endothelial cells. The microspheres were formulated to have a controlled cationic character, and had a mean diameter of 0.70 u and a magnetite content of 16% w/w. Binding to a model polysaccharide, heparin, was demonstrated in vitro. Binding to cultured cerebral capillary endothelial cells was also demonstrated.