Patents by Inventor James McIninch

James McIninch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230040920
    Abstract: The disclosure relates to double-stranded ribonucleic acid (dsRNA) compositions targeting the DNAJB 1-PRKAC A fusion gene, and methods of using such dsRNA compositions to alter (e.g., inhibit) expression of DNAJB 1-PRKAC A fusion.
    Type: Application
    Filed: October 30, 2020
    Publication date: February 9, 2023
    Applicant: ALNYLAM PHARMACEUTICALS, INC.
    Inventors: LEILA NOETZLI, HO-CHOU TU, PATRICK HASLETT, JAMES MCININCH
  • Publication number: 20220389429
    Abstract: The disclosure relates to double-stranded ribonucleic acid (dsRNA) compositions targeting the UGT1a1 gene, and methods of using such dsRNA compositions to alter (e.g., inhibit) expression of UGT1a1.
    Type: Application
    Filed: October 2, 2020
    Publication date: December 8, 2022
    Applicant: ALNYLAM PHARMACEUTICALS, INC.
    Inventors: DONALD FOSTER, JAMES MCININCH
  • Publication number: 20220290152
    Abstract: The disclosure relates to double-stranded ribonucleic acid (dsRNA) compositions targeting the LECT2 gene, and methods of using such dsRNA compositions to alter (e.g., inhibit) expression of LECT2.
    Type: Application
    Filed: September 2, 2020
    Publication date: September 15, 2022
    Applicant: ALNYLAM PHARMACEUTICALS, INC.
    Inventors: HO-CHOU TU, JAMES MCININCH
  • Publication number: 20130333071
    Abstract: The present invention is in the field of plant biochemistry and genetics. More specifically the invention relates to nucleic acid molecules from plant cells, in particular, genomic DNA sequences from rice plants and nucleic acid molecules that contain markers, in particular, single nucleotide polymorphism (SNP) and repetitive element markers. In addition, the present invention provides nucleic acid molecules having regulatory elements or encoding proteins or fragments thereof. The invention also relates to proteins and fragments of proteins so encoded and antibodies capable of binding the proteins. The invention also relates to methods of using the nucleic acid molecules, markers, repetitive elements and fragments of repetitive elements, regulatory elements, proteins and fragments of proteins, and antibodies, for example for genome mapping, gene identification and analysis, plant breeding, preparation of constructs for use in plant gene expression, and transgenic plants.
    Type: Application
    Filed: January 10, 2011
    Publication date: December 12, 2013
    Applicant: MONSANTO TECHNOLOGY LLC
    Inventors: Andrey A. Boukharov, Yongwei Cao, David K. Kovalic, Jingdong Liu, James McIninch, Wei Wu
  • Publication number: 20110014706
    Abstract: The present invention relates to nucleic acid sequences from the dicotyldonus plant Arabidopsis thaliana and, in particular, to genomic DNA sequences. The invention encompasses nucleic acid molecules present in non-coding regions as well as nucleic acid molecules that encode proteins and fragments of proteins. In addition, proteins and fragments of proteins so encoded and antibodies capable of binding the proteins are encompassed by the present invention. The invention also encompasses oligonucleotides including primers, e.g. useful for amplifying nucleic acid molecules, and collections of nucleic acid molecules and oligonucleotides, e.g. in microarrays. The invention also provides constructs and transgenic cells and organisms comprising nucleic acid molecules of the invention.
    Type: Application
    Filed: December 28, 1999
    Publication date: January 20, 2011
    Applicant: MONSANTO TECHNOLOGY LLC
    Inventors: Yongwei CAO, David KOVALIC, Jingdong LIU, James MCININCH, Steven ROUNSLEY, Sai SUBRAMANIAM, Roger WIEGAND
  • Patent number: 7868149
    Abstract: The present invention is in the field of plant biochemistry and genetics. More specifically the invention relates to nucleic acid molecules from plant cells, in particular, genomic DNA sequences from rice plants and nucleic acid molecules that contain markers, in particular, single nucleotide polymorphism (SNP) and repetitive element markers. In addition, the present invention provides nucleic acid molecules having regulatory elements or encoding proteins or fragments thereof. The invention also relates to proteins and fragments of proteins so encoded and antibodies capable of binding the proteins. The invention also relates to methods of using the nucleic acid molecules, markers, repetitive elements and fragments of repetitive elements, regulatory elements, proteins and fragments of proteins, and antibodies, for example for genome mapping, gene identification and analysis, plant breeding, preparation of constructs for use in plant gene expression, and transgenic plants.
    Type: Grant
    Filed: July 24, 2006
    Date of Patent: January 11, 2011
    Assignee: Monsanto Technology LLC
    Inventors: Andrey A. Boukharov, Yongwei Cao, David K. Kovalic, Jingdong Liu, James McIninch, Wei Wu
  • Publication number: 20100293663
    Abstract: Polynucleotides useful for improvement of plants are provided. In particular, polynucleotide sequences are provided from plant sources. Polypeptides encoded by the polynucleotide sequences are also provided. The disclosed polynucleotides and polypeptides find use in production of transgenic plants to produce plants having improved properties.
