Patents by Inventor James Malcolm MacLean

James Malcolm MacLean has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Expression of proteins in plants
    Patent number: 9017987
    Abstract: The invention relates to a method of producing an influenza virus H5 polypeptide in a plant comprising the steps of cloning an influenza H5 gene or nucleic acid encoding its functional equivalent into a vector adapted to target components present in the plant, infiltrating at least a portion of the plant with the vector or transforming plant tissue with the vector so as to transiently express the influenza virus H5 polypeptide, and/or to create a transgenic plant; and recover the influenza virus H5 polypeptide expressed by the plant. The invention further relates to vectors, transgenic plants or parts thereof and the progeny of such plants used in or which come about as a result of the method.
    Type: Grant
    Filed: January 29, 2013
    Date of Patent: April 28, 2015
    Assignee: University of Cape Town
    Inventors: Anna-Lise Williamson, Edward Peter Rybicki, James Malcolm Maclean, Inga Isabel Becker-Hitzeroth
  • Expression of proteins in plants
    Patent number: 8535930
    Abstract: The invention relates to a method of producing a HPV polypeptides and/or an influenza virus H5 polypeptide in a plant comprising the steps of cloning a HPV gene; and/or an influenza virus H5 gene or nucleic acid encoding their functional equivalents into a vector adapted to target components present in the plant, infiltrating at least a portion of the plant with the vector or transforming plant tissue with the vector so as to transiently express the HPV polypeptides and/or an influenza virus H5 polypeptide, and/or to create a transgenic plant; and recovering the HPV polypeptides and/or an influenza virus H5 polypeptide expressed by the plant. The invention further relates to vectors, transgenic plants or parts thereof and the progeny of such plants used in or which come about as a result of the method.
    Type: Grant
    Filed: May 2, 2006
    Date of Patent: September 17, 2013
    Assignee: University of Cape Town
    Inventors: Anna-Lise Williamson, Edward Peter Rybicki, James Malcolm MacLean, Inga Isabel Becker-Hitzeroth
  • Expression of Proteins in Plants
    Publication number: 20090220543
    Abstract: The invention relates to a method of producing a HPV polypeptides and/or an influenza virus H5 polypeptide in a plant comprising the steps of cloning a HPV gene; and/or an influenza virus H5 gene or nucleic acid encoding their functional equivalents into a vector adapted to target components present in the plant, infiltrating at least a portion of the plant with the vector or transforming plant tissue with the vector so as to transiently express the HPV polypeptides and/or an influenza virus H5 polypeptide, and/or to create a transgenic plant; and recovering the HPV polypeptides and/or an influenza virus H5 polypeptide expressed by the plant. The invention further relates to vectors, transgenic plants or parts thereof and the progeny of such plants used in or which come about as a result of the method.
    Type: Application
    Filed: May 2, 2006
    Publication date: September 3, 2009
    Inventors: Anna-Lise Williamson, Edward Peter Rybicki, James Malcolm MacLean, Inga Isabel Becker-Hitzeroth