Patents by Inventor James McShane
James McShane has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220023275Abstract: An aqueous pharmaceutical formulation of a solubilizing agent with a pyridone compound that is useful as an inhibitor to non-NMDA receptors, particularly to the AMPA receptor is disclosed herein. In some embodiments the pyridone compound is supersaturated in aqueous solution at pH between 6 and 8. The formulations are particularly useful as intravenous injections.Type: ApplicationFiled: December 16, 2019Publication date: January 27, 2022Applicant: Eisai R&D Management Co., Ltd.Inventors: Geoffrey S. HIRD, Ganesh S.P. BOMMAREDDY, Anjali JOSHI, Ph.D., James MCSHANE
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Patent number: 10214227Abstract: A foot lever assist mechanism permits transport dollies to be more heavily loaded, saving the worker additional trips to deliver the entire supply. The lever assist may be configured to move from dolly to dolly, being secured by a pair of thumb screws or welded in place, secured to the axle. An auxiliary feature of this lever assist is the provision of a telescoping ladder-like extender and an extra long base which maximizes the advantage this foot lever assist mechanism provides.Type: GrantFiled: August 9, 2017Date of Patent: February 26, 2019Inventors: Nick Taylor, Rick Scriven, James McShane
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Patent number: 8596698Abstract: A two-piece telescoping handle mounts on the threaded ends of a tilt-tube of an outboard motor, moving from a first unobtrusive, retracted position to an extended position where the handle can be readily gripped to remove/carry the outboard motor, as needed.Type: GrantFiled: December 28, 2011Date of Patent: December 3, 2013Inventors: Rick Scriven, James McShane
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Publication number: 20130205807Abstract: A beverage cooler has a low voltage DC supply (311) usable by the controller ancillaries, such as lighting (318), the DC supply also providing the supply voltage to a microprocessor (313) which electronically commutates at least one of the motors (305, 306, 307) associated with beverage cooling to provide a required speed or loading. The microprocessor also responds to and controls the cooler ancillaries, such as lighting, temperature and status reporting thereby allowing a reduced component count.Type: ApplicationFiled: March 3, 2011Publication date: August 15, 2013Applicant: WELLINGTON DRIVE TECHNOLOGIES LIMITEDInventors: David James Mcshane, David James Howell, Ross Martin Green
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Patent number: 7989432Abstract: The present invention provides micelles, solutions comprising micelles, methods for preparing micelles, and methods for delivering micelles to patients. The micelles have fixed, preselected hydrodynamic diameters and are formed from basic or acidic amphiphilic compounds.Type: GrantFiled: June 19, 2008Date of Patent: August 2, 2011Assignee: Eisai R&D Management Co., Ltd.Inventors: James McShane, Tori Arens, Kazuhiro Kaneko, Tomohiro Watanabe, Kazuhide Ashizawa
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Publication number: 20090136564Abstract: The present invention provides micelles, solutions comprising micelles, methods for preparing micelles, and methods for delivering micelles to patients. The micelles have fixed, preselected hydrodynamic diameters and are formed from basic or acidic amphiphilic compounds.Type: ApplicationFiled: June 19, 2008Publication date: May 28, 2009Applicant: EISAI R&D MANAGEMENT CO., LTD.Inventors: James McShane, Tori Arens, Kazuhiro Kaneko, Tomohiro Watanabe, Kazuhide Ashizawa
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Patent number: 7390793Abstract: The present invention provides micelles, solutions comprising micelles, methods for preparing micelles, and methods for delivering micelles to patients. The micelles have fixed, preselected hydrodynamic diameters and are formed from basic or acidic amphiphilic compounds.Type: GrantFiled: April 15, 2005Date of Patent: June 24, 2008Assignee: Eisai Co., Ltd.Inventors: James McShane, Tori Arens, Kazuhiro Kaneko, Tomohiro Watanabe, Kazuhide Ashizawa
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Publication number: 20080095786Abstract: The invention provides pharmaceutical compositions for preventing and treating endotoxin-related diseases and conditions, as well as methods for making and using such compositions.Type: ApplicationFiled: March 5, 2004Publication date: April 24, 2008Inventor: James McShane
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Publication number: 20070276008Abstract: The present invention provides pharmaceutical formulations suitable for intravenous injection comprising a lyophilized anti-ulcerative agent reconstituted in isotonic solutions suitable for intravenous administration, such as 5% dextrose or 0.9% sodium chloride. The solutions are brought to a pH of between about 9 and about 12, preferably between about pH 10 and 11, by a glycine-sodium hydroxide buffer. Such formulations are chemically and physically stable, and do not significantly change color, for at least between about 6 and about 12 hours at room temperature, and are stable to color change for from between about 24 and 48 hours if kept at 5° C.Type: ApplicationFiled: February 6, 2007Publication date: November 29, 2007Applicant: Eisai Company LimitedInventors: James McShane, Ray Wood, Sumio Watanabe, Kiyoshi Iwamoto, Katsumi Onai
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Patent number: 7230014Abstract: The present invention provides pharmaceutical formulations suitable for intravenous injection comprising a lyophilized anti-ulcerative agent reconstituted in isotonic solutions suitable for intravenous administration, such as 5% dextrose or 0.9% sodium chloride. The solutions are brought to a pH of between about 9 and about 12, preferably between about pH 10 and 11, by a glycine-sodium hydroxide buffer. Such formulations are chemically and physically stable, and do not significantly change color, for at least between about 6 and about 12 hours at room temperature, and are stable to color change for from between about 24 and 48 hours if kept at 5° C.Type: GrantFiled: April 14, 2000Date of Patent: June 12, 2007Assignee: Eisai Co., Ltd.Inventors: James McShane, Ray Wood, Sumio Watanabe, Kiyoshi Iwamoto, Katsumi Onai
