Abstract: This disclosure relates to LINGO-1 polypeptides, LINGO-1 polypeptide/ligand complexes, crystals of LINGO-1 polypeptides, crystals of LINGO-1 polypeptide/ligand complexes, and related methods and software systems.

Abstract: This invention relates to progesterone receptor/ligand complex, and related methods and software systems. Methods for designing and/or selecting ligands of the progesterone receptor using the three-dimensional structural coordinates of the progesterone receptor and/or nonsteroidal ligands are disclosed.

Abstract: The present invention relates to the three dimensional solution structure of interleukin-13 (IL-13), as well as the identification and characterization of various binding active sites of IL-13. Also provided for by the present invention are methods of utilizing the three dimensional structure for the design and selection of potent and selective agents that interact with IL-13.

Abstract: An adverse terrain vehicle is provided which includes a system for controlling a number of vehicular functions. The vehicle includes at least two variable displacement hydraulic motors, each for driving at least one wheel member on one side of the vehicle independently of the wheel members on the opposing side thereof. At least two variable displacement hydraulic pumps are mounted on the vehicle for supplying pressurized hydraulic fluid to the hydraulic motor on one side of the vehicle independently of the hydraulic motor on the opposing side thereof. The hydraulic pumps are driven by an engine. A sensor detects a decrease in the power output of the vehicle below that selected by the vehicle operator. Overload protection circuitry is responsive to the overload sensor and adjusts the displacement of the hydraulic motors and pumps to increase the power output capacity of the vehicle. Braking control circuitry coordinates with braking of the vehicle steering to effect turning of the vehicle while braking.