Abstract: Systems and methods disclosed herein provide advanced security and situational awareness solutions enabling, real-time intelligence and a rapid response capability for businesses, first responders and off-site personnel needing real-time information to plan short-, mid- and long-term responses to specific situations. Site sentinel systems and methods include a digital representation of a site, at least one detection sensor for monitoring the site, a sensor signature analyzer for processing data from each detection sensor to identify site abnormalities, and an analytics engine for generating output that synthesizes the digital representation with graphics positioning site abnormalities. The sentinel system may further include at least one drone for providing aerial reconnaissance of the site that is directed by a drone controller in response to identified site abnormalities.