Abstract: In one aspect, a method of estimating an HbA1c level is provided. The method may include obtaining a first and second glucose measurement, adding the first and the second glucose measurements to a glucose measurement data set, and calculating an estimated HbA1c level using at least the glucose measurement data set. In another aspect, a method of calculating a range of an estimated HbA1c level is provided. The method may comprise at least calculating an estimated HbA1c level and a standard deviation of the estimated HbA1c level using a glucose measurement data set, and combining the estimated HbA1c level with the standard deviation of the estimated HbA1c level to acquire the range of the estimated HbA1c level. In another aspect, a glucose monitoring device may display glycemic variability of an individual.

Abstract: A sensor, system, and method for detecting and correcting for an effect on an analyte indicator of an analyte sensor. The analyte indicator may have a first detectable property that varies in accordance with an analyte concentration and an effect on (e.g., degradation of) the analyte indicator. The analyte sensor may also include an interferent indicator having a second detectable property (e.g., absorption) that varies in accordance the effect on the analyte indicator. The analyte sensor may generate (i) an analyte measurement based on the first detectable property of the analyte indicator and (ii) an interferent measurement based on the second detectable property of the interferent indicator. The analyte sensor may be part of a system that also includes a transceiver. The transceiver may use the analyte and interferent measurements to calculate an analyte level.

Abstract: A sensing system including analyte sensing devices, an interface device, and shared communication device. The interface device may be configured to receive a power signal and generate power for powering the sensing devices and to convey data signals generated by the sensing devices. The sensing system may be configured to receive addressed and unaddressed commands. The sensing devices may be configured to perform activities (e.g., measurement sequences) in parallel in response to the unaddressed commands (e.g., unaddressed measurement commands). The sensing devices may be configured to only perform activities (e.g., conveying measurement data) in response to addressed commands (e.g., addressed read measurement data commands) if the sensing devices determine that the addressed commands are addressed to them.

Abstract: An analyte monitoring system and method. The analyte monitoring system may include an analyte sensor and a transceiver. The analyte sensor may include an analyte indicator that exhibits one or more detectable properties based on an amount or concentration of an analyte in proximity to the indicator. The transceiver may be configured to receive one or more measurements from the sensor. The transceiver may be configured to assess in real time a performance of the sensor based on at least the one or more measurements. The transceiver may be configured to determine whether the performance of the sensor is deficient based at least on the assessed performance of the sensor. The transceiver may be configured to calculate an analyte level based on at least the one or more sensor measurements. The transceiver may be configured to determine whether the calculated analyte level is a spike.

Abstract: Method and apparatus for locating an implant comprising magnetic material and/or a charge storage device in a living animal. The apparatus may include a magnetic field generator (e.g., an electromagnetic field generator) configured to generate a magnetic field (e.g., an electromagnetic field). The apparatus may include a sensor configured to detect changes in the magnetic field and to generate a sensor signal indicative of the changes in the magnetic field. The magnetic material and/or the charge storage device of the implant may cause changes to the magnetic field as the sensor is moved over the implant. The apparatus may include a computer configured to use the sensor signal to detect a location of the implant.

Abstract: A sensing system including analyte sensing devices, an interface device, and shared communication device. The interface device may be configured to receive a power signal and generate power for powering the sensing devices and to convey data signals generated by the sensing devices. The sensing system may be configured to receive addressed and unaddressed commands. The sensing devices may be configured to perform activities (e.g., measurement sequences) in parallel in response to the unaddressed commands (e.g., unaddressed measurement commands). The sensing devices may be configured to only perform activities (e.g., conveying measurement data) in response to addressed commands (e.g., addressed read measurement data commands) if the sensing devices determine that the addressed commands are addressed to them.

