Abstract: A system for treating and/or diagnosing tissue from a tissue surface comprises: a console; an interface assembly; and a mobile device. The mobile device is configured to navigate a tissue surface and can comprise: a first tissue attachment assembly; a second tissue attachment assembly; and at least one articulation assembly. The interface assembly operably connects the console to the mobile device. The console is configured to manipulate the at least one articulation assembly via the interface assembly. The at least one articulation assembly is configured to navigate from a first tissue location to a second tissue location. The mobile device is configured to diagnose and/or treat tissue at the second tissue location. Methods of treating and/or diagnosing tissue are also described.

Abstract: Introduced here is a technology that enables a merchant to create customer-targeted, customized communications by use of a merchant platform executing on a financial service system. The merchant platform generates content for communications that is based on a particular customer segment. The customer segment includes one or more groups of customers segmented based on one or more attributes associated with each group of customers. An attribute is determined based on data collected by the financial service system, where the data is related to transaction data of a plurality of merchants.

Abstract: A method to perform continuous-wave NMR measurements of nuclear magnetization at high magnetic fields, above 2.5 T, without analog down-mixing is described. An FPGA controls a digital clock pulse which is used to stimulate a resonant circuit and provide a reference signal. An algorithm determines the real portion of a resonant circuit signal near the Larmor frequency of the species of interest using only two measurements of the waveform per cycle. The FPGA automatically alters a variable capacitance to tune the resonant circuit to the Larmor frequency.

Abstract: Embodiments of negative pressure wound therapy systems, apparatuses, and methods for operating the systems and apparatuses are disclosed. In some embodiments, the apparatus includes a negative pressure source, a connector port, at least one switch, and a controller. The negative pressure source is connected through the connector port to either (i) a wound dressing having a canister configured to store fluid aspirated from the wound or (ii) a wound dressing without a canister between the connector port and the wound dressing. The controller determines, based on a signal received from the at least one switch, whether the canister is positioned in the fluid flow path and adjusts one or more operational parameters of negative pressure wound therapy based on the determination. The switch is activated by the connection of either the canister or canisterless wound dressing to the apparatus.

Abstract: Provided herein are pharmaceutical formulations, methods for their production, and uses thereof. The pharmaceutical formulations comprise a salt of an optionally substituted dimethyltryptamine compound, a buffer, which is separate to the salt, and water. The formulations have pH values of from about 3.5 to about 6.5 and osmolalities of about 250 to about 350 mOsm/Kg. Such formulations are suitable for injection, being both stable and clinically acceptable, and have potential uses in the treatment of psychiatric or neurological disorders.

Abstract: Disclosed is an approach to differentiating between different particle types in samples flowing through microfluidics chips. A sample may have an initial proportion of a first cell type to a second cell type. An illuminating light source may emit a coherent light at the sample, and light leaving the chip in a first direction may be detected using a first light detector, and light leaving the chip in a second direction (e.g., orthogonal to the first direction) may be detected using a second light detector. The detected light may be fluorescence. An orientational feature of a plurality of cells in the sample may be determined based on the light detected by the detectors. Based on the orientational features and the detected light, a biasing operation may be performed for each cell in the sample to obtain a modified proportion of cell types in the sample.

Abstract: Provided herein are pharmaceutical formulations, methods for their production, and uses thereof. The pharmaceutical formulations comprise a salt of an optionally substituted dimethyltryptamine compound, a buffer, which is separate to the salt, and water. The formulations have pH values of from about 3.5 to about 6.5 and osmolalities of about 250 to about 350 mOsm/Kg. Such formulations are suitable for injection, being both stable and clinically acceptable, and have potential uses in the treatment of psychiatric or neurological disorders.

Abstract: Embodiments of negative pressure wound therapy systems, apparatuses, and methods for operating the systems and apparatuses are disclosed. In some embodiments, the apparatus includes a negative pressure source, a connector port, at least one switch, and a controller. The negative pressure source is connected through the connector port to either (i) a wound dressing having a canister configured to store fluid aspirated from the wound or (ii) a wound dressing without a canister between the connector port and the wound dressing. The controller determines, based on a signal received from the at least one switch, whether the canister is positioned in the fluid flow path and adjusts one or more operational parameters of negative pressure wound therapy based on the determination. The switch is activated by the connection of either the canister or canisterless wound dressing to the apparatus.

Abstract: A spout includes a base frame fittable about a designated package pour opening surface area, an opening assembly moveably coupled to the base frame and adapted to at least partially cut/rupture/open/pierce the pour opening surface area, and a control device configured to control the opening assembly. The control device comprises at least one interaction element connected to the opening assembly, at least one control ring rotatably coupled to the base frame and at least one interaction member connected/coupled to the control ring and configured to interact with the interaction element. In use, upon rotating the control ring, the interaction member interacts with the interaction element to induce translation of a cutter of the opening assembly for controlling the opening assembly from a rest configuration to an operative configuration and an axial end portion of the interaction member is arranged within a rotation plane fixed relative to the base frame.

