Patents by Inventor James Madsen

James Madsen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250146926
    Abstract: An optical detection assembly for monitoring a biological fluid in a vessel includes two fluid-adjustment structures, which are spaced apart and configured to receive at least a portion of a biological fluid-containing vessel therebetween. A light source (which may be associated with one of the fluid-adjustment structures) is configured to emit light through a thickness of the biological fluid in the vessel, while a light detector (which may be associated with the other one of the fluid-adjustment structures) is configured to receive at least a portion of the light from the light source after it has passed through the biological fluid in the vessel. At least a portion of at least one of the fluid-adjustment structures is configured to move with respect to at least a portion of the other one so as to change the thickness of the biological fluid in the monitored portion of the vessel.
    Type: Application
    Filed: January 13, 2025
    Publication date: May 8, 2025
    Inventors: Benjamin E. Kusters, Daniel R. Boggs, James Madsen, Jeannette Wu, Matthew Fang
  • Patent number: 12290624
    Abstract: An irradiation device includes a processing container including a first chamber, a second chamber and at least one narrow passage in fluid communication at a first end with the first chamber and at a second end with the second chamber, and a rotatable table on which the processing container is mounted, the table having a first state wherein the first chamber is disposed at a higher elevation than the second chamber, and a second state wherein the second chamber is disposed at a higher elevation than the first chamber. The irradiation device also includes ultraviolet (UV) light source disposed proximate to the narrow passage and configured to irradiate fluid passing through the narrow passage.
    Type: Grant
    Filed: July 31, 2020
    Date of Patent: May 6, 2025
    Assignee: Fenwal, Inc.
    Inventor: James Madsen
  • Publication number: 20250137833
    Abstract: A system for splitting a fluid includes a source support configured to support a source container of a fluid flow circuit and at least one satellite support, with each satellite support configured to support a different satellite container fluidly connected to the source container. A weight scale is associated with each of the supports. The system also includes a clamp system and a controller. The controller is configured to control each weight scale to measure a combined weight of the container and the contents of the container supported by the support associated with the weight scale. The controller is configured to control the clamp system to selectively allow and prevent fluid flow from the source container to each satellite container based at least in part upon the weights measured by each weight scale. Fluid flow continues until the contents of each container have reached a target volume.
    Type: Application
    Filed: January 2, 2025
    Publication date: May 1, 2025
    Inventors: James Madsen, Kyungyoon Min
  • Patent number: 12285758
    Abstract: A lab-on-a-chip cartridge includes a housing defining four separate chambers. A fluid (such as whole blood) flows through one of the chambers and into another one of the chambers, which includes a filter membrane. The filter membrane is rotated to separate a first fluid component (such as plasma) from a second fluid component (such as red blood cells), with the first fluid component passing through the filter membrane and the second fluid component not passing through the filter membrane. The separated first and second fluid components each flow into a different one of the remaining chambers, with the first fluid component contacting a lab-on-a-chip device for analyzing the first fluid component.
    Type: Grant
    Filed: October 13, 2021
    Date of Patent: April 29, 2025
    Assignee: Fenwal, Inc.
    Inventor: James Madsen
  • Patent number: 12280231
    Abstract: Sterile connection systems and methods are disclosed. The systems and methods allow for connection of the facing ends of plastic tubing defining flow paths without welding or tube cutting. The two ends may be disconnected, re-sterilized and subsequently reused to make a new sterile connection.
    Type: Grant
    Filed: April 1, 2021
    Date of Patent: April 22, 2025
    Assignee: Fenwal, Inc.
    Inventor: James Madsen
  • Patent number: 12235208
    Abstract: An optical detection assembly for monitoring a biological fluid in a vessel includes two fluid-adjustment structures, which are spaced apart and configured to receive at least a portion of a biological fluid-containing vessel therebetween. A light source (which may be associated with one of the fluid-adjustment structures) is configured to emit light through a thickness of the biological fluid in the vessel, while a light detector (which may be associated with the other one of the fluid-adjustment structures) is configured to receive at least a portion of the light from the light source after it has passed through the biological fluid in the vessel. At least a portion of at least one of the fluid-adjustment structures is configured to move with respect to at least a portion of the other one so as to change the thickness of the biological fluid in the monitored portion of the vessel.
    Type: Grant
    Filed: April 13, 2022
    Date of Patent: February 25, 2025
    Assignee: Fenwal, Inc.
