Patents by Inventor James M. Murray

James M. Murray has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230265315
    Abstract: Two-part silane modified polymer/free radically curable adhesive systems demonstrating improved strength and percent elongation are provided.
    Type: Application
    Filed: January 3, 2023
    Publication date: August 24, 2023
    Inventors: Chih-Min Cheng, Jian Lin, Christopher J. Verosky, James M. Murray, Daniel Yi, Richard Corrao, Zachary S. Bauman, Ling Li
  • Publication number: 20220305091
    Abstract: The invention relates to dose escalation enzyme replacement therapy using acid sphingomyelinase (ASM) for the treatment of human subjects having acid sphingomyelinase deficiency (ASMD), and, in particular, patients with non-neurological manifestations of Niemann-Pick Disease (NPD), and in certain embodiments, NPD type B.
    Type: Application
    Filed: February 18, 2022
    Publication date: September 29, 2022
    Applicants: ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, GENZYME CORPORATION
    Inventors: Edward H. Schuchman, Robert J. Desnick, Gerald F. Cox, Laura P. Andrews, James M. Murray
  • Publication number: 20210077593
    Abstract: The invention relates to dose escalation enzyme replacement therapy using acid sphingomyelinase (ASM) for the treatment of human subjects having acid sphingomyelinase deficiency (ASMD), and, in particular, patients with non-neurological manifestations of Niemann-Pick Disease (NPD), and in certain embodiments, NPD type B.
    Type: Application
    Filed: May 26, 2020
    Publication date: March 18, 2021
    Applicants: ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, GENZYME CORPORATION
    Inventors: Edward H. Schuchman, Robert J. Desnick, Gerald F. Cox, Laura P. Andrews, James M. Murray
  • Publication number: 20190151419
    Abstract: The invention relates to dose escalation enzyme replacement therapy using acid sphingomyelinase (ASM) for the treatment of human subjects having acid sphingomyelinase deficiency (ASMD), and, in particular, patients with non-neurological manifestations of Niemann-Pick Disease (NPD), and in certain embodiments, NPD type B.
    Type: Application
    Filed: December 4, 2018
    Publication date: May 23, 2019
    Applicants: ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI, GENZYME CORPORATION
    Inventors: Edward H. Schuchman, Robert J. Desnick, Gerald F. Cox, Laura P. Andrews, James M. Murray
  • Patent number: 10188705
    Abstract: The invention relates to dose escalation enzyme replacement therapy using acid sphingomyelinase (ASM) for the treatment of human subjects having acid sphingomyelinase deficiency (ASMD), and, in particular, patients with non-neurological manifestations of Niemann-Pick Disease (NPD), and in certain embodiments, NPD type B.
    Type: Grant
    Filed: April 12, 2017
    Date of Patent: January 29, 2019
    Assignees: Icahn School of Medicine at Mount Sinai, Genzyme Corporation
    Inventors: Edward H. Schuchman, Robert J. Desnick, Gerald F. Cox, Laura P. Andrews, James M. Murray
  • Publication number: 20180055916
    Abstract: The invention relates to dose escalation enzyme replacement therapy using acid sphingomyelinase (ASM) for the treatment of human subjects having acid sphingomyelinase deficiency (ASMD), and, in particular, patients with non-neurological manifestations of Niemann-Pick Disease (NPD), and in certain embodiments, NPD type B.
    Type: Application
    Filed: April 12, 2017
    Publication date: March 1, 2018
    Applicants: Icahn School of Medicine at Mount Sinai, Genzyme Corporation
    Inventors: Edward H. Schuchman, Robert J. Desnick, Gerald F. Cox, Laura P. Andrews, James M. Murray
  • Patent number: 9655954
    Abstract: The invention relates to dose escalation enzyme replacement therapy using acid sphingomyelinase (ASM) for the treatment of human subjects having acid sphingomyelinase deficiency (ASMD), and, in particular, patients with non-neurological manifestations of Niemann-Pick Disease (NPD), and in certain embodiments, NPD type B.
