Patents by Inventor James Michael Flanagan

James Michael Flanagan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11932854
    Abstract: The present invention relates to compounds, compositions, and methods for the study, diagnosis, and treatment of traits, diseases and conditions that respond to the modulation of gene expression and/or activity, and/or modulate a gene expression pathway. Specifically, the invention relates to double-stranded nucleic acid molecules including small nucleic acid molecules, such as short interfering nucleic acid (siNA) molecules that are capable of mediating or that mediate RNA interference (RNAi) against target gene expression.
    Type: Grant
    Filed: October 25, 2021
    Date of Patent: March 19, 2024
    Assignee: Sirna Therapeutics, Inc.
    Inventors: Mark Cancilla, James John Cunningham, William Michael Flanagan, Henry J. Haringsma, Denise M. Kenski, Matthew G. Stanton, Steven M. Stirdivant, Aarron T. Willingham
  • Patent number: 8838574
    Abstract: An index advice record engine generates and stores index advice records. An index advice policy mechanism allows a user to define an index advice policy that specifies criteria for autonomic index creation, modification and deletion. An autonomic index mechanism reads the index advice records, compares this information with the criteria in the user-defined index advice policies, and determines whether an index should be created, modified or deleted based on the information in the index advice records and the index advice policies. By automating the process of creating, modifying and deleting indexes according to user-defined policies, the preferred embodiments alleviate human users from most of the work of manually creating, modifying and deleting indexes.
    Type: Grant
    Filed: June 9, 2006
    Date of Patent: September 16, 2014
    Assignee: International Business Machines Corporation
    Inventors: Mark John Anderson, Robert Joseph Bestgen, James Michael Flanagan, Scott Forstie, Thomas James Schreiber
  • Patent number: 8838573
    Abstract: An index advice record engine generates and stores index advice records. An index advice policy mechanism allows a user to define an index advice policy that specifies criteria for autonomic index creation. An autonomic index creation mechanism reads the index advice records, compares this information with the criteria in the user-defined index advice policies, and determines whether an index should be created based on the information in the index advice records and the index advice policies. By automating the process of creating indexes according to user-defined policies, the preferred embodiments alleviate human users from most of the work of manually creating indexes.
    Type: Grant
    Filed: June 9, 2006
    Date of Patent: September 16, 2014
    Assignee: International Business Machines Corporation
    Inventors: Mark John Anderson, Robert Joseph Bestgen, James Michael Flanagan, Scott Forstie, Thomas James Schreiber
  • Patent number: 8706751
    Abstract: Embodiments of the invention provide a method, article of manufacture, and an apparatus used to provide an interface driven by database tables. The method includes receiving a query identifier associated with a database query. The query is executed to generate a set of query results, and a set of actions associated with the set of query result is also identified. The set of query results and the set of actions are provided to a client component of the database-driven interface.
    Type: Grant
    Filed: December 13, 2006
    Date of Patent: April 22, 2014
    Assignee: International Business Machines Corporation
    Inventors: Mark John Anderson, David Stanley Charron, James Michael Flanagan, Scott L. Forstie
  • Patent number: 8595212
    Abstract: An index advice record engine generates and stores index advice records. An index advice policy mechanism allows a user to define an index advice policy that specifies criteria for autonomic index creation, modification and deletion. An autonomic index mechanism reads the index advice records, compares this information with the criteria in the user-defined index advice policies, and determines whether an index should be created, modified or deleted based on the information in the index advice records and the index advice policies. By automating the process of creating, modifying and deleting indexes according to user-defined policies, the preferred embodiments alleviate human users from most of the work of manually creating, modifying and deleting indexes.
    Type: Grant
    Filed: August 15, 2008
    Date of Patent: November 26, 2013
    Assignee: International Business Machines Corporation
    Inventors: Mark John Anderson, Robert Joseph Bestgen, James Michael Flanagan, Scott Forstie, Thomas James Schreiber
  • Patent number: 8452756
    Abstract: A database query optimizer includes an access plan storage mechanism that stores execution detail corresponding to a query statement in an access plan cache. By storing execution detail in the access plan cache along with the query statement, the execution detail is available when needed to debug database problems, even after a problem occurs. The execution detail stored in the access plan cache may be mined and analyzed after-the-fact, producing a very powerful tool for debugging database problems. Snapshots of the execution detail may also be created by a user. In addition, the user may setup autonomic snapshots and comparisons so that a user may be alerted from a degradation in database performance between two snapshots.
