Abstract: Disclosed are methods and systems for solid phase transfer of a reagent to a substrate. In some embodiments, the method comprises providing at least a first composition comprising a solid phase, wherein the solid phase comprises a reagent; and dispensing a first sample from the first composition onto a first coordinate on a substrate, whereby the first reagent is transferred to the substrate from the solid phase.

Abstract: Processes and systems for non-destructively storing, accessing, and editing information using nucleic acids are disclosed. Representative processes include a process for extracting a data file from a database, wherein the data file comprises information encoded into one or more polynucleotide strands and wherein the database comprises a plurality of polynucleotide strands; a process for expanding a number of unique data files in a database that can be addressed with a predetermined number of oligonucleotide primers, wherein the unique data files each comprise information encoded into one or more polynucleotide strands and wherein the database comprises a plurality of polynucleotide strands; a process for differentially reading information encoded into one or more polynucleotide strands; a process for manipulating files while in storage; and a process for extracting a data file from a database, wherein the data file comprises information encoded into a polynucleotide strand.

Abstract: A system and method for the design and operation of a cache system with differing cache location lengths in level one caches is disclosed. In one embodiment, each level one cache may include groups of cache locations of differing length, capable of holding portions of a level two cache line. A state tree may be created from data in a sharing vector. When a request arrives from a level one cache, the level two cache may examine the nodes of the state tree to determine whether the node of the state tree corresponding to the incoming request is already active. The results of this determination may be used to inhibit or permit the concurrent processing of the request.