Abstract: An optical metasurface film includes a flexible polymeric film having a first major surface, a patterned polymer layer having a first surface proximate to the first major surface of the flexible polymeric film and having a second nanostructured surface opposite the first surface, and a refractive index contrast layer adjacent to the nanostructured surface of the patterned polymer layer forming a nanostructured bilayer with a nanostructured interface. The nanostructured bilayer acts locally on amplitude, phase, or polarization of light, or a combination thereof and imparts a light phase shift that varies as a function of position of the nano structured bilayer on the flexible polymeric film. The light phase shift of the nanostructured bilayer defines a predetermined operative phase profile of the optical metasurface film.

Abstract: Processes, compositions, and apparatus are disclosed. A first process includes providing a cyclopropenimine (CPI). A second process includes providing 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU). The first and second processes include reacting the CPI and DBU, respectively, with carbon dioxide (CO2) in the presence of a nucleophilic species (NuH) and releasing CO2 from products of the reactions by heating to a temperature below about 120° C. A process of direct air capture includes obtaining atmospheric CO2, reacting the CO2 with an organic base having an imine moiety to form a NuCO2? salt, and heating the NuCO2? salt to a temperature below about 120° C. A composition for low-temperature CO2 release includes a tris(amino)cyclopropenium (TAC+) ion and NuCO2?. An apparatus includes a component configured to provide a composition, including a CPI, for capturing CO2 and a component configured to release the CO2 by heating a to a temperature below 120° C.

Abstract: The present invention is related to processes for preparing ruxolitinib, or a salt thereof, and related synthetic intermediates related thereto.

Abstract: The present invention is related to processes for preparing ruxolitinib, or a salt thereof, and related synthetic intermediates related thereto.

Abstract: The present application provides processes for preparing 4-[3-(cyanomethyl)-3-(3?,5?-dimethyl-1H, 1?H-4,4?-bipyrazol-1-yl)azetidin-1-yl]-2,5-difluoro-N-[(1S)-2,2,2-trifluoro-1-methylethyl]benzamide, and phosphoric acid salt thereof, which is useful as a selective (Janus kinase 1) JAK1 inhibitor, as well as salt forms and intermediates related thereto.

Abstract: The present invention is related to processes for preparing ruxolitinib, or a salt thereof, and related synthetic intermediates related thereto.

Abstract: The present application provides processes for preparing 4-[3-(cyanomethyl)-3-(3?,5?-dimethyl-1H, 1?H-4,4?-bipyrazol-1-yl)azetidin-1-yl]-2,5-difluoro-N-[(1S)-2,2,2-trifluoro-1-methylethyl]benzamide, and phosphoric acid salt thereof, which is useful as a selective (Janus kinase 1) JAK1 inhibitor, as well as salt forms and intermediates related thereto.

Abstract: A vehicle trim component includes a trim body, with a primary fastener extending from the trim body. The primary fastener includes a first end and a second end. The first end includes a push clip head that is configured to substantially fit and project through an aperture in the vehicle panel. The second end is connected to the trim body. The secondary fastener is rotatably connected to the trim body by a living hinge and is positioned to engage the vehicle panel at an edge portion of the vehicle panel.

Abstract: A vehicle trim component includes a trim body, with a primary fastener extending from the trim body. The primary fastener includes a first end and a second end. The first end includes a push clip head that is configured to substantially fit and project through an aperture in the vehicle panel. The second end is connected to the trim body. The secondary fastener is rotatably connected to the trim body by a living hinge and is positioned to engage the vehicle panel at an edge portion of the vehicle panel.

Abstract: Coastal stabilization with multiple flow control of water to and from foraminous pipes and adjacent subsoil. Offshore underwater subsoil is fluidized by injection of water via underlying foraminous piping, thereby increasing the concentration of subsoil suspended in the overlying water during its onrush onto the shore. Under normal conditions beach subsoil is dewatered by withdrawing water therefrom via adjacent foraminous piping, and under stormy conditions subsoil further onshore is dewatered via foraminous piping adjacent thereto, inducing deposition of the suspended subsoil onto the adjacent land. Water collected by such dewatering can be stored temporarily and be discharged by use in such fluidization or be discharged to the sea.