Abstract: An analyte monitoring system and method. The analyte monitoring system may include an analyte sensor and a transceiver. The analyte sensor may include an analyte indicator that exhibits one or more detectable properties based on an amount or concentration of an analyte in proximity to the indicator. The transceiver may be configured to receive one or more measurements from the sensor. The transceiver may be configured to assess in real time a performance of the sensor based on at least the one or more measurements. The transceiver may be configured to determine whether the performance of the sensor is deficient based at least on the assessed performance of the sensor. The transceiver may be configured to calculate an analyte level based on at least the one or more sensor measurements. The transceiver may be configured to determine whether the calculated analyte level is a spike.

Abstract: A sensor, system, and method for detecting and correcting for changes to an analyte indicator of an analyte sensor. The analyte indicator may be configured to exhibit a first detectable property that varies in accordance with an analyte concentration and an extent to which the analyte indicator has degraded. The analyte sensor may also include a degradation indicator configured to exhibit a second detectable property that varies in accordance with an extent to which the degradation indicator has degraded. The analyte sensor may generate (i) an analyte measurement based on the first detectable property exhibited by the analyte indicator and (ii) a degradation measurement based on the second detectable property exhibited by the degradation indicator. The analyte sensor may be part of a system that also includes a transceiver. The transceiver may use the analyte and degradation measurements to calculate an analyte level.

Abstract: A sensor, system, and method for detecting and correcting for changes to an analyte indicator of an analyte sensor. The analyte indicator may be configured to exhibit a first detectable property that varies in accordance with an analyte concentration and an extent to which the analyte indicator has degraded. The analyte sensor may also include a degradation indicator configured to exhibit a second detectable property that varies in accordance with an extent to which the degradation indicator has degraded. The analyte sensor may generate (i) an analyte measurement based on the first detectable property exhibited by the analyte indicator and (ii) a degradation measurement based on the second detectable property exhibited by the degradation indicator. The analyte sensor may be part of a system that also includes a transceiver. The transceiver may use the analyte and degradation measurements to calculate an analyte level.

Abstract: Disclosed are systems and methods for detecting analyte levels. These systems and methods may include a sensor configured for at least partial placement in an analyte-containing medium. The sensor may include one or more transducers and one or more diffusion barriers. The diffusion barriers may be arranged to delay diffusion of analyte to one transducer relative to another transducer. This delay may be used for purposes such as calculating and/or compensating for lag between a measured analyte level and a physiological analyte level of interest.

Abstract: An analyte monitoring system includes an analyte sensor, a transceiver, and a display device. The analyte sensor may include an analyte indicator that exhibits one or more detectable properties based on an amount or concentration of an analyte in proximity to the analyte indicator. The transceiver may receive first sensor data directly from the analyte sensor and may calculate first analyte information using at least the received first sensor data. The display device may receive second sensor data directly from the analyte sensor and calculates second analyte information using at least the received second sensor data. The transceiver may convey the first analyte information, and the display device may receive the first analyte information conveyed by the transceiver and display the first and second analyte information.

Abstract: An analyte monitoring system includes an analyte sensor, a transceiver, and a display device. The analyte sensor may include an analyte indicator that exhibits one or more detectable properties based on an amount or concentration of an analyte in proximity to the analyte indicator. The transceiver may receive first sensor data directly from the analyte sensor and may calculate first analyte information using at least the received first sensor data. The display device may receive second sensor data directly from the analyte sensor and calculates second analyte information using at least the received second sensor data. The transceiver may convey the first analyte information, and the display device may receive the first analyte information conveyed by the transceiver and display the first and second analyte information.

Abstract: A sensor, system, and method for detecting and correcting for an effect on an analyte indicator of an analyte sensor. The analyte indicator may be configured to exhibit a first detectable property that varies in accordance with an analyte concentration and an effect on (e.g., degradation of) the analyte indicator. The analyte sensor may also include an interferent indicator configured to exhibit a second detectable property (e.g., absorption) that varies in accordance the effect on the analyte indicator. The analyte sensor may generate (i) an analyte measurement based on the first detectable property exhibited by the analyte indicator and (ii) an interferent measurement based on the second detectable property exhibited by the interferent indicator. The analyte sensor may be part of a system that also includes a transceiver. The transceiver may use the analyte and interferent measurements to calculate an analyte level.

