Patents by Inventor James McIninch
James McIninch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230040920Abstract: The disclosure relates to double-stranded ribonucleic acid (dsRNA) compositions targeting the DNAJB 1-PRKAC A fusion gene, and methods of using such dsRNA compositions to alter (e.g., inhibit) expression of DNAJB 1-PRKAC A fusion.Type: ApplicationFiled: October 30, 2020Publication date: February 9, 2023Applicant: ALNYLAM PHARMACEUTICALS, INC.Inventors: LEILA NOETZLI, HO-CHOU TU, PATRICK HASLETT, JAMES MCININCH
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Publication number: 20220389429Abstract: The disclosure relates to double-stranded ribonucleic acid (dsRNA) compositions targeting the UGT1a1 gene, and methods of using such dsRNA compositions to alter (e.g., inhibit) expression of UGT1a1.Type: ApplicationFiled: October 2, 2020Publication date: December 8, 2022Applicant: ALNYLAM PHARMACEUTICALS, INC.Inventors: DONALD FOSTER, JAMES MCININCH
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Publication number: 20220290152Abstract: The disclosure relates to double-stranded ribonucleic acid (dsRNA) compositions targeting the LECT2 gene, and methods of using such dsRNA compositions to alter (e.g., inhibit) expression of LECT2.Type: ApplicationFiled: September 2, 2020Publication date: September 15, 2022Applicant: ALNYLAM PHARMACEUTICALS, INC.Inventors: HO-CHOU TU, JAMES MCININCH
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Publication number: 20130333071Abstract: The present invention is in the field of plant biochemistry and genetics. More specifically the invention relates to nucleic acid molecules from plant cells, in particular, genomic DNA sequences from rice plants and nucleic acid molecules that contain markers, in particular, single nucleotide polymorphism (SNP) and repetitive element markers. In addition, the present invention provides nucleic acid molecules having regulatory elements or encoding proteins or fragments thereof. The invention also relates to proteins and fragments of proteins so encoded and antibodies capable of binding the proteins. The invention also relates to methods of using the nucleic acid molecules, markers, repetitive elements and fragments of repetitive elements, regulatory elements, proteins and fragments of proteins, and antibodies, for example for genome mapping, gene identification and analysis, plant breeding, preparation of constructs for use in plant gene expression, and transgenic plants.Type: ApplicationFiled: January 10, 2011Publication date: December 12, 2013Applicant: MONSANTO TECHNOLOGY LLCInventors: Andrey A. Boukharov, Yongwei Cao, David K. Kovalic, Jingdong Liu, James McIninch, Wei Wu
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Publication number: 20110014706Abstract: The present invention relates to nucleic acid sequences from the dicotyldonus plant Arabidopsis thaliana and, in particular, to genomic DNA sequences. The invention encompasses nucleic acid molecules present in non-coding regions as well as nucleic acid molecules that encode proteins and fragments of proteins. In addition, proteins and fragments of proteins so encoded and antibodies capable of binding the proteins are encompassed by the present invention. The invention also encompasses oligonucleotides including primers, e.g. useful for amplifying nucleic acid molecules, and collections of nucleic acid molecules and oligonucleotides, e.g. in microarrays. The invention also provides constructs and transgenic cells and organisms comprising nucleic acid molecules of the invention.Type: ApplicationFiled: December 28, 1999Publication date: January 20, 2011Applicant: MONSANTO TECHNOLOGY LLCInventors: Yongwei CAO, David KOVALIC, Jingdong LIU, James MCININCH, Steven ROUNSLEY, Sai SUBRAMANIAM, Roger WIEGAND
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Patent number: 7868149Abstract: The present invention is in the field of plant biochemistry and genetics. More specifically the invention relates to nucleic acid molecules from plant cells, in particular, genomic DNA sequences from rice plants and nucleic acid molecules that contain markers, in particular, single nucleotide polymorphism (SNP) and repetitive element markers. In addition, the present invention provides nucleic acid molecules having regulatory elements or encoding proteins or fragments thereof. The invention also relates to proteins and fragments of proteins so encoded and antibodies capable of binding the proteins. The invention also relates to methods of using the nucleic acid molecules, markers, repetitive elements and fragments of repetitive elements, regulatory elements, proteins and fragments of proteins, and antibodies, for example for genome mapping, gene identification and analysis, plant breeding, preparation of constructs for use in plant gene expression, and transgenic plants.Type: GrantFiled: July 24, 2006Date of Patent: January 11, 2011Assignee: Monsanto Technology LLCInventors: Andrey A. Boukharov, Yongwei Cao, David K. Kovalic, Jingdong Liu, James McIninch, Wei Wu
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Publication number: 20100293663Abstract: Polynucleotides useful for improvement of plants are provided. In particular, polynucleotide sequences are provided from plant sources. Polypeptides encoded by the polynucleotide sequences are also provided. The disclosed polynucleotides and polypeptides find use in production of transgenic plants to produce plants having improved properties.Type: ApplicationFiled: July 2, 2003Publication date: November 18, 2010Inventors: Thomas LA ROSA, David KOVALIC, Yihua ZHOU, Yongwei CAO, Mark ABAD, Scott ANDERSEN, Robert BUEHLER, Joseph BYRUM, Nordine CHEIKH, Timothy CONNER, Brian COOMBS, Stanton DOTSON, Patrice DUBOIS, Michael EDGERTON, Dane FISHER, Kristine HARDEMAN, Gregory HECK, Gregory HINKLE, Raghunath LALGUDI, Jingdong LIU, Linda LUTFIYYA, Debbie MAHADEO, James MASUCCI, James MCININCH, Philip MILLER, Donald NELSON, Mingsheng PENG, Thomas RUFF, Hridayabhiranjan SHUKLA, Joshua STEIN, Michael THOMPSON, Kunsheng WU