    Type: Grant
    Filed: July 8, 2015
    Date of Patent: May 23, 2017
    Assignees: Icahn School of Medicine at Mount Sinai, Genzyme Corporation
    Inventors: Edward H. Schuchman, Robert J. Desnick, Gerald F. Cox, Laura P. Andrews, James M. Murray
  • Publication number: 20160120957
    Abstract: The invention relates to dose escalation enzyme replacement therapy using acid sphingomyelinase (ASM) for the treatment of human subjects having acid sphingomyelinase deficiency (ASMD), and, in particular, patients with non-neurological manifestations of Niemann-Pick Disease (NPD), and in certain embodiments, NPD type B.
    Type: Application
    Filed: July 8, 2015
    Publication date: May 5, 2016
    Applicants: GENZYME CORPORATION, ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
    Inventors: Edward H. Schuchman, Robert J. Desnick, Gerald F. Cox, Laura P. Andrews, James M. Murray
  • Patent number: 9114139
    Abstract: The invention relates to dose escalation enzyme replacement therapy using acid sphingomyelinase (ASM) for the treatment of human subjects having acid sphingomyelinase deficiency (ASMD), and, in particular, patients with non-neurological manifestations of Niemann-Pick Disease (NPD), and in certain embodiments, NPD type B.
    Type: Grant
    Filed: January 16, 2014
    Date of Patent: August 25, 2015
    Assignees: Icahn School of Medicine at Mount Sinai, Genzyme Corporation
    Inventors: Edward H. Schuchman, Robert J. Desnick, Gerald F. Cox, Laura P. Andrews, James M. Murray
  • Publication number: 20140335070
    Abstract: The invention relates to dose escalation enzyme replacement therapy using acid sphingomyelinase (ASM) for the treatment of human subjects having acid sphingomyelinase deficiency (ASMD), and, in particular, patients with non-neurological manifestations of Niemann-Pick Disease (NPD), and in certain embodiments, NPD type B.
    Type: Application
    Filed: January 16, 2014
    Publication date: November 13, 2014
    Applicants: Genzyme Corporation, Icahn School of Medicine at Mount Sinai
    Inventors: Edward H. Schuchman, Robert J. Desnick, Gerald F. Cox, Laura P. Andrews, James M. Murray
  • Patent number: 8709408
    Abstract: The invention relates to dose escalation enzyme replacement therapy using acid sphingomyelinase (ASM) for the treatment of human subjects having acid sphingomyelinase deficiency (ASMD), and, in particular, patients with non-neurological manifestations of Niemann-Pick Disease (NPD), and in certain embodiments, NPD type B.
    Type: Grant
    Filed: November 16, 2012
    Date of Patent: April 29, 2014
    Assignees: Icahn School of Medicine at Mount Sinai, Genzyme Corporation
    Inventors: Edward H. Schuchman, Robert J. Desnick, Gerald F. Cox, Laura P. Andrews, James M. Murray
  • Patent number: 8658162
    Abstract: The invention relates to dose escalation enzyme replacement therapy using acid sphingomyelinase (ASM) for the treatment of human subjects having acid sphingomyelinase deficiency (ASMD), and, in particular, patients with non-neurological manifestations of Niemann-Pick Disease (NPD), and in certain embodiments, NPD type B.
    Type: Grant
    Filed: November 16, 2012
    Date of Patent: February 25, 2014
    Assignees: Icahn School of Medicine at Mount Sinai, Genzyme Corporation
    Inventors: Edward H. Schuchman, Robert J. Desnick, Gerald F. Cox, Laura P. Andrews, James M. Murray
  • Patent number: 8349319
    Abstract: The invention relates to dose escalation enzyme replacement therapy using acid sphingomyelinase (ASM) for the treatment of human subjects having acid sphingomyelinase deficiency (ASMD), and, in particular, patients with non-neurological manifestations of Niemann-Pick Disease (NPD), and in certain embodiments, NPD type B.
    Type: Grant
    Filed: August 28, 2010
    Date of Patent: January 8, 2013
    Assignees: Mount Sinai School of Medicine, Genzyme Corporation
    Inventors: Edward H. Schuchman, Robert J. Desnick, Gerald F. Cox, Laura P. Andrews, James M. Murray
  • Publication number: 20110052559
    Abstract: The invention relates to dose escalation enzyme replacement therapy using acid sphingomyelinase (ASM) for the treatment of human subjects having acid sphingomyelinase deficiency (ASMD), and, in particular, patients with non-neurological manifestations of Niemann-Pick Disease (NPD), and in certain embodiments, NPD type B.