    Type: Grant
    Filed: November 9, 2006
    Date of Patent: May 28, 2013
    Assignee: International Business Machines Corporation
    Inventors: Mark John Anderson, Robert Joseph Bestgen, Daniel E. Beuch, Curtis Neal Boger, James Michael Flanagan, Scott Forstie, Shantan Kethireddy, Thomas Owen McKinley, Michael Donald Pfeifer
  • Patent number: 8121988
    Abstract: An index advice record engine generates and stores index advice records. An index advice policy mechanism allows a user to define an index advice policy that specifies criteria for autonomic index creation, modification and deletion. An autonomic index mechanism reads the index advice records, compares this information with the criteria in the user-defined index advice policies, and determines whether an index should be created, modified or deleted based on the information in the index advice records and the index advice policies. By automating the process of creating, modifying and deleting indexes according to user-defined policies, the preferred embodiments alleviate human users from most of the work of manually creating, modifying and deleting indexes.
    Type: Grant
    Filed: August 19, 2008
    Date of Patent: February 21, 2012
    Assignee: International Business Machines Corporation
    Inventors: Mark John Anderson, Robert Joseph Bestgen, James Michael Flanagan, Scott Forstie, Thomas James Schreiber
  • Patent number: 7792849
    Abstract: A database graphical comparison tool allows comparing database items that include multiple database statements and graphically displaying the comparison results in a ranked list of database statements. The graphical comparison tool includes a graphical user interface that allows a user to easily configure the tool for both manual and automatic (or scheduled) comparisons. In addition, the user may specify one or more actions that may be autonomically performed when the comparison of database items meets predefined criteria. Database items that may be compared using the database graphical comparison tool include optimizer monitors and plan cache snapshots.
    Type: Grant
    Filed: October 11, 2006
    Date of Patent: September 7, 2010
    Assignee: International Business Machines Corporation
    Inventors: Mark John Anderson, Christopher Julius Brandt, David Stanley Charron, James Michael Flanagan, Scott Forstie
  • Patent number: 7743052
    Abstract: A database management system maintains a record of queries which can be executed against the database. For a given auxiliary database structure, an advisory function automatically reviews the query record and identifies those queries which might execute with greater efficiency using the auxiliary database structure, presenting analytical information to the user. Preferably, the auxiliary database structure is an index, and the information is used for determining whether to include the index in the database definition. Preferably, a query optimizer records potentially useful indexes when considering multiple alternative database optimizations, and this information is later retrieved to identify queries which would benefit from an index.
    Type: Grant
    Filed: February 14, 2006
    Date of Patent: June 22, 2010
    Assignee: International Business Machines Corporation
    Inventors: Robert Joseph Bestgen, James Michael Flanagan, Michael Donald Pfeifer
  • Publication number: 20090157742
    Abstract: A method and apparatus for tracking a plurality of database resource consumers is provided. A request is received from a job for a database resource of a plurality of resources. Based on the request, a database resource allocation amount for the job is updated. The database resource allocation amount specifies an amount of the database resource allocated to the job. It is determined whether the job is a primary consumer for the resource. A primary consumer is defined according to a consumption of the database resource relative to other database resource consumers. The determining is based on the database resource amount allocated to the job; and a respective database resource amount allocated to each of the plurality of database resource consumers. Upon determining that the job is one of the plurality of primary consumers, the job is added to a stored list identifying the primary consumers for the database resource.
    Type: Application
    Filed: December 12, 2007
    Publication date: June 18, 2009
    Inventors: Mark John Anderson, James Michael Flanagan, Scott Forstie
  • Publication number: 20080307009
    Abstract: An index advice record engine generates and stores index advice records. An index advice policy mechanism allows a user to define an index advice policy that specifies criteria for autonomic index creation, modification and deletion. An autonomic index mechanism reads the index advice records, compares this information with the criteria in the user-defined index advice policies, and determines whether an index should be created, modified or deleted based on the information in the index advice records and the index advice policies. By automating the process of creating, modifying and deleting indexes according to user-defined policies, the preferred embodiments alleviate human users from most of the work of manually creating, modifying and deleting indexes.
    Type: Application
    Filed: August 19, 2008
    Publication date: December 11, 2008
    Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Mark John Anderson, Robert Joseph Bestgen, James Michael Flanagan, Scott Forstie, Thomas James Schreiber
  • Publication number: 20080301196
    Abstract: An index advice record engine generates and stores index advice records. An index advice policy mechanism allows a user to define an index advice policy that specifies criteria for autonomic index creation, modification and deletion. An autonomic index mechanism reads the index advice records, compares this information with the criteria in the user-defined index advice policies, and determines whether an index should be created, modified or deleted based on the information in the index advice records and the index advice policies. By automating the process of creating, modifying and deleting indexes according to user-defined policies, the preferred embodiments alleviate human users from most of the work of manually creating, modifying and deleting indexes.