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Publication number: 20060222655Abstract: The invention provides pharmaceutical compositions for preventing and treating endotoxin-related diseases and conditions, as well as methods for making and using such compositions.Type: ApplicationFiled: March 5, 2004Publication date: October 5, 2006Inventor: James McShane
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Publication number: 20050181039Abstract: The present invention provides micelles, solutions comprising micelles, methods for preparing micelles, and methods for delivering micelles to patients. The micelles have fixed, preselected hydrodynamic diameters and are formed from basic or acidic amphiphilic compounds.Type: ApplicationFiled: April 15, 2005Publication date: August 18, 2005Applicant: Eisai Co., Ltd.Inventors: James McShane, Tori Arens, Kazuhiro Kaneko, Tomohiro Watanabe, Kazuhide Ashizawa
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Patent number: 6906042Abstract: The invention provides micelles, pharmaceutical formulations comprising micells, solutions comprising micells, methods for preparing micells, methods for delivering micells to patients, and methods for treating sepsis, endotoxemia, septic shock and systemic inflamatory response syndrome in patients by adiministering micelles. The micelles comprises compounds of Forumala (A): wherein the substituents are as defined herein.Type: GrantFiled: February 20, 2001Date of Patent: June 14, 2005Assignee: Eisai Co., Ltd.Inventors: James McShane, Tori Arens, Kazuhiro Kaneko, Tomohiro Watanabe, Kazuhide Ashizawa
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Publication number: 20030216331Abstract: The present invention provides micelles, solutions comprising micelles, methods for preparing micelles, and methods for delivering micelles to patients. The micelles have fixed, preselected hydrodynamic diameters and are formed from basic or acidic amphiphilic compounds.Type: ApplicationFiled: October 3, 2002Publication date: November 20, 2003Inventors: James McShane, Tori Arens, Kazuhiro Kaneko, Tomohiro Watanabe, Kazuhide Ashizawa
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Publication number: 20020177611Abstract: The present invention provides pharmaceutical formulations suitable for intravenous injection comprising a lyophilized anti-ulcerative agent reconstituted in isotonic solutions suitable for intravenous administration, such as 5% dextrose or 0.9% sodium chloride. The solutions are brought to a pH of between about 9 and about 12, preferably between about pH 10 and 11, by a glycine-sodium hydroxide buffer. Such formulations are chemically and physically stable, and do not significantly change color, for at least between about 6 and about 12 hours at room temperature, and are stable to color change for from between about 24 and 48 hours if kept at 5° C.Type: ApplicationFiled: May 3, 2002Publication date: November 28, 2002Inventors: James McShane, Ray Wood, Sumio Watanabe, Kiyoshi Iwamoto, Katsumi Onai
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Patent number: 6074630Abstract: A delivery system for sunscreen products that applies a dry, waterproof sunscreen composition to the skin. The delivery system for suncare products of the present invention is designed to apply only the required amount of sunscreen composition to the skin without excess. The sunscreen composition is applied to an article such as paper, nonwoven cloth or porous plastic which is subsequently rubbed onto the skin. Alternatively, the sunscreen may take the form of a wafer or a bar with or without a support article. A delivery system for suncare products which include dihydroxyacetone in order to produce a semi-permanent color that gives the appearance of a natural suntan is described which utilizes the same self-leveling principle as the delivery system for suncare products containing sunscreen compositions.Type: GrantFiled: November 23, 1999Date of Patent: June 13, 2000Inventors: Richard L. Devillez, James McShane
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In-line drug delivery device for use with a standard IV administration set and a method for delivery
Patent number: 5547471Abstract: A receptacle (500) is provided for coupling an adaptor (10) having a vial (54) including a beneficial agent to an IV administration set (526). In an embodiment, the receptacle (500) includes an injection site (512) for receiving a cannula (26) from the adaptor (10). A resilient divider (516) separates the receptacle (500) into two sections defined by an upper fitment (508) and a lower fitment (510). A container (520) holding a solution is in fluid communication with the receptacle (500) via an inlet (502). A through bore (518) allows the solution from the container (520) to pass through the resilient divider (516) when the adaptor (10) is removed from the receptacle (500).Type: GrantFiled: November 22, 1993Date of Patent: August 20, 1996Assignee: Baxter International Inc.Inventors: Stacey S. Thompson, James McShane, Joseph Wong, Ray W. Wood -
Patent number: 5385547Abstract: A drug delivery device is provided for coupling a first container including a beneficial agent to a second member. In an embodiment, the device includes a substantially hollow member having a cannula mounted within a wall that divides the substantially hollow member into a first and second section. The first section includes means for receiving at least a portion of a first container. The substantially hollow member includes a wall that defines an exterior of the first section that is substantially flexible. A number of different cannula and flow path structures within the hollow member are possible pursuant to the present invention.Type: GrantFiled: November 19, 1992Date of Patent: January 31, 1995Assignee: Baxter International Inc.Inventors: Joseph Wong, Ray W. Wood, James McShane