    Type: Application
    Filed: July 2, 2003
    Publication date: November 18, 2010
    Inventors: Thomas LA ROSA, David KOVALIC, Yihua ZHOU, Yongwei CAO, Mark ABAD, Scott ANDERSEN, Robert BUEHLER, Joseph BYRUM, Nordine CHEIKH, Timothy CONNER, Brian COOMBS, Stanton DOTSON, Patrice DUBOIS, Michael EDGERTON, Dane FISHER, Kristine HARDEMAN, Gregory HECK, Gregory HINKLE, Raghunath LALGUDI, Jingdong LIU, Linda LUTFIYYA, Debbie MAHADEO, James MASUCCI, James MCININCH, Philip MILLER, Donald NELSON, Mingsheng PENG, Thomas RUFF, Hridayabhiranjan SHUKLA, Joshua STEIN, Michael THOMPSON, Kunsheng WU
  • Publication number: 20100255584
    Abstract: The present invention relates to nucleic acid sequences from the dicotyldonus plant Arabidopsis thaliana and, in particular, to genomic DNA sequences. The invention encompasses nucleic acid molecules present in non-coding regions as well as nucleic acid molecules that encode proteins and fragments of proteins. In addition, proteins and fragments of proteins so encoded and antibodies capable of binding the proteins are encompassed by the present invention. The invention also encompasses oligonucleotides including primers, e.g. useful for amplifying nucleic acid molecules, and collections of nucleic acid molecules and oligonucleotides, e.g. in microarrays. The invention also provides constructs and transgenic cells and organisms comprising nucleic acid molecules of the invention.
    Type: Application
    Filed: December 28, 1999
    Publication date: October 7, 2010
    Applicant: MONSANTO TECHNOLOGY LLC
    Inventors: Cao YONGWEI, David KOVALIC, Jingdong LIU, James MCININCH, Steven ROUNSLEY, Sai SUBRAMANIAM, Roger WIEGAND
  • Publication number: 20080263721
    Abstract: The present invention discloses rice genomic promoter sequences. The promoters are particularly suited for use in rice and other cereal crops. Methods of modifying, producing, and using the promoters are also disclosed. The invention further discloses compositions, transformed host cells, transgenic plants, and seeds containing the rice genomic promoter sequences, and methods for preparing and using the same.
    Type: Application
    Filed: November 13, 2006
    Publication date: October 23, 2008
    Inventors: Andrey Boukharov, Yongwei Cao, Stanton Dotson, Jeffrey Koshi, David Kovalic, Jingdong Liu, James McIninch, Wei Wu
  • Publication number: 20080114160
    Abstract: The present invention is in the field of plant biochemistry and genetics. More specifically the invention relates to nucleic acid molecules from plant cells, in particular, genomic DNA sequences from rice plants and nucleic acid molecules that contain markers, in particular, single nucleotide polymorphism (SNP) and repetitive element markers. In addition, the present invention provides nucleic acid molecules having regulatory elements or encoding proteins or fragments thereof. The invention also relates to proteins and fragments of proteins so encoded and antibodies capable of binding the proteins. The invention also relates to methods of using the nucleic acid molecules, markers, repetitive elements and fragments of repetitive elements, regulatory elements, proteins and fragments of proteins, and antibodies, for example for genome mapping, gene identification and analysis, plant breeding, preparation of constructs for use in plant gene expression, and transgenic plants.
    Type: Application
    Filed: October 31, 2000
    Publication date: May 15, 2008
    Inventors: Andrey Boukharov, Yongwei Cao, David Kovalic, Jingdong Liu, James McIninch, Wei Wu
  • Publication number: 20070118921
    Abstract: The present invention discloses rice genomic promoter sequences. The promoters are particularly suited for use in rice and other cereal crops. Methods of modifying, producing, and using the promoters are also disclosed. The invention further discloses compositions, transformed host cells, transgenic plants, and seeds containing the rice genomic promoter sequences, and methods for preparing and using the same.
    Type: Application
    Filed: November 13, 2006
    Publication date: May 24, 2007
    Inventors: Andrey Boukharov, Yongwei Cao, Stanton Dotson, Jeffrey Koshi, David Kovalic, Jingdong Liu, James McIninch, Wei Wu
  • Publication number: 20070039076
    Abstract: The present invention is in the field of plant biochemistry and genetics. More specifically the invention relates to nucleic acid molecules from plant cells, in particular, genomic DNA sequences from rice plants and nucleic acid molecules that contain markers, in particular, single nucleotide polymorphism (SNP) and repetitive element markers. In addition, the present invention provides nucleic acid molecules having regulatory elements or encoding proteins or fragments thereof. The invention also relates to proteins and fragments of proteins so encoded and antibodies capable of binding the proteins. The invention also relates to methods of using the nucleic acid molecules, markers, repetitive elements and fragments of repetitive elements, regulatory elements, proteins and fragments of proteins, and antibodies, for example for genome mapping, gene identification and analysis, plant breeding, preparation of constructs for use in plant gene expression, and transgenic plants.
    Type: Application
    Filed: July 24, 2006
    Publication date: February 15, 2007
    Inventors: Andrey Boukharov, Yongwei Cao, David Kovalic, Jingdong Liu, James McIninch, Wei Wu
  • Publication number: 20070020621
    Abstract: The present invention discloses rice genomic promoter sequences. The promoters are particularly suited for use in rice and other cereal crops. Methods of modifying, producing, and using the promoters are also disclosed. The invention further discloses compositions, transformed host cells, transgenic plants, and seeds containing the rice genomic promoter sequences, and methods for preparing and using the same.
    Type: Application
    Filed: March 23, 2001
    Publication date: January 25, 2007
    Inventors: Andrey Boukharov, Yongwei Cao, Stanton Dotson, Jeffrey Koshi, David Kovalic, Jingdong Liu, James McIninch, Wei Wu