Patents by Inventor James Martin Lenhard

James Martin Lenhard has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Combinations of dipeptidyl peptidase IV inhibitors and other antidiabetic agents for the treatment of diabetes mellitus
    Patent number: 7241756
    Abstract: A method for the treatment of diabetes mellitus, especially Type 2 diabetes and conditions associated with diabetes mellitus in a mammal such as a human, which method comprises administering an effective, non-toxic and pharmaceutically acceptable amount of a dipeptidyl peptidase IV inhibitor and another antidiabetic agent, to a mammal in need thereof.
    Type: Grant
    Filed: June 1, 2006
    Date of Patent: July 10, 2007
    Assignee: SmithKline Beecham Corporation
    Inventors: Jonathan Robert Sanders Arch, James Martin Lenhard
  • Fluoropyrrolidines as dipeptidyl peptidase inhibitors
    Patent number: 7183290
    Abstract: The present invention relates to novel compounds, their use for inhibiting post prolin/analine-cleaving proteases, such as serine proteases, such as dipeptidyl peptidases, such as dipeptidyl peptidase IV (DPP-IV), and to methods for their production and their therapeutic utility.
    Type: Grant
    Filed: June 26, 2002
    Date of Patent: February 27, 2007
    Assignee: SmithKline Beecham Corporation
    Inventors: Curt Dale Haffner, Darryl Lynn McDougald, James Martin Lenhard
  • Fluoropyrrolidines as dipeptidyl peptidase inhibitors
    Patent number: 7132443
    Abstract: The present invention relates to novel compounds, their use for inhibiting serine proteases, such as dipeptidyl peptidases, such as dipeptidyl peptidase IV (DPP-IV) and to methods for their production and their therapeutic utility.
    Type: Grant
    Filed: June 26, 2002
    Date of Patent: November 7, 2006
    Assignee: SmithKlineBeecham Corporation
    Inventors: Curt Dale Haffner, Darryl Lynn McDougald, Amarjit Sab Randhawa, Steven Michael Reister, James Martin Lenhard
  • Combinations of dipeptidyl peptidase IV inhibitors and other antidiabetic agents for the treatment of diabetes mellitus
    Patent number: 7078397
    Abstract: Disclosed is a method for the treatment of diabetes mellitus, especially Type 2 diabetes and conditions associated with diabetes mellitus in a mammal such as a human, which method comprises administering an effective, non-toxic and pharmaceutically acceptable amount of a dipeptidyl peptidase IV inhibitor and another antidiabetic agent, to a mammal in need thereof.
    Type: Grant
    Filed: June 19, 2001
    Date of Patent: July 18, 2006
    Assignee: SmithKline Beecham Corporation
    Inventors: Jonathan Robert Sanders Arch, James Martin Lenhard
  • Infrared thermography
    Patent number: 6983753
    Abstract: The present invention relates, in general, to thermography and, in particular, to a method of using infrared thermography to monitor physiological and molecular events that elicit a thermogenic response in animals (including humans), plants, tissues, cells and cell-free systems. The present method can be used for screening, identifying, and ranking drug candidates for multiple diseases, disorders and conditions.
    Type: Grant
    Filed: November 17, 2000
    Date of Patent: January 10, 2006
    Assignee: SmithKline Beecham Corporation
    Inventors: James Martin Lenhard, Mark Andrew Paulik
  • Infrared thermography
    Patent number: 6881584
    Abstract: The present invention relates, in general, to thermography and, in particular, to a method of using infrared thermography to monitor physiological and molecular events that elicit a thermogenic response in animals (including humans), plants, tissues, cells and cell-free systems. The present method can be used for screening, identifying, and ranking drug candidates for multiple diseases, disorders and conditions.
    Type: Grant
    Filed: November 17, 1999
    Date of Patent: April 19, 2005
    Assignee: SmithKline Beecham Corporation
    Inventors: James Martin Lenhard, Mark Andrew Paulik
  • Fluoropyrrolidines as dipeptidyl peptidase inhibitors
    Publication number: 20040242636
    Abstract: The present invention relates to novel compounds, their use for inhibiting post prolin/analine-cleaving proteases, such as serine proteases, such as dipeptidyl peptidases, such as dipeptidyl peptidase IV (DPP-IV), and to methods for their production and their therapeutic utility.
    Type: Application
    Filed: December 19, 2003
    Publication date: December 2, 2004
    Inventors: Curt Dale Haffner, Darryl Lynn McDougald, James Martin Lenhard
  • Fluoropyrrolidines as dipeptidyl peptidase inhibitors
    Publication number: 20040171848
    Abstract: The present invention relates to novel compounds, their use for inhibiting serine proteases, such as dipeptidyl peptidases, such as dipeptidyl peptidase IV (DPP-IV) and to methods for their production and their therapeutic utility.
    Type: Application
    Filed: December 19, 2003
    Publication date: September 2, 2004
    Inventors: Curt Dale Haffner, Darryl Lynn McDougald, Amarjit Sab Randhawa, Steven Michael Reister, James Martin Lenhard
  • COMBINATIONS OD DIPEPTIDYL PEPTIDASE IV INHIBITORS AND OTHER ANTIDIABETIC AGENTS FOR THE TREATMENT OF DIABETES MELLITUS
    Publication number: 20030166578
    Abstract: A method for the treatment of diabetes mellitus, especially Type 2 diabetes and conditions associated with diabetes mellitus in a mammal such as a human, which method comprises administering an effective, non-toxic and pharmaceutically acceptable amount of a dipeptidyl peptidase IV inhibitor and another antidiabetic agent, to a mammal in need thereof.
    Type: Application
    Filed: February 20, 2003
    Publication date: September 4, 2003
    Inventors: Jonathan Robert Sanders Arch, James Martin Lenhard
  • Thiazole derivatives as PPAR gamma ligands
    Patent number: 6541492
    Abstract: The present invention discloses novel PPAR gamma ligands of Formula (I) and pharmaceutically acceptable salts and solvates thereof. The present invention also discloses a method for treating osteoporosis by administration of a PPAR gamma antagonist.
    Type: Grant
    Filed: May 11, 2001
    Date of Patent: April 1, 2003
    Assignee: SmithKline Beecham Corporation
    Inventors: Jon Loren Collins, Christopher Patrick Holmes, James Martin Lenhard, Timothy Mark Willson
  • PPAR gamma ligands
    Publication number: 20020151569
    Abstract: The present invention discloses a method for treating osteoporosis by administration of a PPAR gamma antagonist.
    Type: Application
    Filed: April 3, 2002
    Publication date: October 17, 2002
    Inventors: Jon Loren Collins, Christopher Patrick Holmes, James Martin Lenhard, Timothy Mark Willson