Abstract: A stent includes a first wire and a second wire. The first wire is helically wound along an axis of a main body portion of the stent and along an axis of a first branch portion of the stent. The second wire is helically wound along the axis of the main body portion of the stent and along an axis of a second branch portion of the stent. The first wire and the second wire ar encapsulated in a graft member. A method for making a stent includes winding a first wire helically along a main body portion of a bifurcated mandrel and a first leg portion of the bifurcated mandrel. The method further includes winding a second wire helically along the main body portion of the bifircated mandrel and a second leg portion of the bifurcated mandrel. The first and second wires can be laminated within a graft material.

Abstract: A system for placement in at least one blood vessel includes a main graft body, one or more inflatable channels, and a filling structure. The one or more inflatable channels are attached to the main graft body. The filling structure is inflatable around at least a portion of the main graft body and at least a portion of at least one of the one or more inflatable channels. Various systems further include a graft extension that is insertable into a lumen formed by the main graft body, where the filling structure is inflatable around at least a portion of the graft extension. A method includes inserting a main graft body into a blood vessel, filling an inflatable channel attached to the main graft body, and filling a filling structure to inflate around at least a portion of the main graft body and at least a portion of the inflatable channel.

Abstract: A system for placement in at least one blood vessel includes a main graft body, one or more inflatable channels, and a filling structure. The one or more inflatable channels are attached to the main graft body. The filling structure is inflatable around at least a portion of the main graft body and at least a portion of at least one of the one or more inflatable channels. Various systems further include a graft extension that is insertable into a lumen formed by the main graft body, where the filling structure is inflatable around at least a portion of the graft extension. A method includes inserting a main graft body into a blood vessel, filling an inflatable channel attached to the main graft body, and filling a filling structure to inflate around at least a portion of the main graft body and at least a portion of the inflatable channel.

Abstract: A system includes a graft body and a filling structure. The graft body has a fenestration in a side surface through which a support structure is insertable. The filling structure has an internal volume that is tillable with a filling medium and is configured to have a conduit through the internal volume through which the support structure is insertable. The conduit in the filling structure is alignable with the fenestration in the graft body such that the support structure is insertable through both the conduit in the filling structure and the fenestration in the graft body.

Abstract: A stent graft includes at least one aperture extending through the main body thereof, into which an extension portion may be deployed for positioning within an adjacent branch flow lumen. The extension portions include self biasing features, wherein the extension is biased into engagement with the main body to seal the interface thereof. Additionally, the extension portion may be configured for tortuous or deviated anatomy, to enable sealing of the extension portion with the body while extending the extension portion in a substantially non-radial direction from the main body.

Abstract: Universal modular stented graft assemblies are assembled, on site, and often in a patient's parent artery, from at least two components; a first component and a second component. The first and second components each include a window, or fenestration. The second component couples with the first component by fitting at least partially in the first component to form the universal modular stent graft assembly with an adjustable collateral opening. As the first and second components are assembled, the first and second components are adjusted relative to each other so that the first and second component windows overlap to form a collateral opening whose size is selectable, depending on the overlap, with the desired position and dimensions in the universal modular stent graft assembly.

Abstract: A stent graft system and method of use includes a stent graft for fixation at an attachment site with graft material defining at least one opening having an opening perimeter; a support attached to the graft material; a guide rail attached around the opening perimeter; and a helical anchor having a plurality of coils with a point at one end. The plurality of coils are rotatable around the guide rail to cause the pointed end of the coils to penetrate the graft material and the adjacent tissue in contact with the stent graft to sew the stent graft to the attachment site.

Abstract: A method of securing a prosthesis placed at a desired site in a passageway of a human body comprises delivering a fastener having a proximal piercing end portion and a distal piercing end portion to a site where a prosthesis having a tubular wall has been placed in the passageway, which has a wall, advancing the proximal piercing end portion beyond the prosthesis, penetrating the proximal piercing end portion into the wall of the passageway without passing the proximal piercing end portion through the tubular wall of the prosthesis, and passing the distal piercing end portion through the tubular wall of the prosthesis and into the wall of the passageway. One surgical fastener delivery apparatus for delivering a surgical fastener to a target site comprises a support having a first end, a second end, and a longitudinal axis and being adapted for placement in a passageway in a human body.

Abstract: An aortic dissection treatment system and method of use including a treatment system for an aortic dissection having a catheter defining a suction lumen and a sealant lumen; a flexible cup defining an isolation region within the flexible cup, the isolation region being in communication with the suction lumen and the sealant lumen; and a sealant fluid deliverable to the aortic dissection through the sealant lumen and the isolation region. The flexible cup is sized to fit over at least one end of the aortic dissection and the suction lumen applies suction to maintain the flexible cup over the at least one end of the aortic dissection.

Abstract: A method and system for real-time continuous impedance monitoring along the surface of a graft implanted within a main vessel to aid in optimally positioning an electrode at a branch vessel ostium. Due to the conductivity differences among various kinds of solid tissue and blood, a fenestration catheter system uses impedance monitoring as a tool to detect the location of branch ostia through graft cloth. Such information enables the fenestration electrode to be properly positioned for creation of a fenestration in the graft cloth in situ. In addition, the fenestration catheter system may utilize impedance information to avoid contact between the electrode and metal stent structures used to anchor the graft during an in situ fenestration procedure. The fenestration catheter system includes a catheter shaft, an electrode, one or more reference or indifferent electrodes, an impedance analyzer, a power source and an electrode position reference to record impedance measurements in relation to position.