    Type: Application
    Filed: August 28, 2010
    Publication date: March 3, 2011
    Inventors: Edward H. Schuchman, Robert J. Desnick, Gerald F. Cox, Laura P. Andrews, James M. Murray
  • Patent number: 5421113
    Abstract: A product information display tag for providing product information at the forward end of a horizontal product support hook has a mounting portion for attaching the tag to the rearward end of the hook, an elongate intermediate portion to extend over and along the hook and a label holder at the forward end of the intermediate portion. The mounting portion and intermediate portion are formed together as an integral plastic extrusion with a female grip at the forward end of the intermediate portion to attach the label holder. The label holder is formed as a coextrusion of a label holder panel in a rigid plastic material and a bead along one edge of the panel in a flexible plastic to fit in the grip at the forward end of the intermediate portion. The bead forms a hinge at the front end of the tag enabling the label holding panel to be raised and facilitate removal of articles from the hook.
    Type: Grant
    Filed: February 28, 1994
    Date of Patent: June 6, 1995
    Assignee: FEMC Ltd.
    Inventors: John Gebka, James M. Murray
  • Patent number: 4021088
    Abstract: An installation in a dish washing machine to lower a limp mesh on dishes loaded in each work-basket thereof, such mesh settling on and between the dishes during the rearward travel of the work-basket to stabilize the dishes during the dish washing operation. The installation involves a horizontal looped drive operated by each work-basket and a mesh-supporting conveyor companion to and actuated by the said drive. The mesh is attached at the rear to the conveyor, and with its front end to the work-basket. It is drawn by and over the work-basket on the rearward travel thereof; and the conveyor has an overdrive to advance the mesh with sufficient slack to settle as stated.
    Type: Grant
    Filed: April 7, 1976
    Date of Patent: May 3, 1977
    Inventor: James M. Murray
  • Patent number: 4014126
    Abstract: An attachment for fishing rods for the slingshot casting of the fishing line. The attachment is clamped to the fishing rod and extends forwardly with pivoted spring arms. When these are swung back to vertical position they become fixed; and the elastic sling extends rearwardly from the same. The arms are also swingable downwardly to lock as props for supporting the fishing rod on the ground or on the deck of a boat.
    Type: Grant
    Filed: March 26, 1976
    Date of Patent: March 29, 1977
    Assignee: Wiley H. Samuels
    Inventors: Wiley H. Samuels, James M. Murray
  • Patent number: 4006950
    Abstract: A mesh adapted to be lowered on a group of dishes contained in a work-basket of a dish washing machine. The mesh is limp and drapes from its weight over and around the dishes to maintain them as deposited and apart from each other. A mechanized application locates the mesh overhead in the dish washing machine, and causes it to be lowered automatically as stated on the insertion of the dish-loaded work-basket into the machine and raised back to the overhead position on the withdrawal of the work-basket.
    Type: Grant
    Filed: February 14, 1975
    Date of Patent: February 8, 1977
    Inventor: James M. Murray
  • Patent number: 3988048
    Abstract: A mesh adapted to be lowered on a group of dishes distributed in the work basket of a dish washing machine. The mesh is composed of crossed strands which are loose and render the mesh limp. The mesh is fitted with a distribution of soft-surfaced weights which depress sections of the mesh to fill spaces between the dishes and drape around them, checking dishes from upsetting or colliding during the dish washing operation.
    Type: Grant
    Filed: September 23, 1974
    Date of Patent: October 26, 1976
    Inventor: James M. Murray
  • Patent number: 3982799
    Abstract: Upper and lower mesh-units are installed in a dish washing machine above the spaces into which work-baskets containing dishes to be washed are insertible when the door of the machine is open. A mechanism between the door and the mesh units allows them to descend into the work-baskets as the door is closed. The meshes carried by the mesh-units then drape over and between the dishes to hold them apart and against turning during the dish washing operation.
    Type: Grant
    Filed: May 27, 1975
    Date of Patent: September 28, 1976
    Inventor: James M. Murray