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Publication number: 20100255584Abstract: The present invention relates to nucleic acid sequences from the dicotyldonus plant Arabidopsis thaliana and, in particular, to genomic DNA sequences. The invention encompasses nucleic acid molecules present in non-coding regions as well as nucleic acid molecules that encode proteins and fragments of proteins. In addition, proteins and fragments of proteins so encoded and antibodies capable of binding the proteins are encompassed by the present invention. The invention also encompasses oligonucleotides including primers, e.g. useful for amplifying nucleic acid molecules, and collections of nucleic acid molecules and oligonucleotides, e.g. in microarrays. The invention also provides constructs and transgenic cells and organisms comprising nucleic acid molecules of the invention.Type: ApplicationFiled: December 28, 1999Publication date: October 7, 2010Applicant: MONSANTO TECHNOLOGY LLCInventors: Cao YONGWEI, David KOVALIC, Jingdong LIU, James MCININCH, Steven ROUNSLEY, Sai SUBRAMANIAM, Roger WIEGAND
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Publication number: 20080263721Abstract: The present invention discloses rice genomic promoter sequences. The promoters are particularly suited for use in rice and other cereal crops. Methods of modifying, producing, and using the promoters are also disclosed. The invention further discloses compositions, transformed host cells, transgenic plants, and seeds containing the rice genomic promoter sequences, and methods for preparing and using the same.Type: ApplicationFiled: November 13, 2006Publication date: October 23, 2008Inventors: Andrey Boukharov, Yongwei Cao, Stanton Dotson, Jeffrey Koshi, David Kovalic, Jingdong Liu, James McIninch, Wei Wu
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Publication number: 20080114160Abstract: The present invention is in the field of plant biochemistry and genetics. More specifically the invention relates to nucleic acid molecules from plant cells, in particular, genomic DNA sequences from rice plants and nucleic acid molecules that contain markers, in particular, single nucleotide polymorphism (SNP) and repetitive element markers. In addition, the present invention provides nucleic acid molecules having regulatory elements or encoding proteins or fragments thereof. The invention also relates to proteins and fragments of proteins so encoded and antibodies capable of binding the proteins. The invention also relates to methods of using the nucleic acid molecules, markers, repetitive elements and fragments of repetitive elements, regulatory elements, proteins and fragments of proteins, and antibodies, for example for genome mapping, gene identification and analysis, plant breeding, preparation of constructs for use in plant gene expression, and transgenic plants.Type: ApplicationFiled: October 31, 2000Publication date: May 15, 2008Inventors: Andrey Boukharov, Yongwei Cao, David Kovalic, Jingdong Liu, James McIninch, Wei Wu
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Publication number: 20070118921Abstract: The present invention discloses rice genomic promoter sequences. The promoters are particularly suited for use in rice and other cereal crops. Methods of modifying, producing, and using the promoters are also disclosed. The invention further discloses compositions, transformed host cells, transgenic plants, and seeds containing the rice genomic promoter sequences, and methods for preparing and using the same.Type: ApplicationFiled: November 13, 2006Publication date: May 24, 2007Inventors: Andrey Boukharov, Yongwei Cao, Stanton Dotson, Jeffrey Koshi, David Kovalic, Jingdong Liu, James McIninch, Wei Wu
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Publication number: 20070039076Abstract: The present invention is in the field of plant biochemistry and genetics. More specifically the invention relates to nucleic acid molecules from plant cells, in particular, genomic DNA sequences from rice plants and nucleic acid molecules that contain markers, in particular, single nucleotide polymorphism (SNP) and repetitive element markers. In addition, the present invention provides nucleic acid molecules having regulatory elements or encoding proteins or fragments thereof. The invention also relates to proteins and fragments of proteins so encoded and antibodies capable of binding the proteins. The invention also relates to methods of using the nucleic acid molecules, markers, repetitive elements and fragments of repetitive elements, regulatory elements, proteins and fragments of proteins, and antibodies, for example for genome mapping, gene identification and analysis, plant breeding, preparation of constructs for use in plant gene expression, and transgenic plants.Type: ApplicationFiled: July 24, 2006Publication date: February 15, 2007Inventors: Andrey Boukharov, Yongwei Cao, David Kovalic, Jingdong Liu, James McIninch, Wei Wu
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Publication number: 20070020621Abstract: The present invention discloses rice genomic promoter sequences. The promoters are particularly suited for use in rice and other cereal crops. Methods of modifying, producing, and using the promoters are also disclosed. The invention further discloses compositions, transformed host cells, transgenic plants, and seeds containing the rice genomic promoter sequences, and methods for preparing and using the same.Type: ApplicationFiled: March 23, 2001Publication date: January 25, 2007Inventors: Andrey Boukharov, Yongwei Cao, Stanton Dotson, Jeffrey Koshi, David Kovalic, Jingdong Liu, James McIninch, Wei Wu