Patents by Inventor James MacDonald Brewer

James MacDonald Brewer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Vaccines
    Patent number: 5876721
    Abstract: Vesicles comprising at least one non-ionic surfactant and at least one molecule having the ability to transport or facilitate the transport of fats, fatty acids and lipids across mucosal membranes. With entrapped antigen they can act as immunological adjuvants. Vaccines based therein are active orally as well as by conventional administration routes and are simulators of antibody production via the Th 1 T lymphocyte partway.
    Type: Grant
    Filed: May 8, 1996
    Date of Patent: March 2, 1999
    Assignees: Proteus Molecular Design Limited, The University of Strathclyde
    Inventors: James Alexander, James MacDonald Brewer
  • Vaccines containing non-ionic surfactant vesicles
    Patent number: 5679355
    Abstract: Non-ionic surfactant vesicles (NSIV) with entrapped antigen act as potent immunological adjuvants and can produce antibody titers of the same order of magnitude as those using Freund's Complete Adjuvant. The invention provides vaccines comprising such vesicles. Preferably non-ionic surfactants are glycerol esters particularly 1-monopalmitoyl glycerol. The vesicles may be administered by injection or via the mucosal route, oral administration being preferred.
    Type: Grant
    Filed: January 5, 1995
    Date of Patent: October 21, 1997
    Assignee: Proteus Molecular Design Limited
    Inventors: James Alexander, James MacDonald Brewer