Patents by Inventor James McKean
James McKean has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230293450Abstract: The invention relates to a fibrous composite material comprising a nonfibrous component having a water content of less than 10 wt. %; and a fibrous component comprising a porous scaffold of a plurality of electrospun polymeric fibers; wherein the nonfibrous component is a linear or branched, water-soluble, synthetic or natural polymer dispersed on the porous scaffold; and wherein at least 50% by weight of the fibrous composite material is the fibrous component. The fibrous composite material is useful in therapy, for instance, as a synthetic or substitute amniotic membrane. It may be used in the prevention and/or treatment of various trauma induced and chronic wounds and in ophthalmology.Type: ApplicationFiled: July 28, 2021Publication date: September 21, 2023Inventors: Robert James McKean, Gianpaolo Bruti, Teodor-Matei Cirstea, Marco Thio, Mehri Behbehani
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Patent number: 11394782Abstract: A flight management system of the present disclosure has an internal network that uses an open architecture concept with no single point of failure of critical system and which is cyber secure for aviation assets. A flight management system of the present disclosure comprises an internal network operating on an aircraft, and the internal network communicatively coupled to an external network via a firewall. The flight management system further has a primary system installed on the aircraft, which is initially active, and the primary system has a first weapons domain communicatively coupled to the internal network, a first flight domain communicatively coupled to the internal network, and a first communications domain communicatively coupled to the internal network.Type: GrantFiled: November 17, 2019Date of Patent: July 19, 2022Inventors: Daniel Donahue, James McKean
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Publication number: 20220071920Abstract: The invention relates to a therapeutic composition comprising an inner portion and a biocompatible membrane fully or partially surrounding the inner portion. The biocompatible membrane comprises at least two layers: a first layer of a porous, nonwoven network of thermoplastic polyurethane polymer fibers formed by electrospinning and having a porosity of greater than or equal to 50%; an average pore diameter of less than 5 ?m; and has a thickness in the range 10 to 250 ?m; and a second layer of a porous, nonwoven network of thermoplastic polymer fibers formed by electrospinning. The second layer has a mean average fiber diameter of the second layer is greater than the mean average fiber diameter in the first layer, and/or wherein the average pore diameter of the second layer is greater than the average pore diameter of the first layer. The inner portion comprises a therapeutic agent. The invention also relates to uses of the membrane and therapeutic composition, for instance, to encapsulate therapeutic cells.Type: ApplicationFiled: October 1, 2019Publication date: March 10, 2022Inventors: Robert James McKean, Teodor-Matei Cirstea, Brendan Robb
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Publication number: 20210176316Abstract: A flight management system of the present disclosure has an internal network that uses an open architecture concept with no single point of failure of critical system and which is cyber secure for aviation assets. A flight management system of the present disclosure comprises an internal network operating on an aircraft, and the internal network communicatively coupled to an external network via a firewall. The flight management system further has a primary system installed on the aircraft, which is initially active, and the primary system has a first weapons domain communicatively coupled to the internal network, a first flight domain communicatively coupled to the internal network, and a first communications domain communicatively coupled to the internal network.Type: ApplicationFiled: November 17, 2019Publication date: June 10, 2021Inventors: Daniel Donahue, James McKean
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Publication number: 20210008253Abstract: The invention relates to an elongate scaffold comprising: an inner portion comprising a polymer; and an outer portion comprising a porous, nonwoven network of polymer fibers, wherein the packing density of the inner portion is greater than the packing density of the outer portion; wherein the inner portion (a) comprises a plurality of polymer fibers twisted around one another or (b) is a solid core comprising the polymer. The invention also relates to a scaffold precursor and a process for producing a scaffold, comprising twisting a scaffold precursor of the invention along its length. Further provided is a hybrid composition comprising the scaffold and cells and/or an active agent such as a drug, a nucleic acid, a nucleotide, a protein, a polypeptide, or an exosome.Type: ApplicationFiled: January 29, 2019Publication date: January 14, 2021Inventors: Robert James McKean, Brendan John Robb, Teodor-Matei Cirstea