    Type: Application
    Filed: August 15, 2008
    Publication date: December 4, 2008
    Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Mark John Anderson, Robert Joseph Bestgen, James Michael Flanagan, Scott Forstie, Thomas James Schreiber
  • Publication number: 20080147602
    Abstract: Embodiments of the invention provide a method, article of manufacture, and an apparatus used to provide an interface driven by database tables. The method includes receiving a query identifier associated with a database query. The query is executed to generate a set of query results, and a set of actions associated with the set of query result is also identified. The set of query results and the set of actions are provided to a client component of the database-driven interface.
    Type: Application
    Filed: December 13, 2006
    Publication date: June 19, 2008
    Inventors: Mark John Anderson, David Stanley Charron, James Michael Flanagan, Scott L. Forstie
  • Publication number: 20080114718
    Abstract: A database query optimizer includes an access plan storage mechanism that stores execution detail corresponding to a query statement in an access plan cache. By storing execution detail in the access plan cache along with the query statement, the execution detail is available when needed to debug database problems, even after a problem occurs. The execution detail stored in the access plan cache may be mined and analyzed after-the-fact, producing a very powerful tool for debugging database problems. Snapshots of the execution detail may also be created by a user. In addition, the user may setup autonomic snapshots and comparisons so that a user may be alerted from a degradation in database performance between two snapshots.
    Type: Application
    Filed: November 9, 2006
    Publication date: May 15, 2008
    Inventors: Mark John Anderson, Robert Joseph Bestgen, Daniel E. Beuch, Curtis Neal Boger, James Michael Flanagan, Scott Forstie, Shantan Kethireddy, Thomas Owen McKinley, Michael Donald Pfeifer
  • Publication number: 20080091669
    Abstract: A database graphical comparison tool allows comparing database items that include multiple database statements and graphically displaying the comparison results in a ranked list of database statements. The graphical comparison tool includes a graphical user interface that allows a user to easily configure the tool for both manual and automatic (or scheduled) comparisons. In addition, the user may specify one or more actions that may be autonomically performed when the comparison of database items meets predefined criteria. Database items that may be compared using the database graphical comparison tool include optimizer monitors and plan cache snapshots.
    Type: Application
    Filed: October 11, 2006
    Publication date: April 17, 2008
    Inventors: Mark John Anderson, Christopher Julius Brandt, David Stanley Charron, James Michael Flanagan, Scott Forstie
  • Publication number: 20070294272
    Abstract: An index advice record engine generates and stores index advice records. An index advice policy mechanism allows a user to define an index advice policy that specifies criteria for autonomic index creation, modification and deletion. An autonomic index mechanism reads the index advice records, compares this information with the criteria in the user-defined index advice policies, and determines whether an index should be created, modified or deleted based on the information in the index advice records and the index advice policies. By automating the process of creating, modifying and deleting indexes according to user-defined policies, the preferred embodiments alleviate human users from most of the work of manually creating, modifying and deleting indexes.
    Type: Application
    Filed: June 9, 2006
    Publication date: December 20, 2007
    Inventors: Mark John Anderson, Robert Joseph Bestgen, James Michael Flanagan, Scott Forstie, Thomas James Schreiber
  • Publication number: 20070288489
    Abstract: An index advice record engine generates and stores index advice records. An index advice policy mechanism allows a user to define an index advice policy that specifies criteria for autonomic index creation, modification and deletion. An autonomic index mechanism reads the index advice records, compares this information with the criteria in the user-defined index advice policies, and determines whether an index should be created, modified or deleted based on the information in the index advice records and the index advice policies. By automating the process of creating, modifying and deleting indexes according to user-defined policies, the preferred embodiments alleviate human users from most of the work of manually creating, modifying and deleting indexes.
    Type: Application
    Filed: June 9, 2006
    Publication date: December 13, 2007
    Inventors: Mark John Anderson, Robert Joseph Bestgen, James Michael Flanagan, Scott Forstie, Thomas James Schreiber
  • Publication number: 20070288428
    Abstract: An index advice record engine generates and stores index advice records. An index advice policy mechanism allows a user to define an index advice policy that specifies criteria for autonomic index creation. An autonomic index creation mechanism reads the index advice records, compares this information with the criteria in the user-defined index advice policies, and determines whether an index should be created based on the information in the index advice records and the index advice policies. By automating the process of creating indexes according to user-defined policies, the preferred embodiments alleviate human users from most of the work of manually creating indexes.
    Type: Application
    Filed: June 9, 2006
    Publication date: December 13, 2007
    Inventors: Mark John Anderson, Robert Joseph Bestgen, James Michael Flanagan, Scott Forstie, Thomas James Schreiber