Patents by Inventor James Michael Siedlecki

James Michael Siedlecki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ß-1,6-glucan therapeutic antibody conjugates
    Patent number: 11865135
    Abstract: The present invention encompasses embodiments in which a therapeutic antibody is conjugated to ?-1,6-glucan oligomers. Thus, the present invention includes, among other things, compositions including a therapeutic antibody conjugated to one or more ?-1,6-glucan oligomers. The present invention further includes, among other things, methods of making and/or using such ?-1,6-glucan conjugates. In certain embodiments, a ?-1,6-glucan conjugate of the present invention is useful as a therapeutic or in a method of therapy.
    Type: Grant
    Filed: December 5, 2017
    Date of Patent: January 9, 2024
    Assignee: Innate Biotherapeutics, LLC
    Inventors: Gabriel Oscar Reznik, John James Kane, James Michael Siedlecki, Zuzana Dostalova, Isabelle Sansal-Castellano, Ifat Rubin-Bejerano, Hua Miao, Eric Steven Furfine
  • ß-1,6-GLUCAN THERAPEUTIC ANTIBODY CONJUGATES
    Publication number: 20200030360
    Abstract: The present invention encompasses embodiments in which a therapeutic antibody is conjugated to ?-1,6-glucan oligomers. Thus, the present invention includes, among other things, compositions including a therapeutic antibody conjugated to one or more ?-1,6-glucan oligomers. The present invention further includes, among other things, methods of making and/or using such ?-1,6-glucan conjugates. In certain embodiments, a ?-1,6-glucan conjugate of the present invention is useful as a therapeutic or in a method of therapy.
    Type: Application
    Filed: December 5, 2017
    Publication date: January 30, 2020
    Inventors: Gabriel Oscar Reznik, John James Kane, James Michael Siedlecki, Zuzana Dostalova, Isabelle Sansal-Castellano, Ifat Rubin-Bejerano, Hua Miao, Eric Steven Furfine
  • Immunomodulating beta-1,6-D-glucans
    Patent number: 10266609
    Abstract: This invention relates to modifications of ?-1,6-D-glucans, e.g., structures according to Formula (I), and the ability of these compositions to modulate an immune response.
    Type: Grant
    Filed: May 8, 2015
    Date of Patent: April 23, 2019
    Assignee: Innate Biotherapeutics, LLC
    Inventors: James Michael Siedlecki, Gabriel Oscar Reznik, John James Kane, Hua Miao, Arthur F. Kluge, Ifat Rubin-Bejerano
  • BETA-1,6-GLUCAN CETUXIMAB ANTIBODY CONJUGATES
    Publication number: 20180154014
    Abstract: The present invention encompasses embodiments in which cetuximab or a related cetuximab antibody is conjugated to ?-1,6-glucan oligomers. Thus, the present invention includes, among other things, compositions including cetuximab conjugated to one or more ?-1,6-glucan oligomers. The present invention further includes, among other things, methods of making and/or using such ?-1,6-glucan conjugates. In certain embodiments, a ?-1,6-glucan conjugate of the present invention is useful as a therapeutic or in a method of therapy.
    Type: Application
    Filed: June 1, 2016
    Publication date: June 7, 2018
    Inventors: Gabriel Oscar Reznik, John James Kane, James Michael Siedlecki, Zuzana Dostalova, Isabelle Sansal-Castellano, Ifat Rubin-Bejerano, Hua Miao
  • IMMUNOMODULATING BETA-1,6-D-GLUCANS
    Publication number: 20170081428
    Abstract: This invention relates to modifications of ?-1,6-D-glucans, e.g., structures according to Formula (I), and the ability of these compositions to modulate an immune response.
    Type: Application
    Filed: May 8, 2015
    Publication date: March 23, 2017
    Inventors: James Michael Siedlecki, Gabriel Oscar Reznik, John James Kane, Hua Miao, Arthur F. Kluge, Ifat Rubin-Bejerano