Abstract: A package assembly (300, 400, 500) comprising a package (100, 302) arranged to hold a food product, wherein the package (100,302) comprises a rear section (140) provided with a longitudinal seal (LS), and an exoskeleton (308, 402, 502, 600, 700, 800, 900, 1000, 1100, 1200, 1300) attached to the rear section (140) of the package (100,302) such that an improved robustness is achieved and that the longitudinal seal (LS) is protected.

Abstract: Described herein are pharmaceutical formulations, methods for their production, and uses thereof. The pharmaceutical formulations comprise a salt of an optionally substituted dimethyltryptamine compound, a buffer, which is separate to the salt, and water. The formulations have pH values of from about 3.5 to about 6.5 and osmolalities of about 250 to about 350 mOsm/Kg. Such formulations are suitable for injection, being both stable and clinically acceptable, and have potential uses in the treatment of psychiatric or neurological disorders.

Abstract: Provided herein are pharmaceutical formulations, methods for their production, and uses thereof. The pharmaceutical formulations comprise a salt of an optionally substituted dimethyltryptamine compound, a buffer, which is separate to the salt, and water. The formulations have pH values of from about 3.5 to about 6.5 and osmolalities of about 250 to about 350 mOsm/Kg. Such formulations are suitable for injection, being both stable and clinically acceptable, and have potential uses in the treatment of psychiatric or neurological disorders.

Abstract: A method to perform continuous-wave NMR measurements of nuclear magnetization at high magnetic fields, above 2.5 T, without analog down-mixing is described. An FPGA controls a digital clock pulse which is used to stimulate a resonant circuit and provide a reference signal. An algorithm determines the real portion of a resonant circuit signal near the Larmor frequency of the species of interest using only two measurements of the waveform per cycle. The FPGA automatically alters a variable capacitance to tune the resonant circuit to the Larmor frequency.

Abstract: A method for electronically mining intellectual property using an associative discovery process may include determining a set of documents containing keywords and/or phrases associated with an industry trend of interest. The method may also include determining a feedback score for each document in the set, determining an optimal weighing scheme for the determined keywords and/or phrases using a statistical learning model and the feedback scores, ranking all documents in the set of documents according to the optimal weighing scheme, and providing results of the associative discovery process to a user.

Abstract: A method is provided for the automatic control of cycling speed in a human. The method comprises: estimating the subject's actual cycling speed using one or more sensors to thereby obtain a measured speed; determining an error comprising a difference between a desired speed and the measured speed; and outputting, to the subject, a stimulus frequency signal wherein the stimulus frequency signal is based on the error in such a manner that when the subject pedals in a manner that matches a frequency of the stimulus frequency signal, the subject's actual speed controllably tracks the desired speed.

Abstract: A method is provided for the automatic control of cycling speed in a human. The method comprises: estimating the subject's actual cycling speed using one or more sensors to thereby obtain a measured speed; determining an error comprising a difference between a desired speed and the measured speed; and outputting, to the subject, a stimulus frequency signal wherein the stimulus frequency signal is based on the error in such a manner that when the subject pedals in a manner that matches a frequency of the stimulus frequency signal, the subject's actual speed controllably tracks the desired speed.

Abstract: A device for verifying a subject includes: a device body comprising a processor and a biometric system; wherein the biometric system comprises a first image capture device and a second image capture device, in which the first image capture device is configured to define a spatial region and the second image capture device is configured to capture an image of a subject within said spatial region, and the processor is configured to conduct an identification process on the captured image of the subject within the spatial region.

Abstract: A toy exhaust device (10) for attachment to a rear stay (11) of the frame of a bicycle, the device (10) comprises an elongate body unit (13) having formations (14, 15) thereon shaped so that the body unit (13) is locatable against the surface (16) of the rear stay 11, which surface (16) faces out from the frame, an exhaust pipe (17) extending from the body unit (13) to the rear of the frame and away therefrom, when the body unit (13) is attached thereto. The device (10) is symmetrically disposed about a plane of division (18) of the device (10), in which plane of division the longitudinal axis of the body unit (13) lies, and such that, in use, when an exhaust device (10) is attached to each side of the frame one device (10) will be a mirror image of the other device (10).

Abstract: Embodiments of negative pressure wound therapy systems, apparatuses, and methods for operating the systems and apparatuses are disclosed. In some embodiments, the apparatus includes a negative pressure source, a connector port, at least one switch, and a controller. The negative pressure source is connected through the connector port to either (i) a wound dressing having a canister configured to store fluid aspirated from the wound or (ii) a wound dressing without a canister between the connector port and the wound dressing. The controller determines, based on a signal received from the at least one switch, whether the canister is positioned in the fluid flow path and adjusts one or more operational parameters of negative pressure wound therapy based on the determination. The switch is activated by the connection of either the canister or canisterless wound dressing to the apparatus.

Abstract: A method for electronically mining intellectual property using an associative discovery process may include determining a set of documents containing keywords and/or phrases associated with an industry trend of interest and, for each document, assigning a weight. The method may also include selecting a subset of the documents based at least upon the assigned weights, and determining a feedback score for each document in the subset. The method may further include determining an optimal weighing scheme for the determined keywords and/or phrases using a statistical learning model and the feedback scores, ranking all documents in the set of documents according to the optimal weighing scheme, and providing results of the associative discovery process to a user.