Abstract: A distal end of a stent graft fenestration or other special purpose catheter is guided to a location in a patient's vasculature based on input from a surgeon using a pre-operatively generated image of the patient's vasculature—this can be in proximity to an already implanted device. The movement of the catheter is controlled by a robotic surgical system based upon the input from the surgeon. The distal end of the catheter, at the location, is synchronized to the patient's cardiac cycle so the robotic surgical system maintains the distal end of the catheter at the location throughout a cardiac cycle of the patient. The surgeon is not required to precisely manipulate the catheter to maintain the distal end in the proper location throughout the cardiac cycle. The surgeon can focus on performing the desired procedure such as fenestrating the stent graft, endostapling or endosuturing, for example.

Abstract: A stent graft and method for positioning and deploying the stent graft within a vessel system that includes a main vessel and a branch vessel emanating from the main vessel. The stent graft includes a tubular shaped main body formed from graft material, a branch opening (aperture) (ring) in the graft material of the main body whose position can be varied. A tubular shaped branch graft can extend from the main graft. A side wall of the main body may be configured as a series of connected annular corrugations or pleats, and coupled to the main body to define and provide variable positioning of its branch opening (aperture).

Abstract: A stent graft and method for positioning and deploying the stent graft within a vessel system that includes a main vessel and a branch vessel emanating from the main vessel. The stent graft includes a tubular shaped main body formed from graft material, a branch opening (aperture)(ring) in the graft material of the main body whose position can be varied. A tubular shaped branch graft can extend from the main graft. A side wall of the main body may be configured as a series of connected annular corrugations or pleats, and coupled to the main body to define and provide variable positioning of its branch opening (aperture).

Abstract: A stent graft system and method of use includes a stent graft for fixation at an attachment site with graft material defining at least one opening having an opening perimeter; a support attached to the graft material; a guide rail attached around the opening perimeter; and a helical anchor having a plurality of coils with a point at one end. The plurality of coils are rotatable around the guide rail to cause the pointed end of the coils to penetrate the graft material and the adjacent tissue in contact with the stent graft to sew the stent graft to the attachment site.

Abstract: Universal modular stented graft assemblies are assembled, on site, and often in a patient's parent artery, from at least two components; a first component and a second component. The first and second components each include a window, or fenestration. The second component couples with the first component by fitting at least partially in the first component to form the universal modular stent graft assembly with an adjustable collateral opening. As the first and second components are assembled, the first and second components are adjusted relative to each other so that the first and second component windows overlap to form a collateral opening whose size is selectable, depending on the overlap, with the desired position and dimensions in the universal modular stent graft assembly.

Abstract: A stent graft includes at least one aperture extending through the main body thereof, into which an extension portion may be deployed for positioning within an adjacent branch flow lumen. The extension portions include self biasing features, wherein the extension is biased into engagement with the main body to seal the interface thereof. Additionally, the extension portion may be configured for tortuous or deviated anatomy, to enable sealing of the extension portion with the body while extending the extension portion in a substantially non-radial direction from the main body.

Abstract: Universal modular stented graft assemblies are assembled, on site, and often in a patient's parent artery, from at least two components; a first component and a second component. The first and second components each include a window, or fenestration. The second component couples with the first component by fitting at least partially in the first component to form the universal modular stent graft assembly with an adjustable collateral opening. As the first and second components are assembled, the first and second components are adjusted relative to each other so that the first and second component windows overlap to form a collateral opening whose size is selectable, depending on the overlap, with the desired position and dimensions in the universal modular stent graft assembly.

Abstract: A stent graft and method for positioning and deploying the stent graft within a vessel system that includes a main vessel and a branch vessel emanating from the main vessel. The stent graft includes a tubular shaped main body formed from graft material, a branch opening (aperture)(ring) in the graft material of the main body whose position can be varied. A tubular shaped branch graft can extend from the main graft. A side wall of the main body may be configured as a series of connected annular corrugations or pleats, and coupled to the main body to define and provide variable positioning of its branch opening (aperture).

Abstract: A method of using a delivery system includes advancing a stent to be located within an ostium of a vessel; advancing a basket actuation button of a handle to deploy a basket of the basket assembly; moving the basket into engagement with a parent vessel, the basket having a larger diameter than a diameter of the ostium; deploying the stent within an ostial lesion of the vessel; and contracting the basket.

Abstract: A method of securing a prosthesis placed at a desired site in a passageway of a human body comprises delivering a fastener having a proximal piercing end portion and a distal piercing end portion to a site where a prosthesis having a tubular wall has been placed in the passageway, which has a wall, advancing the proximal piercing end portion beyond the prosthesis, penetrating the proximal piercing end portion into the wall of the passageway without passing the proximal piercing end portion through the tubular wall of the prosthesis, and passing the distal piercing end portion through the tubular wall of the prosthesis and into the wall of the passageway. One surgical fastener delivery apparatus for delivering a surgical fastener to a target site comprises a support having a first end, a second end, and a longitudinal axis and being adapted for placement in a passageway in a human body.