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Publication number: 20190032007Abstract: The invention provides a microscaffold comprising a porous particle, which particle: (a) comprises a three dimensional network of fibres, which fibres comprise a polymer, and (b) has a particle size of less than or equal to 2000 ?m. Further provided is a composition, which composition comprises a microscaffold of the invention or a plurality of microscaffolds of the invention. The invention also provides a multi-well assay plate comprising: a plurality of sample wells, and a composition of the invention in at least one of the sample wells. The microscaffold, composition or multi-well plate may be used for regenerative medicine, tissue engineering, screening compounds for biological use or drug screening. The microscaffold may further comprise a magnetic material, and the invention additionally provides a method of manipulating one or more such microscaffolds.Type: ApplicationFiled: November 23, 2016Publication date: January 31, 2019Inventors: Robert James MCKEAN, Gary ALLENBY, Erik Léon Victor FABRE DE LA RIPELLE
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Publication number: 20150283543Abstract: The invention provides a multi-well plate, comprising: a plate base, which defines the bottom of a plurality of sample wells; a scaffold layer disposed on the plate base, which scaffold layer provides a porous three-dimensional network of polymer nanofibres in each of said sample wells; and a plate frame, which defines the side walls of said sample wells; wherein the plate frame is bonded to the plate base through the scaffold layer. The invention further provides a process for producing the multi-well assay plate. Further provided is a scaffold which comprises a porous three dimensional network of electrospun polymer nanofibres, wherein the mean diameter of the polymer nanofibres is from 500 nm to 10 ?m. A process for producing the scaffold is also provided, as are various uses of the multi-well plate and the scaffold in drug screening, regenerative medicine and tissue engineering.Type: ApplicationFiled: February 7, 2013Publication date: October 8, 2015Applicant: The Electrospinning Company, Ltd.Inventor: Robert James McKean
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Patent number: 8818482Abstract: An electrode patch monitoring device that enables fast and accurate application is described. According to some embodiments, the electrode patch monitoring device comprises an array of electrodes for monitoring bioelectrical data that are formed on a flexible substrate. The electrode patch monitoring device may be available in a plurality of sizes, and various methods are provided for selecting an appropriate size according to the physiology of a patient. Methods for applying the electrode patch monitoring device to the patient's body are also provided.Type: GrantFiled: May 15, 2009Date of Patent: August 26, 2014Inventors: Paul David Phillips, Brian McGregor, Wesley James McKean
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Publication number: 20110190615Abstract: An electrode patch monitoring device that enables fast and accurate application is described. According to some embodiments, the electrode patch monitoring device comprises an array of electrodes for monitoring bioelectrical data that are formed on a flexible substrate. The electrode patch monitoring device may be available in a plurality of sizes, and various methods are provided for selecting an appropriate size according to the physiology of a patient. Methods for applying the electrode patch monitoring device to the patient's body are also provided.Type: ApplicationFiled: May 15, 2009Publication date: August 4, 2011Inventors: Paul David Phillips, Brian McGregor, Wesley James McKean
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Patent number: D552326Type: GrantFiled: October 11, 2005Date of Patent: October 9, 2007Assignee: Conopco, Inc.Inventors: Craig Luther Evans, Brian James McKean
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Patent number: D553326Type: GrantFiled: October 11, 2005Date of Patent: October 23, 2007Assignee: Conopco, Inc.Inventors: Craig Luther Evans, Brian James McKean
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Patent number: D598110Type: GrantFiled: May 16, 2008Date of Patent: August 11, 2009Assignee: Heartscape Technologies, Inc.Inventors: Paul David Phillips, Brian McGregor, Wesley James McKean
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Patent number: D598111Type: GrantFiled: May 16, 2008Date of Patent: August 11, 2009Assignee: Heartscape Technologies, Inc.Inventors: Paul David Phillips, Brian McGregor, Wesley James McKean
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Patent number: D598112Type: GrantFiled: May 16, 2008Date of Patent: August 11, 2009Assignee: Heartscape Technologies, Inc.Inventors: Paul David Phillips, Brian McGregor, Wesley James McKean
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Patent number: D600351Type: GrantFiled: May 16, 2008Date of Patent: September 15, 2009Assignee: Heartscape Technologies, Inc.Inventors: Paul David Phillips, Brian McGregor, Wesley James McKean
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Patent number: D605774Type: GrantFiled: November 14, 2008Date of Patent: December 8, 2009Assignee: Heartscape Technologies, Inc.Inventors: Paul David Phillips, Brian McGregor, Wesley James McKean
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Patent number: D606660Type: GrantFiled: November 14, 2008Date of Patent: December 22, 2009Assignee: Heartscape Technologies, Inc.Inventors: Paul David Phillips, Brian McGregor, Wesley James McKean
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Patent number: D607570Type: GrantFiled: November 14, 2008Date of Patent: January 5, 2010Assignee: Heartscape Technologies, Inc.Inventors: Paul David Phillips, Brian McGregor, Wesley James McKean