Patents by Inventor James Mellor
James Mellor has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11350761Abstract: The present invention provides an inflatable panel (10) comprising an inflatable first part (12) having an internal compartment (13); an inflatable second part (14) having an internal compartment (15); and a third part (16) connecting the first part (12) to the second part (14) at a periphery of the first and second parts (12, 14). The first, second, and third parts (12, 14, 16) together define a sealed enclosure (18) therebetween. The inflatable panel (10) also includes means for evacuating air from the sealed enclosure (18), and said sealed enclosure is configured to increase thermal insulation between the first part (12) and the second part (14).Type: GrantFiled: September 10, 2018Date of Patent: June 7, 2022Inventor: Edward James Mellors
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Publication number: 20200345150Abstract: The present invention provides an inflatable panel (10) comprising an inflatable first part (12) having an internal compartment (13); an inflatable second part (14) having an internal compartment (15); and a third part (16) connecting the first part (12) to the second part (14) at a periphery of the first and second parts (12, 14). The first, second, and third parts (12, 14, 16) together define a sealed enclosure (18) therebetween. The inflatable panel (10) also includes means for evacuating air from the sealed enclosure (18), and said sealed enclosure is configured to increase thermal insulation between the first part (12) and the second part (14).Type: ApplicationFiled: September 10, 2018Publication date: November 5, 2020Inventor: EDWARD JAMES MELLORS
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Patent number: 7227017Abstract: A process for the synthesis of phosphorothioate oligonucleotides is provided which comprises assembling an oligonucleotide bound to a solid support in the presence of acetonitrile; prior to cleaving the oligonucleotide from the solid support removing the acetonitrile; and cleaving the oligonucleotide from the solid support. The process is particularly suited to the large scale synthesis of nucleotides. The acetonitrile may be removed from the solid support by one or both of drying and by washing with solvents. Preferred washing solvents comprise trialkylamines.Type: GrantFiled: June 5, 2003Date of Patent: June 5, 2007Assignee: Avecia LimitedInventors: Ben James Mellor, Donald Alfred Wellings, Mark Edward Douglas
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Publication number: 20050004644Abstract: Minimally invasive introducers and methods that can be used for rotationally securing devices within the human body. Introducers can include a distal element for releasably engaging a lead head controllable from a proximal control located outside of the body. An inner stem can extend between a proximal portion and a distal portion, and be pivotally and rotatably coupled to the distal lead engagement mechanism. An outer tube can be rotatably disposed over the inner stem and be flexibly coupled over the pivot to rotationally drive the distal element. A helical epicardial-myocardial lead electrode can be secured and oriented straight ahead and introduced through a port or small incision with the introducer in a straight configuration. The introducer can then be bent and rotated to screw the helical electrode into the heart.Type: ApplicationFiled: May 6, 2004Publication date: January 6, 2005Applicant: Enpath Medical, Inc.Inventors: Daniel Kelsch, James Mellor, Kenneth Rundle, Roger Fell, Scott Jahns, Dave Erickson, Vincent Fischer, Kent Anderson
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Patent number: 6768005Abstract: A process for the synthesis of phosphorothioate oligonucleotides is provided which comprises assembling an oligonucleotide bound to a solid support in the presence of acetonitrile; prior to cleaving the oligonucleotide from the solid support removing the acetonitrile; and cleaving the oligonucleotide from the solid support. The process is particularly suited to the large scale synthesis of nucleotides.Type: GrantFiled: December 20, 2000Date of Patent: July 27, 2004Assignee: Avecia LimitedInventors: Ben James Mellor, Donald Alfred Wellings, Mark Edward Douglas
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Publication number: 20030229221Abstract: A process for the synthesis of phosphorothioate oligonucleotides is provided which comprises assembling an oligonucleotide bound to a solid support in the presence of acetonitrile; prior to cleaving the oligonucleotide from the solid support removing the acetonitrile; and cleaving the oligonucleotide from the solid support. The process is particularly suited to the large scale synthesis of nucleotides. The acetonitrile may be removed from the solid support by one or both of drying and by washing with solvents. Preferred washing solvents comprise trialkylamines.Type: ApplicationFiled: June 5, 2003Publication date: December 11, 2003Applicant: AVECIA LIMITEDInventors: Ben James Mellor, Donald Alfred Wellings, Mark Edward Douglas
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Patent number: 6545188Abstract: A catalytic transfer hydrogenation process is provided. The catalyst employed in the process is a metal cyclopentadienyl complex which is coordinated to defined bidentate ligands. Preferred metals include rhodium, ruthenium and iridium. Preferred bidentate ligands are diamines and aminoalcohols, particularly those comprising chiral centers. The hydrogen donor is advantageously a secondary alcohol or a mixture of triethylamine and formic acid. The process can be employed to transfer hydrogenate ketones and imines, which are preferably prochiral. Catalysts for use in such a process are also provided.Type: GrantFiled: February 27, 2002Date of Patent: April 8, 2003Assignee: Avecia LimitedInventors: Andrew John Blacker, Ben James Mellor
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Publication number: 20020156282Abstract: A catalytic transfer hydrogenation process is provided. The catalyst employed in the process is a metal cyclopentadienyl complex which is coordinated to defined bidentate ligands. Preferred metals include rhodium, ruthenium and iridium. Preferred bidentate ligands are diamines and aminoalcohols, particularly those comprising chiral centers. The hydrogen donor is advantageously a secondary alcohol or a mixture of triethylamine and formic acid. The process can be employed to transfer hydrogenate ketones and imines, which are preferably prochiral. Catalysts for use in such a process are also provided.Type: ApplicationFiled: February 27, 2002Publication date: October 24, 2002Applicant: Avecia LimitedInventors: Andrew John Blacker, Ben James Mellor
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Publication number: 20020111479Abstract: A process for the synthesis of phosphorothioate oligonucleotides is provided which comprises assembling an oligonucleotide bound to a solid support in the presence of acetonitrile; prior to cleaving the oligonucleotide from the solid support removing the acetonitrile; and cleaving the oligonucleotide from the solid support. The process is particularly suited to the large scale synthesis of nucleotides.Type: ApplicationFiled: December 20, 2000Publication date: August 15, 2002Inventors: Ben James Mellor, Donald Alfred Wellings, Mark Edward Douglas
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Patent number: 6372931Abstract: A catalytic transfer hydrogenation process is provided. The catalyst employed in the process is a metal cyclopentadienyl complex which is coordinated to defined bidentate ligands. Preferred metals include rhodium, ruthenium and iridium. Preferred bidentate ligands are diamines and aminoalcohols, particularly those comprising chiral centers. The hydrogen donor is advantageously a secondary alcohol or a mixture of triethylamine and formic acid. The process can be employed to transfer hydrogenate ketones and imines, which are preferably prochiral. Catalysts for use in such a process are also provided.Type: GrantFiled: November 9, 1999Date of Patent: April 16, 2002Assignee: Avecia LimitedInventors: Andrew John Blacker, Ben James Mellor
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Patent number: 5710127Abstract: The present invention relates to a composition comprising exogenous human or animal IGF-I or IGF-II or both or effective analogs thereof comprising foodstuff for oral administration wherein the foodstuff is selected from the group consisting of artificial milk, natural milk and colostrum.Type: GrantFiled: March 7, 1996Date of Patent: January 20, 1998Assignee: Pharmacia & Upjohn AktiebolagInventors: Peter David Gluckman, David James Mellor