Abstract: Disclosed herein are dynamic multi-organ plates comprising two or more wells, wherein the wells are configured for cell or tissue culture growth; at least one transwell tube in fluid communication with the two or more wells; and a pump in fluid communication with the at least one transwell tube.

Abstract: Disclosed herein are dynamic multi-organ plates comprising two or more wells, wherein the wells are configured for cell or tissue culture growth; at least one transwell tube in fluid communication with the two or more wells; and a pump in fluid communication with the at least one transwell tube.

Abstract: The IONTOX endocrine field tester (EFT) provides an easy method for determining the presence, type, and amount of endocrine active chemicals. By developing a bead/receptor/column/reagent for only the target hormones, it is possible to detect a broad range of endocrine active materials for each receptor type. The EFT kit will provide the first simple method for monitoring environmental water systems that can be done in the field. Similar columns can also be prepared for androgens and for thyroid hormones. This means that the same technology can be applied to several different endocrine targets and the market and revenue significantly expanded.

Abstract: Disclosed herein are dynamic multi-organ plates comprising two or more wells, wherein the wells are configured for cell or tissue culture growth; at least one transwell tube in fluid communication with the two or more wells; and a pump in fluid communication with the at least one transwell tube.

Abstract: Disclosed herein are dynamic multi-organ plates comprising two or more wells, wherein the wells are configured for cell or tissue culture growth; at least one transwell tube in fluid communication with the two or more wells; and a pump in fluid communication with the at least one transwell tube.

Abstract: The IONTOX endocrine field tester (EFT) provides an easy method for determining the presence, type, and amount of endocrine active chemicals. By developing a bead/receptor/column/reagent for only the target hormones, it is possible to detect a broad range of endocrine active materials for each receptor type. The EFT kit will provide the first simple method for monitoring environmental water systems that can be done in the field. Similar columns can also be prepared for androgens and for thyroid hormones. This means that the same technology can be applied to several different endocrine targets and the market and revenue significantly expanded.

Abstract: Disclosed herein are dynamic multi-organ plates comprising two or more wells, wherein the wells are configured for cell or tissue culture growth; at least one transwell tube in fluid communication with the two or more wells; and a pump in fluid communication with the at least one transwell tube.

Abstract: An apparatus and method for synchronous communications using a serial data stream employs a housing with a controller and a back plane. The housing accepts one or more modules for interconnection with the back plane. The back plane distributes power to the modules and provides a communication link from the controller to each module. Each communication link includes a data out line, a data in line and a clock line, where each clock line is derived from one clock source.

Abstract: The present invention provides methods of determining a level of toxicity of a given compound based on in vitro assays. The present invention provides particular methods of determining organ-specific toxicity and species-specific toxicity of a given compound based on in vitro assays. In addition, the present invention provides methods of determining a level of toxicity in normal tissue for an anti-tumor compound. The methods include providing at least one cell type and culturing the cell type in the presence of at least one concentration of the chemical compound, measuring at least one indicator of cell health at the at least one concentration of compound for the at least one cell type, and performing a concentration response analysis, from which a toxic concentration can be determined.

Abstract: An apparatus and method for synchronous communications using a serial data stream employs a housing with a controller and a back plane. The housing accepts one or more modules for interconnection with the back plane. The back plane distributes power to the modules and provides a communication link from the controller to each module. Each communication link includes a data out line, a data in line and a clock line, where each clock line is derived from one clock source.