    Inventors: Benjamin E. Kusters, Daniel R. Boggs, James Madsen, Jeannette Wu, Matthew Fang
  • Patent number: 12233412
    Abstract: Disclosed are cartridge components, cartridges, systems, and methods for isolating analytes from biological samples. In various aspects, the cartridge components, cartridges, systems, and methods may allow for a rapid procedure that requires a minimal amount of material from complex fluids.
    Type: Grant
    Filed: December 15, 2022
    Date of Patent: February 25, 2025
    Assignee: Xzom, Inc.
    Inventors: Robert Turner, James Madsen, Kai Yang, Juan Pablo Hinestrosa Salazar, Rajaram Krishnan, Pedro David Simon Herrera
  • Patent number: 12222235
    Abstract: A system for splitting a fluid includes a source support configured to support a source container of a fluid flow circuit and at least one satellite support, with each satellite support configured to support a different satellite container fluidly connected to the source container. A weight scale is associated with each of the supports. The system also includes a clamp system and a controller. The controller is configured to control each weight scale to measure a combined weight of the container and the contents of the container supported by the support associated with the weight scale. The controller is configured to control the clamp system to selectively allow and prevent fluid flow from the source container to each satellite container based at least in part upon the weights measured by each weight scale. Fluid flow continues until the contents of each container have reached a target volume.
    Type: Grant
    Filed: July 16, 2020
    Date of Patent: February 11, 2025
    Assignee: Fenwal, Inc.
    Inventors: James Madsen, Kyungyoon Min
  • Patent number: 12161784
    Abstract: Methods and systems for transfusing reduced-volume blood components are disclosed. Previously collected blood components are introduced into a fluid circuit associated with an apparatus that further separates the component into a reduced volume component and supernatant. The reduced-volume blood component is transfused to the patient in need of the component without the risk of circulatory overload.
    Type: Grant
    Filed: October 3, 2022
    Date of Patent: December 10, 2024
    Assignee: Fenwal, Inc.
    Inventors: Kyungyoon Min, James Madsen, Thomas Gniadek
  • Patent number: 12011530
    Abstract: A plasmapheresis system and a method for operating a plasmapheresis system are provided by which the reservoir for the concentrated red blood cells (RCC) has a first chamber for receiving anticoagulant used for priming the separator and purging the system of air prior to the initial draw cycle and a second chamber for receiving separated red blood cells. Because the entire volume of second chamber of the RCC reservoir may now receive separated red blood cells and no AC prime volume, a greater amount of whole blood may be processed in the first draw cycle, thus resulting in a greater total volume of Immunoglobulin G (IgG) being collected during the plasmapheresis procedure.
    Type: Grant
    Filed: June 21, 2021
    Date of Patent: June 18, 2024
    Assignee: Fenwal, Inc.
    Inventor: James Madsen
  • Publication number: 20240165308
    Abstract: A method and system for drawing and collecting blood and/or blood components is disclosed. The method and system include a patient temperature monitoring device for monitoring a patient's temperature throughout a collection procedure, which includes an infrared camera. The infrared camera may be calibrated regularly to ensure accurate measurements.
    Type: Application
    Filed: November 16, 2023
    Publication date: May 23, 2024
    Inventors: James Madsen, Winston Ding
  • Publication number: 20240157035
    Abstract: A system and method for splitting a fluid into fluid products with a component count within a designated component count range and volume within a designated volume range. The method includes measuring an initial component concentration of a source container, weighing a source container to determine the volume of fluid, calculating the final component count and final volume for each of the source and at least one satellite container, calculating the amount of component additive solution to add the source container and flowing the amount of component additive solution from a component additive solution container into the source container, and splitting the fluid so that each divided fluid amount has a final component count within a designated component count range and a final volume within a designated volume range.
    Type: Application
    Filed: November 7, 2023
    Publication date: May 16, 2024
    Inventors: James Madsen, Kyungyoon Min
  • Publication number: 20230285613
    Abstract: A device, system, and method for sterilizing a fluid pathway connection are disclosed. The device, system, and method utilize a hand-held sterilization device. The device may create temporary sterile flow paths.
    Type: Application
    Filed: March 10, 2023
    Publication date: September 14, 2023
    Inventors: James Madsen, Christopher J. Wegener
  • Publication number: 20230285734
    Abstract: Systems, devices and methods for establishing a sterile fluid flow path between two or more fluid processing sets are disclosed. The systems, devices and methods include two or more connectors to which tubes of two or more fluid processing sets are attached. The connectors are brought together in an air-tight, non-permanent engagement with one another and treated with sterilizing light.