Abstract: Horizontal foraminous piping is placed in non-cohesive subsoil by means of an upright engaged disengageably at its bottom end to the top end of an open-ended hollow upright stanchion. Fluid jetted into the top end of the placement pipe and out of the bottom end of the stanchion to fluidize subjacent subsoil enables the pipe to be pressed downward until the stanchion reaches a desired depth. With an end of the cable attached thereto, winding up of the cable draws the foraminous piping to the stanchion, while fluid jetted from the horizontal foraminous piping downward onto and into subjacent subsoil to fluidize it enables the piping to move down into and laterally within the subsoil, for attachment to the stanchion. The placement pipe is disengaged and removed--but may be reattached to facilitate subsequent removal of the stanchion and the piping, usually with fluidizing flow from the piping into adjacent subsoil.

Abstract: Monitoring fluidized flow of underwater non-cohesive subsoil. Fluid is jetted, as from a horizontal array of foraminous piping, into subjacent subsoil to fluidize it and preferably to transport it in an overhead lateral direction. Sensors at sites throughout the array monitor flows intercepted by vanes on stems upstanding from the array and transmit resulting data to a control system adapted to render the jetting intermittent, sequential, and of given durations.

Abstract: The wheel cylinder retainer clip applying tool is a plier-like hand tool with widely spaces angularly related jaws that are oriented perpendicularly to the handles. At the tips of the jaws are opposed cylindrical grippers that are oriented on perpendicular axes. A first jaw is mounted on a spacer which extends outward from a pivot opposite a first handle. A second jaw extends outward from the pivot perpendicularly to a second handle. The second jaw has a semi-cylindrical cradle at its outer end for spporting the wheel cylinder body. The cradle is oriented around an axis parallel to the pivot axis. The first jaw has a high aspect ratio cylinder at the outer end, with a greater length than diameter. The cylinder is oriented at a slight angle outward from a direction parallel with the first handle.

Abstract: Beach stabilization with multiple flow control of water to and from foraminous pipes and adjacent subsoil. Offshore underwater subsoil is fluidized by injection of water via underlying foraminous piping, thereby increasing the concentration of subsoil suspended in the overlying water during its onrush onto the shore. Under normal conditions beach subsoil is dewatered by withdrawing water therefrom via adjacent foraminous piping, and under stormy conditions subsoil further onshore is dewatered via foraminous piping adjacent thereto, inducing deposition of the suspended subsoil onto the adjacent land. Water collected by such dewatering can be used in such fluidization.

Abstract: Segmented fluidization of underwater subsoils in a manner resembling peristalsis. An array of underwater locations is selected, and water is injected into the subsoil, preferably in a pattern of sequence and duration to generate lateral flow of fluidized subsoil. Apparatus for practicing such method includes a water supply pipe, multiple water-jetting branch tubes interconnected to respective segments of the supply pipe, each such branch tube being individually valved at its junction thereto. Valve-control apparatus is provided to open and close the respective valves at given times and for given durations, as by pre-programming, or optionally controlled according to resulting flow and/or pressure monitored by nearby sensors.

Abstract: Fluidization-assisted beach stabilization. Water is collected from beach-underlying subsoil, and is used to fluidize adjacent off-shore subsoil. More particularly, a first foraminous pipe is buried in beach-underlying subsoil, a second foraminous pipe is buried in adjacent offshore subsoil, such pipes are interconnected, water is collected from the beach subsoil in the first pipe, is transported through the interconnecting pipe to the second pipe, and is jetted from the latter pipe to fluidize the offshore subsoil therewith. Such apparatus and method make more wave-suspended subsoil particles available for deposition onto the beach and for retention thereon.

Abstract: Placement of foraminous dual piping in non-cohesive subsoil, and use in beach stabilization or use in fluidization as navigation channel maintenance. Air, water, or mixed fluid medium is jetted from the foraminous piping downward onto and into such subsoil so as to fluidize it, while the piping is pressed downward, as by earth anchors, into the fluidized subsoil until it is below the level of adjacent subsoil located apart from the fluidization vicinity. A zigzag arrangement of flanking earth anchors as viewed from above and interconnected by tie bars from earth anchor to adjacent earth anchor in the pattern.