Patents by Inventor James M. Spitler

James M. Spitler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240277350
    Abstract: An apparatus, system, and method are disclosed for remediating a condition present in a patient. In some implementations, the apparatus may include a body. Also, the apparatus may include a bone attachment feature. Furthermore, the apparatus may include a first resection feature configured to guide a first osteotomy of a donor bone. In addition, the apparatus may include a second resection feature configured to guide a second osteotomy of the donor bone, the second osteotomy offset from the first resection feature by a dimension that satisfies a predefined bone graft dimension.
    Type: Application
    Filed: February 21, 2024
    Publication date: August 22, 2024
    Inventors: James Q. Spitler, Lee M. Hlad, Adam D. Perler, Andrew C. Khan
  • Patent number: 12042393
    Abstract: An expandable intervertebral implant is disclosed for use in between adjacent vertebral bodies in a spine. An expandable intervertebral implant may include an upper plate having a first upper side and a second upper side, a lower plate having a first lower side, a second lower side, and a first lattice that connects the first upper side to the first lower side. The expandable intervertebral implant may further include a second lattice that connects the second upper side of the upper plate to the second lower side of the lower plate and an opening having a longitudinal axis between the upper plate, lower plate, first lattice, and second lattice. The expandable intervertebral implant may further include an expansion mechanism comprising a driver that expands the upper plate and the lower plate away from each other along a cephalad-caudal axis by deforming the first lattice and the second lattice.
    Type: Grant
    Filed: December 21, 2020
    Date of Patent: July 23, 2024
    Assignee: FloSpine, LLC
    Inventors: James Q. Spitler, Peter M. Harris
  • Publication number: 20240238015
    Abstract: Systems and methods are disclosed for maintaining spacing between a superior spinous process and a superior lamina, and an inferior spinous process and an inferior lamina of adjacent vertebrae of a spine. A system may include an implant having a proximal superior surface with a superior concavity shaped to receive the superior spinous process, a proximal inferior surface with an inferior concavity shaped to receive the inferior spinous process, a distal superior surface, distal to the proximal superior surface, that faces the superior lamina, and a distal inferior surface, distal to the proximal inferior surface, that faces the inferior lamina. The implant may further have a threaded member extending along a proximal-distal direction, that rotates to urge the implant to move from a retracted configuration to a deployed configuration by urging the distal superior surface and the distal inferior surface to move apart.
    Type: Application
    Filed: March 30, 2024
    Publication date: July 18, 2024
    Applicant: FloSpine, LLC
    Inventors: Cheng-Lun SOO, Peter M. HARRIS, Robert BOMBACH, James Q. SPITLER, Luis A. ESCOBAR, III
  • Patent number: 7718702
    Abstract: There are disclosed compounds of the formula a prodrug thereof, or a pharmaceutically acceptable salt, solvate or stereoisomer of the compound or of said prodrug; which exhibit anti-inflammatory and immunodulatory activity. Also disclosed are pharmaceutical compositions containing said compounds and methods of using the compounds for the treatment of various diseases and conditions.
    Type: Grant
    Filed: August 15, 2005
    Date of Patent: May 18, 2010
    Assignee: Schering Corporation
    Inventors: Joseph A. Kozlowski, Neng-Yang Shih, Brian J. Lavey, Razia K. Rizvi, Bandarpalle B. Shankar, James M. Spitler, Ling Tong, Ronald L. Wolin, Michael K. Wong
  • Patent number: 7507767
    Abstract: There are disclosed compounds of the formula a prodrug thereof, or a pharmaceutically acceptable salt, solvate or stereoisomer of the compound or of said prodrug; which exhibit anti-inflammatory and immunodulatory activity. Also disclosed are pharmaceutical compositions containing said compounds and methods of using the compounds for the treatment of various diseases and conditions.
    Type: Grant
    Filed: February 6, 2002
    Date of Patent: March 24, 2009
    Assignee: Schering Corporation
    Inventors: Joseph A. Kozlowski, Neng-Yang Shih, Brian J. Lavey, Razia K. Rizvi, Bandarpalle B. Shankar, James M. Spitler, Ling Tong, Ronald L. Wolin, Michael K. Wong
  • Patent number: 7067539
    Abstract: The invention relates to compounds of the formula a prodrug thereof, or a pharmaceutically acceptable salt, solvate or stereoisomer of the compound or of said prodrug; which exhibit anti-inflammatory and immunodulatory activity. Also disclosed are pharmaceutical compositions containing said compounds and methods of using the compounds for the treatment of various diseases and conditions.
