Patents by Inventor James Mainquist

James Mainquist has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20070105214
    Abstract: High throughput and automated cellular disruption systems that substantially uniformly disrupt cells as part of cellular motility assays as wells as other assay types are provided. In addition, various system components, including holding blocks, holding block loading devices, and system software, are also provided. Moreover, related methods that utilize these systems and system components are additionally provided.
    Type: Application
    Filed: November 9, 2005
    Publication date: May 10, 2007
    Applicants: IRM, LLC, THE SCRIPPS RESEARCH INSTITUTE
    Inventors: Kenneth Micklash, Jiyong Hong, James Mainquist, Sheng Ding, Robert Downs, Peter Schultz
  • Publication number: 20070031963
    Abstract: Cell culture flasks that are readily conducive to various automated processing applications, including introducing and removing fluid from the flasks are provided. Automated cell culture flask processing systems, system components, and related methods are also provided.
    Type: Application
    Filed: May 31, 2006
    Publication date: February 8, 2007
    Inventors: Jim Chang, James Mainquist, Robert Downs, Randal Wayne, Daniel Sipes
  • Publication number: 20070005182
    Abstract: The present invention provides grasping mechanisms, gripper apparatus/systems, and related methods. Grasping mechanisms that include stops, support surfaces, and height adjusting surfaces to determine three translational axis positions of a grasped object are provided. In addition, grasping mechanisms that are resiliently coupled to other gripper apparatus components are also provided.
    Type: Application
    Filed: September 6, 2006
    Publication date: January 4, 2007
    Inventors: Robert Downs, Mark Weselak, James Mainquist
  • Publication number: 20060257999
    Abstract: High throughput compound profiling systems, and related devices and sub-systems that can be used to perform various compound profiling processes are provided. These systems typically include work perimeters that are organized for optimum efficiency and processing accuracy. Further, these systems are readily adaptable for performing a wide array of assays, as many different system components are easily incorporated or interchangeable in a particular system. System components that are provided by the invention include cell culture dissociators, which can be used, e.g., to effect cell wetting, dissociation, and/or agitation applications. In some embodiments, these cell culture dissociators are included as components of automated cell culture passaging stations. Dispensing devices that permit on-the-fly fluid temperature regulation are also provided. In addition, various compound profiling methods, cell dissociation methods, uniform cell concentration dispensing methods, among other processes, are also provided.
    Type: Application
    Filed: March 22, 2006
    Publication date: November 16, 2006
    Inventors: Jim Chang, James Mainquist, Robert Downs, Jeremy Caldwell, Frederick King
  • Publication number: 20060188409
    Abstract: The present invention provides multi-well container positioning devices and systems. In certain embodiments, these devices and systems are structured to compensate for structural defects or irregularities of multi-well containers so that the containers are accurately positioned for further processing. In some embodiments, multi-well container positioning devices and systems include multiple chambers that can be used to retain multi-well containers in selected positions on the positioning devices in a desired sequence. In addition, related computer program products and methods are also provided.
    Type: Application
    Filed: January 18, 2006
    Publication date: August 24, 2006
    Applicant: IRM LLC
    Inventors: Jim Chang, James Mainquist
  • Publication number: 20060051247
    Abstract: The present invention provides fluid removal heads and related multi-well container processing systems for the efficient removal of fluids from multi-well containers. Methods of removing fluid from multi-well containers are also provided.
    Type: Application
    Filed: August 3, 2005
    Publication date: March 9, 2006
    Applicant: IRM, LLC
    Inventors: Kenneth Micklash, Robert Downs, Jim Chang, James Mainquist
  • Publication number: 20060002824
    Abstract: The present invention provides dispensing systems that include peristaltic pumps and other pressure sources for the efficient delivery of accurate volumes of fluidic materials into the wells of multi-well containers or onto substrate surfaces. These systems are typically configured to dispense volumes of fluid having substantially uniform densities. Related computer program products and methods of dispensing fluidic materials are also provided.
    Type: Application
    Filed: June 6, 2005
    Publication date: January 5, 2006
    Applicant: IRM, LLC
    Inventors: Jim Chang, Kenneth Micklash, Robert Downs, James Mainquist, Christopher Shaw
  • Publication number: 20050277199
    Abstract: The present invention relates to high-throughput compound purification and analysis systems that include representative sample fraction storage components that are structured to at least transiently store representative sample fraction aliquots prior to analysis. In addition, related computer program products and methods are also provided.
    Type: Application
    Filed: May 24, 2005
    Publication date: December 15, 2005
    Applicant: IRM LLC
    Inventors: John Isbell, Matthew Rynd, Tessa Rynd, Ding Yuan, James Mainquist, Andrew Meyer
  • Publication number: 20050232743
    Abstract: The present invention provides grasping mechanisms, gripper apparatus/systems, and related methods. Grasping mechanisms that include stops, support surfaces, and height adjusting surfaces to determine three translational axis positions of a grasped object are provided. In addition, grasping mechanisms that are resiliently coupled to other gripper apparatus components are also provided.
    Type: Application
    Filed: June 21, 2005
    Publication date: October 20, 2005
    Applicant: IRM LLC
    Inventors: Robert Downs, Mark Weselak, James Mainquist
  • Publication number: 20050163637
    Abstract: This invention provides material conveying systems that are configured to convey substantially uniform quantities of material to and/or from the material sites and to minimize periodic variation among the conveyed quantities of material. Related computer program products and methods are also provided.
    Type: Application
    Filed: December 1, 2004
    Publication date: July 28, 2005
    Applicant: IRM, LLC
    Inventors: Jim Chang, James Mainquist, Robert Downs, Chris Petersen, Daniel Sipes
  • Publication number: 20050058577
    Abstract: The present invention provides material removal heads and devices for noninvasively removing materials from the wells of multi-well plates. The material removal heads of the invention are structured to prevent cross-contamination among wells of multi-well plates as materials are removed from the plates. The invention also provides dispense heads and devices that include angled dispensers. Related systems, kits, and methods are additionally provided.
    Type: Application
    Filed: April 7, 2004
    Publication date: March 17, 2005
    Applicant: IRM, LLC
    Inventors: Kenneth Micklash, Robert Downs, Jim Chang, James Mainquist