Patents by Inventor James Martin NOLAN III

James Martin NOLAN III has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • POLYMORPHIC COMPOUNDS AND USES THEREOF
    Publication number: 20230286990
    Abstract: The present invention provides freebase and salt forms, and compositions and methods thereof, useful for treating various conditions in which the aryl hydrocarbon receptor (AHR) is implicated, by the administration of small molecule therapeutics which act as inhibitors of AHR.
    Type: Application
    Filed: January 19, 2023
    Publication date: September 14, 2023
    Inventors: Alfredo C. Castro, James Martin Nolan, III, Sarah Jean Bethune, Corinne Marie Folberth
  • Solid forms of (R)-N-(2-(5-fluoropyridin-3-yl)-8-isopropylpyrazolo[ 1,5-a][1,3,5]triazin-4-yl)-2,3,4,9-tetrahydro-1H-carbazol-3-amine maleate as aryl hydrocarbon receptor (AHR) inhibitors
    Patent number: 11591339
    Abstract: The present invention provides solid forms of (R)—N-(2-(5-fluoropyridin-3-yl)-8-isopropylpyrazolo[1,5-a][1,3,5]triazin-4-yl)-2,3,4,9-tetrahydro-1H-carbazol-3-amine maleate (Compound 2) represented by the formula:
    Type: Grant
    Filed: November 25, 2020
    Date of Patent: February 28, 2023
    Assignee: IKENA ONCOLOGY, INC.
    Inventors: Alfredo C. Castro, James Martin Nolan, III, Sarah Jean Bethune, Corinne Marie Folberth
  • AHR INHIBITORS AND USES THEREOF
    Publication number: 20230026232
    Abstract: The present invention provides AHR inhibitors, formulations and unit dosage forms thereof, and methods of use thereof.
    Type: Application
    Filed: November 25, 2020
    Publication date: January 26, 2023
    Inventors: Alfredo C. Castro, James Martin NOLAN, III, Xiaoyan Michelle ZHANG, Jason SAGER
  • POLYMORPHIC COMPOUNDS AND USES THEREOF
    Publication number: 20210253579
    Abstract: The present invention provides freebase and salt forms, and compositions and methods thereof, useful for treating various conditions in which the aryl hydrocarbon receptor (AHR) is implicated, by the administration of small molecule therapeutics which act as inhibitors of AHR.
    Type: Application
    Filed: November 25, 2020
    Publication date: August 19, 2021
    Inventors: Alfredo C. CASTRO, James Martin NOLAN, III, Sarah Jean BETHUNE, Corinne Marie FOLBERTH
  • Therapeutic polymeric nanoparticles and methods of making and using same
    Patent number: 10577351
    Abstract: Described herein are polymeric nanoparticles that include a therapeutic agent which is 2-(3-((7-(3-(ethyl(2-hydroxyethyl)amino)propoxy)quinazolin-4-yl)amino)-1H-pyrazol-5-yl)-N-(3-fluorophenyl)acetamide (also known as AZD1152 hqpa) or a pharmaceutically acceptable salt thereof, and methods of making and using such therapeutic nanoparticles.
    Type: Grant
    Filed: June 27, 2018
    Date of Patent: March 3, 2020
    Assignee: ASTRAZENECA AB
    Inventors: Marianne Bernice Ashford, James Martin Nolan, III, Eyoung Shin, Young-Ho Song, Greg Troiano, Hong Wang
  • THERAPEUTIC POLYMERIC NANOPARTICLES AND METHODS OF MAKING AND USING SAME
    Publication number: 20190092757
    Abstract: Described herein are polymeric nanoparticles that include a therapeutic agent which is 2-(3-((7-(3-(ethyl(2-hydroxyethyl)amino)propoxy)quinazolin-4-yl)amino)-1H-pyrazol-5-yl)-N-(3-fluorophenyl)acetamide (also known as AZD1152 hqpa) or a pharmaceutically acceptable salt thereof, and methods of making and using such therapeutic nanoparticles.
    Type: Application
    Filed: June 27, 2018
    Publication date: March 28, 2019
    Applicant: ASTRAZENECA AB
    Inventors: Marianne Bernice ASHFORD, James Martin NOLAN, III, Eyoung SHIN, Young-Ho SONG, Greg TROIANO, Hong WANG
  • Therapeutic polymeric nanoparticles and methods of making and using same
    Patent number: 10047072
    Abstract: Described herein are polymeric nanoparticles that include a therapeutic agent which is 2-(3-((7-(3-(ethyl(2-hydroxyethyl)amino)propoxy)quinazolin-4-yl)amino)-1H-pyrazol-5-yl)-N-(3-fluorophenyl)acetamide (also known as AZD1152 hqpa) or a pharmaceutically acceptable salt thereof, and methods of making and using such therapeutic nanoparticles.
    Type: Grant
    Filed: September 15, 2014
    Date of Patent: August 14, 2018
    Assignee: ASTRAZENECA AB
    Inventors: Marianne Bernice Ashford, James Martin Nolan, III, Eyoung Shin, Young-Ho Song, Greg Troiano, Hong Wang
  • THERAPEUTIC POLYMERIC NANOPARTICLES AND METHODS OF MAKING AND USING SAME
    Publication number: 20150140104
    Abstract: Described herein are polymeric nanoparticles that include a therapeutic agent which is 2-(3-((7-(3-(ethyl(2-hydroxyethyl)amino)propoxy)quinazolin-4-yl)amino)-1H-pyrazol-5-yl)-N-(3-fluorophenyl)acetamide (also known as AZD1152 hqpa) or a pharmaceutically acceptable salt thereof, and methods of making and using such therapeutic nanoparticles.
    Type: Application
    Filed: September 15, 2014
    Publication date: May 21, 2015
    Applicant: ASTRAZENECA AB
    Inventors: Marianne Bernice ASHFORD, James Martin NOLAN III, Eyoung SHIN, Young-Ho SONG, Greg TROIANO, Hong WANG