Abstract: Disclosed are systems and methods for detecting analyte levels. These systems and methods may include a sensor configured for at least partial placement in an analyte-containing medium. The sensor may include one or more transducers and one or more diffusion barriers. The diffusion barriers may be arranged to delay diffusion of analyte to one transducer relative to another transducer. This delay may be used for purposes such as calculating and/or compensating for lag between a measured analyte level and a physiological analyte level of interest.

Abstract: An improved analyte monitoring system having a sensor and a transceiver with improved communication and/or user interface capabilities. The transceiver may communicate with and power the sensor. The transceiver may receive one or more analyte measurements from the sensor and may calculate one or more analyte concentrations based on the received analyte measurements. The transceiver may generate analyte concentration trends, alerts, and/or alarms based on the calculated analyte concentrations. The system may also include a display device, which may be, for example, a smartphone and may be used to display analyte measurements received from the transceiver. The display device may execute a mobile medical application. The system may include a data management system, which may be web-based.

Abstract: An implantable device including a housing, circuitry within the housing, and a power source attached to the housing and electrically connected to the circuitry. The device may include electrically conductive connectors configured to electrically connect positive and negative terminals of the power source to the circuitry. The device may include a power source terminal enclosure attached to the power source and configured to enclose the positive and negative terminals of the power source. The power source terminal enclosure may include holes through which the electrically conductive connectors pass. The device may include a housing cap enclosure attached to the power source terminal enclosure and to an open end of the housing. The housing cap enclosure may enclose the circuitry within the housing and includes passages through which the electrically conductive connectors pass.

Abstract: Analyte monitoring methods and systems for interferent detection. The methods may include using one or more analyte detectors of an analyte sensor to generate one or more analyte measurements indicative of an analyte level in a first medium. The methods may include using one or more interferent detectors of the analyte sensor and/or one or more interferent sensors of a transceiver to generate one or more interferent measurements indicative of an interferent level in the first medium. The methods may include using a transceiver interface of the analyte sensor to convey the one or more analyte measurements and using a sensor interface of the transceiver to receive the one or more analyte measurements from the analyte sensor. The methods may include using the transceiver to calculate an analyte level in a second medium using at least the one or more analyte measurements and the one or more interferent measurements.

Abstract: A sensing system including analyte sensing devices, an interface device, and shared communication device. The interface device may be configured to receive a power signal and generate power for powering the sensing devices and to convey data signals generated by the sensing devices. The sensing system may be configured to receive addressed and unaddressed commands. The sensing devices may be configured to perform activities (e.g., measurement sequences) in parallel in response to the unaddressed commands (e.g., unaddressed measurement commands). The sensing devices may be configured to only perform activities (e.g., conveying measurement data) in response to addressed commands (e.g., addressed read measurement data commands) if the sensing devices determine that the addressed commands are addressed to them.

Abstract: A sensor, system, and method for detecting and correcting for changes to an analyte indicator of an analyte sensor. The analyte indicator may be configured to exhibit a first detectable property that varies in accordance with an analyte concentration and an extent to which the analyte indicator has degraded. The analyte sensor may also include a degradation indicator configured to exhibit a second detectable property that varies in accordance with an extent to which the degradation indicator has degraded. The analyte sensor may generate (i) an analyte measurement based on the first detectable property exhibited by the analyte indicator and (ii) a degradation measurement based on the second detectable property exhibited by the degradation indicator. The analyte sensor may be part of a system that also includes a transceiver. The transceiver may use the analyte and degradation measurements to calculate an analyte level.

Abstract: A system and method for measuring an amount of blood and/or clotting in a pocket around an implantable device. The system may include a first light source configured to emit light over a first wavelength range. The system may include a first photodetector configured to output a first signal indicative of an amount of the first light received by the first photodetector. The system may include the implantable device and an external device. The implantable device may include one of the first light source and the first photodetector, and the external device may include the other of the first light source and the first photodetector. In some embodiments, the external device may include a controller configured to calculate the amount of blood/or clotting in the pocket around the implantable device using at least a measurement of the first signal.