Abstract: The invention describes improved methods and compositions for producing a recombinant protein, e.g., an antibody, in mammalian cell culture. In addition, the invention provides improved cell culture media, including improved production media, feed solutions, and combination feeds, which may be used to improve protein productivity in mammalian cell culture.

Abstract: Methods are provided for the production of gram to kilogram quantities of pro-EP-B2 (proenzyme form of EP-B2) in a lyophilized form. The methods include scalable fermentation, refolding and purification processes, which processes may be combined with lyophilization to yield a stable product.

Abstract: The invention describes improved methods and compositions for producing a recombinant protein, e.g., an antibody, in mammalian cell culture. In addition, the invention provides improved cell culture media, including improved production media, feed solutions, and combination feeds, which may be used to improve protein productivity in mammalian cell culture.

Abstract: A cap facility for a medical cable having a terminal defining a rimmed chamber containing electrical contacts. The facility has a frame that connects to the terminal. An arm is connected to the frame, and is movable between a first closed position and a second open position. The arm is biased to the closed position, and has a cap adapted to enclose the rimmed chamber when the arm is in the closed position. The cap has an arcuate motion path between the open position and an intermediate position proximate to the closed position, and an initial motion path deviating from the arcuate path, such that the cap moves away from the rim initially upon departing from the closed position. The facility may have a camming mechanism that provides the path.

Abstract: A transversal equalizer is included in the luminance channel of a television receiver. Delayed video signals developed at taps of the transversal equalizer are combined to provide an output signal including preshoots and overshoots to accentuate amplitude transitions in the video signal so that, for example, a tonal transition from black to white is blacker than it normally would be just prior to the transition, and whiter than it normally would be just after the transition. The transversal equalizer includes provisions for selectively combining portions of predetermined delayed signals dependent upon the direction of the amplitude transitions such that preshoots and overshoots in one direction, e.g., the white direction, are relatively compressed or otherwise suppressed with respect to preshoots and overshoots in the other, i.e., black, direction.