Abstract: A method for the storage of biological samples is disclosed. The method includes the steps of coupling a storage device to a biological sample collection apparatus capable of collecting a biological sample from a subject, introducing a biological sample from the biological sample collection apparatus to the storage device, and drying the biological sample on the storage device. In another embodiment, the storage device used by the method may include a collection medium having a top surface, a bottom surface, and a predetermined size and shape, the top surface comprising a position marker and at least one binding site operable to bind a biological sample; and a protective facing substantially impermeable to the biological sample, the protective facing coupled to the top surface of the collection medium and having a size and shape substantially similar to the predetermined size and shape of the collection medium.

Abstract: A method for delivering a fluid to an animal with a drug delivery device without causing contamination to the drug delivery device. The drug delivery device used by the method may comprise a fluid subsystem with a switching device, disposable syringes, fluid reservoirs, disposable tubing, and a catheter. In one embodiment, the method allows a user to deliver multiple drugs to an animal without contaminating the valves that control the flow of fluid.

Abstract: A tube assembly, system and method for biological sample collection. In one embodiment, the tube assembly of the present disclosure includes a first tube, a second tube, a mechanism for securing the first and second tubes. The securing mechanism orients the first ends of the first and second tubes in a manner such that the first end of the second tube extends beyond the first end of the first tube to create an interstitial space between the outer diameter of the first tube and the inner diameter of the second tube.

Abstract: A method for the storage of biological samples is disclosed. The method includes the steps of coupling a storage device to a biological sample collection apparatus capable of collecting a biological sample from a subject, introducing a biological sample from the biological sample collection apparatus to the storage device, and drying the biological sample on the storage device. In another embodiment, the storage device used by the method may include a collection medium having a top surface, a bottom surface, and a predetermined size and shape, the top surface comprising a position marker and at least one binding site operable to bind a biological sample; and a protective facing substantially impermeable to the biological sample, the protective facing coupled to the top surface of the collection medium and having a size and shape substantially similar to the predetermined size and shape of the collection medium.

Abstract: Devices, systems, and methods for the collection of biological samples. In at least one exemplary embodiment, a device comprises a collection medium having top and bottom surfaces and a predetermined size and shape, the top surface comprising a position marker and at least one binding site operable to bind a biological sample, a protective facing substantially impermeable to the biological sample, the protective facing coupled to the top surface of the collection medium and having a size and shape substantially similar to the predetermined size and shape of the collection medium. The protective facing being sized and shaped to define a first void positioned to allow for the transfer of the biological sample through the protective facing and onto the at least one binding site of the collection medium, and a second void positioned to expose the position marker for alignment of the collection medium.

Abstract: A method for delivering a fluid to an animal with a drug delivery device without causing contamination to the drug delivery device. The drug delivery device used by the method may comprise a fluid subsystem with a switching device, disposable syringes, fluid reservoirs, disposable tubing, and a catheter. In one embodiment, the method allows a user to deliver multiple drugs to an animal without contaminating the valves that control the flow of fluid.

Abstract: A method for delivering a fluid to an animal with a drug delivery device without causing contamination to the drug delivery device. The drug delivery device used by the method may comprise a fluid subsystem with a switching device, disposable syringes, fluid reservoirs, disposable tubing, and a catheter. In one embodiment, the method allows a user to deliver multiple drugs to an animal without contaminating the valves that control the flow of fluid.

Abstract: Devices, systems, and methods for the collection of biological samples. In at least one exemplary embodiment, a device comprises a collection medium having top and bottom surfaces and a predetermined size and shape, the top surface comprising a position marker and at least one binding site operable to bind a biological sample, a protective facing substantially impermeable to the biological sample, the protective facing coupled to the top surface of the collection medium and having a size and shape substantially similar to the predetermined size and shape of the collection medium. The protective facing being sized and shaped to define a first void positioned to allow for the transfer of the biological sample through the protective facing and onto the at least one binding site of the collection medium, and a second void positioned to expose the position marker for alignment of the collection medium.

Abstract: A tube assembly, system and method for biological sample collection. In one embodiment, the tube assembly of the present disclosure includes a first tube, a second tube, a mechanism for securing the first and second tubes.

Abstract: A drug delivery device that utilizes a fluid subsystem with a switching device to deliver multiple drugs to an animal without causing contamination. The fluid subsystem can further comprise disposable syringes, fluid reservoirs, disposable tubing and a catheter. In the embodiments that utilize multiple disposable syringes, the drug delivery device allows a user to deliver multiple drugs to an animal through a catheter without contaminating the switching devices that control the flow of fluid. The drug delivery device can further utilize a controller to control the switching devices and a controller and syringe pumps to control the operation of the syringes.

Abstract: A method for delivering a fluid to an animal with a drug delivery device without causing contamination to the drug delivery device. The drug delivery device used by the method may comprise a fluid subsystem with a switching device, disposable syringes, fluid reservoirs, disposable tubing, and a catheter. In one embodiment, the method allows a user to deliver multiple drugs to an animal without contaminating the valves that control the flow of fluid.

Abstract: A drug delivery device that utilizes a fluid subsystem with a switching device to deliver multiple drugs to an animal without causing contamination. The fluid subsystem can further comprise disposable syringes, fluid reservoirs, disposable tubing and a catheter. In the embodiments that utilize multiple disposable syringes, the drug delivery device allows a user to deliver multiple drugs to an animal through a catheter without contaminating the switching devices that control the flow of fluid. The drug delivery device can further utilize a controller to control the switching devices and a controller and syringe pumps to control the operation of the syringes.

Abstract: A movement-responsive system for conducting tests on freely-moving animals is disclosed. The invention includes a container for housing the animal, a mechanism for rotating the container in response to rotational movement of the animal, and one or more test leads connected to the animal for performance of biomedical tests such as infusion, in vivo ultrafiltration, laser-doppler monitoring of blood flow, electrical stimulation and in vivo microdialysis, and a method for automated micro sampling of body fluids in free-moving animals. Because the cage is rotated in response to the animal's rotational movement, no swivel connectors are needed. A rotational sensor assembly is provided to detect rotational movement of the animal within the container. A vertical sensor assembly is mounted to the counterbalanced arm for monitoring vertical movements of the animal. The outputs of the sensor assemblies are routed to a computer or other device for monitoring and/or analyzing the activity of the animal.