    Type: Grant
    Filed: August 7, 2002
    Date of Patent: June 27, 2006
    Assignee: Schering Corporation
    Inventors: Joseph A. Kozlowski, Neng-Yang Shih, Brian J. Lavey, Razia K. Rizvi, Bandarpalle B. Shankar, James M. Spitler, Ling Tong, Ronald L. Wolin, Michael K. Wong
  • Publication number: 20030232859
    Abstract: The invention relates to compounds of the formula 1
    Type: Application
    Filed: August 7, 2002
    Publication date: December 18, 2003
    Applicant: Schering Corporation
    Inventors: Joseph A. Kozlowski, Neng-Yang Shih, Brian J. Lavey, Razia K. Rizvi, Bandarpalle B. Shankar, James M. Spitler, Ling Tong, Ronald L. Wolin, Michael K. Wong
  • Publication number: 20030096844
    Abstract: There are disclosed compounds of the formula 1
    Type: Application
    Filed: February 6, 2002
    Publication date: May 22, 2003
    Applicant: Schering Corporation
    Inventors: Joseph A. Kozlowski, Neng-Yang Shih, Brian J. Lavey, Razia K. Rizvi, Bandarpalle B. Shankar, James M. Spitler, Ling Tong, Ronald L. Wolin, Michael K. Wong
  • Patent number: 5840725
    Abstract: Compound represented by the structural formula ##STR1## or a pharmaceutically acceptable salt thereof, wherein: a is 0, 1, 2 or3;b, d and e are independently 0, 1 or 2;R is H, C.sub.1-6 alkyl, --OH or C.sub.2 -C.sub.6 hydroxyalkyl;A is an optionally substituted oxime, hydrazone or olefin;X is a bond, --C(O)--, --O--, --NR.sup.6 --, --S(O)e--, --N(R.sup.6)C(O)--, --C(O)N(R.sup.6)-- --OC(O)NR.sup.6 --, --OC(.dbd.S)NR.sup.6 --, --N(R.sup.6)C(.dbd.S)O--, --C(.dbd.NOR.sup.1)--, --S(O).sub.2 N(R.sup.6)--, --N(R.sup.6)S(O).sub.2 --, --N(R.sup.6)C(O)O-- or --OC(O)--;T is H, phthalimidyl, aryl, heterocycloalkyl, heteroaryl, cycloalkyl or bridged cycloalkyl;Q is --SR.sup.6, --N(R.sup.6)(R.sup.7), --OR.sup.6, phenyl, naphthyl or heteroaryl;R.sup.6a, R.sup.7a, R.sup.8a, R.sup.9a, R.sup.6 and R.sup.7 are H, C.sub.1-6 alkyl, C.sub.2 -C.sub.6 hydroxyalkyl, C.sub.1 -C.sub.6 alkoxy-C.sub.1 -C.sub.6 alkyl, phenyl or benzyl; or R.sup.6 and R.sup.7, together with the nitrogen to which they are attached, form a ring;R.sup.
    Type: Grant
    Filed: July 25, 1997
    Date of Patent: November 24, 1998
    Assignee: Schering Corporation
    Inventors: Gregory A. Reichard, Robert G. Aslanian, Cheryl A. Alaimo, Michael P. Kirkup, Andrew Lupo, Jr., Pietro Mangiaracina, Kevin D. McCormick, John J. Piwinski, Bandarpalle B. Shankar, Neng-Yang Shih, James M. Spitler, Pauline C. Ting, Ashit Ganguly, Nicholas I. Carruthers
  • Patent number: 5696267
    Abstract: Compound represented by the structural formula ##STR1## or a pharmaceutically acceptable salt thereof, wherein: a is 0, 1, 2 or 3;b, d and e are independently 0, 1 or 2;R is H, C.sub.1-6 alkyl, --OH or C.sub.2 -C.sub.6 hydroxyalkyl;A is an optionally substituted oxime, hydrazone or olefin;X is a bond, --C(O)--, --O--, --NR.sup.6 --, --S(O).sub.e --, --N(R.sup.6)C(O)--, --C(O)N(R.sup.6)--OC(O)NR.sup.6 --, --OC(.dbd.S)NR.sup.6 --, --N(R.sup.6)C(.dbd.S)O--, --C(.dbd.NOR.sup.1)--, --S(O).sub.2 N(R.sup.6)--, --N(R.sup.6)S(O).sub.2 --,--N(R.sup.6)C(O)O-- or --OC(O)--;T is H, phthalimidyl, aryl, heterocycloalkyl, heteroaryl, cycloalkyl or bridged cycloalkyl;Q is --SR.sup.6, --N(R.sup.6)(R.sup.7), --OR.sup.6, phenyl, naphthyl or heteroaryl;R.sup.6a, R.sup.7a, R.sup.8a, R.sup.9a, R.sup.6 and R.sup.7 are H, C.sub.1-6 alkyl, C.sub.2 -C.sub.6 hydroxyalkyl, C.sub.1 -C.sub.6 alkoxy-C.sub.1 -C.sub.6 alkyl, phenyl or benzyl; or R.sup.6 and R.sup.7, together with the nitrogen to which they are attached, form a ring;R.sup.
    Type: Grant
    Filed: April 30, 1996
    Date of Patent: December 9, 1997
    Assignee: Schering Corporation
    Inventors: Gregory A. Reichard, Robert G. Aslanian, Cheryl A. Alaimo, Michael P. Kirkup, Andrew Lupo, Jr., Pietro Mangiaracina, Kevin D. McCormick, John J. Piwinski, Bandarpalle B. Shankar, Neng-Yang Shih, James M. Spitler, Pauline C. Ting, Ashit Ganguly, Nicholas I. Carruthers