Abstract: Securement arrangements for use in securing a patient interface to the skin of a patient include a substrate material having a first surface and an adhesive material disposed on the first surface. The locations of the adhesive material are varied so as to minimize repetitious adherence of the adhesive material to the patient during repeated applications.

Abstract: The present invention relates to RNAi agents, e.g., double stranded RNAi agents, targeting the Kallikrein B, Plasma (Fletcher Factor) 1 (KLKB1) gene, the Factor XII (Hageman Factor (F12) gene, or the Kininogen 1 (KNG1) gene, and methods of using such RNAi agents to inhibit expression of a KLKB1 gene, an F12 gene, and/or a KNG1 gene, and methods of treating subjects having an hereditary angioedema (HAE) and/or a contact activation pathway-associated disorder.

Abstract: A method and System for identifying chemical compounds based on Raman spectroscopic measurements and in-silico simulated Raman spectra are disclosed. In various embodiments, Raman barcodes of an unknown chemical compound may be generated from Raman spectra obtained by performing Raman spectroscopic measurements on the unknown chemical compound. The Raman barcodes may then be compared with a library of reference in-silico simulated Raman barcodes of known chemical compounds and the identity of the unknown chemical compound may be determined based on the comparison.

Abstract: A patient interface for use in delivering a flow of breathing gas to an airway of a patient. The patient interface includes a front portion and a rear portion coupled to the front portion. The front portion and the rear portion together define a cavity therebetween which is structured to receive the flow of breathing gas. The rear portion includes a support layer disposed directly adjacent the cavity, the support layer having a region having a plurality of first thru-holes structured to receive the flow of breathing gas from the cavity. The rear portion further includes a patient engaging layer structured to engage the patient at or about the airway of the patient, the patient engaging layer including at least a second thru-hole structured to receive the flow of breathing gas from the plurality of first thru-holes.

Abstract: An improved scraping edge for use on a plow blade employing at least one resilient scraping edge section for contact with a surface to be plowed and mounting holes to attach the scraping edge section to the plow blade.

Abstract: An improved material pusher or containment plow employing a floating vehicle-coupling system, a wear shoe, as well as a plurality of removable scraping edge sections.

Abstract: Techniques are disclosed for using a genetic algorithm to identify a processing pipeline that transforms spectra into a form usable to generate predicted characteristics of corresponding samples. The genetic algorithm is used to generate and evaluate multiple candidate solutions specifying various pre-processing and machine-learning-processing configurations. The processing pipeline is defined based on the candidate solutions.

Abstract: Securement arrangements for use in securing a patient interface to the skin of a patient include a substrate material having a first surface and an adhesive material disposed on the first surface. The locations of the adhesive material are varied so as to minimize repetitious adherence of the adhesive material to the patient during repeated applications.

Abstract: An improved material pusher or containment plow employing a floating vehicle-coupling system, a modular composite scraping edge, a front-pivoting wear shoe with an adjustable angle, as well as water-shedding features. The disclosed containment plow and features are provide improved the surface outcome under various snow and ice conditions.

Abstract: An improved material pusher or containment plow employing a floating vehicle coupling system, a modular composite scraping edge, a front-pivoting wear shoe with an adjustable angle, as well as water-shedding features. The disclosed containment plow and features provide improved the surface outcomes under various snow and ice conditions.

Abstract: An improved material pusher or containment plow employing a floating vehicle-coupling system, a modular composite scraping edge, a front-pivoting wear shoe with an adjustable angle, as well as water-shedding features. The disclosed containment plow and features are provide improved the surface outcome under various snow and ice conditions.

Abstract: An improved material pusher or containment plow employing a floating vehicle-coupling system, a modular composite scraping edge, a front-pivoting wear shoe with an adjustable angle, as well as water-shedding features. The disclosed containment plow and features are provide improved the surface outcome under various snow and ice conditions.

Abstract: An improved material pusher or containment plow employing a floating vehicle-coupling system, a modular composite scraping edge, a front-pivoting wear shoe with an adjustable angle, as well as water-shedding features.

Abstract: A patient interface for use in delivering a flow of breathing gas to an airway of a patient. The patient interface includes a front portion and a rear portion coupled to the front portion. The front portion and the rear portion together define a cavity therebetween which is structured to receive the flow of breathing gas. The rear portion includes a support layer disposed directly adjacent the cavity, the support layer having a region having a plurality of first thru-holes structured to receive the flow of breathing gas from the cavity. The rear portion further includes a patient engaging layer structured to engage the patient at or about the airway of the patient, the patient engaging layer including at least a second thru-hole structured to receive the flow of breathing gas from the plurality of first thru-holes.

Abstract: A pivot coupling system that permits the use of attachable equipment such as material pushers or containment plows with a range of vehicles including all-terrain vehicles (ATVs), utility task vehicle (UTV), lawn and garden tractors, small farm tractors, small trucks, skid-steer loaders, etc.

Abstract: An improved material pusher or containment plow employing a floating vehicle-coupling system, a modular composite scraping edge, a front-pivoting wear shoe with an adjustable angle, as well as water-shedding features. The disclosed containment plow and features are provide improved the surface outcome under various snow and ice conditions.

Abstract: An improved material pusher or containment plow employing a floating vehicle-coupling system, a modular composite scraping edge, a front-pivoting wear shoe with an adjustable angle, as well as water-shedding features. The disclosed containment plow and features are provide improved the surface outcome under various snow and ice conditions.

Abstract: An improved material pusher or containment plow employing a floating vehicle-coupling system, a modular composite scraping edge, a front-pivoting wear shoe with an adjustable angle, as well as water-shedding features. The disclosed containment plow and features are provide improved the surface outcome under various snow and ice conditions.

Abstract: A technique for incrementally unloading classes using a region-based garbage collector is described. One aspect of such a technique includes maintaining a remembered set for a class set. The remembered set indicates whether instances of the class set are contained in one or more regions in memory, and in which regions the instances are contained. Upon performing an incremental garbage collection process for a subset of the regions in memory, the technique examines the remembered set to determine whether the class set includes instances in regions outside of the subset. If the remembered set indicates that the class set includes instances outside of the subset of regions, the technique identifies the class set as “live.” This will preclude unloading the class set from the subset of regions.

Abstract: A pivot coupling system that permits the use of attachable equipment such as material pushers or containment plows with a range of vehicles including all-terrain vehicles (ATVs), utility task vehicle (UTV), lawn and garden tractors, small farm tractors, small trucks, skid-steer loaders, etc.