    Type: Application
    Filed: March 10, 2023
    Publication date: September 14, 2023
    Inventors: James Madsen, Christopher J. Wegener
  • Patent number: 11731371
    Abstract: A sterile connection device includes first and second carriages. The first carriage defines a first portion of a proximal slot and a first portion of a distal slot, while the second carriage defines second portions of the proximal and distal slots. A controller executes a sterile connection procedure in which a solid cutting blade is heated, followed by the heated blade being moved to a cutting position to cut sealed proximal and distal tubes received by the slots. The second carriage moves proximally or distally with respect to the first carriage so as to align the cut ends of the tubes. The heated blade then moves out of the cutting position, followed by the first carriage moving toward the second carriage so as to press the cut ends of the tubes into contact with each other so as to sterilely connect the cut ends and define a joined tube.
    Type: Grant
    Filed: January 21, 2022
    Date of Patent: August 22, 2023
    Assignee: Fenwal, Inc.
    Inventors: James Madsen, Kyungyoon Min, Mark J. Brierton, Tom Westberg
  • Publication number: 20230253189
    Abstract: In some examples, a double seal arrangement for a substrate processing chamber comprises a radially inner barrier seal disposed within a barrier seal gland. The barrier seal gland includes an inner toe and an outer toe. A radially outer vacuum seal is disposed within a vacuum seal gland. The vacuum seal gland includes at least an inner toe. A first venting pathway is provided between the inner toe of the vacuum seal gland and the outer toe of the barrier seal gland, and a second venting pathway is provided between the outer toe of the barrier seal gland and the inner toe of the barrier seal gland. A third venting pathway is in communication at least with the inner toe of the barrier seal gland, and a vacuum source connected to at least one of the first, second, and third venting pathways.
    Type: Application
    Filed: June 30, 2021
    Publication date: August 10, 2023
    Inventors: Hui Ling Han, Michael Julius Kinsler, Steven James Madsen, Gabriel Pioux
  • Publication number: 20230182132
    Abstract: Disclosed are cartridge components, cartridges, systems, and methods for isolating analytes from biological samples. In various aspects, the cartridge components, cartridges, systems, and methods may allow for a rapid procedure that requires a minimal amount of material from complex fluids.
    Type: Application
    Filed: December 15, 2022
    Publication date: June 15, 2023
    Inventors: Robert TURNER, James MADSEN, Kai YANG, Juan Pablo HINESTROSA SALAZAR, Rajaram KRISHNAN, Pedro David SIMON HERRERA
  • Publication number: 20230108077
    Abstract: Methods and systems for transfusing reduced-volume blood components are disclosed. Previously collected blood components are introduced into a fluid circuit associated with an apparatus that further separates the component into a reduced volume component and supernatant. The reduced-volume blood component is transfused to the patient in need of the component without the risk of circulatory overload.
    Type: Application
    Filed: October 3, 2022
    Publication date: April 6, 2023
    Inventors: Kyungyoon Min, James Madsen, Thomas Gniadek
  • Publication number: 20230084959
    Abstract: A blood pack donation system configured for use with a lab-on-a-chip device for biomarker collection during whole blood donation including a blood collection container, a biomarker collection container, a first flow path connected to an opening in the blood collection container and to a first outlet opening of a lab-on-a-chip device, a second flow path connected to an opening in the biomarker collection container and to a second outlet opening of the lab-on-a-chip device, and a third flow path connected to a needle and to an inlet opening of the lab-on-a-chip device. The system may be used in a single pass collection procedure. A second version includes a fourth flow path connected to the first flow path and to the third flow path, with a plurality of flow control components that selectively control flow to provide a single pass collection procedure or a multiple pass collection procedure.
    Type: Application
    Filed: August 29, 2022
    Publication date: March 16, 2023
    Inventor: James Madsen
  • Publication number: 20230082317
    Abstract: A magnetic selector includes a housing configured to receive a container and having a floor upon which the container is disposed. The selector also includes a magnet carrier disposed on an opposite side of the floor from the container. The magnet carrier has at least one magnet disposed thereon and being moveable relative to the floor between a first state wherein the magnet carrier is adjacent the floor and a second state wherein the magnet carrier is spaced from the floor. The selector may include a door. The magnetic selector is usable in a fluid processing system that includes a fluid processor connectable to a source container filled with a biological fluid. A container is disposed in the magnetic selector and connected to the processor along a fluid pathway. The processor is configured to separate the biological fluid from the source container into at least two streams of material.
    Type: Application
    Filed: September 6, 2022
    Publication date: March 16, 2023
    Inventors: Christopher J. Wegener, James Madsen