Abstract: Disclosed herein are glass pharmaceutical vials having sidewalls of reduced thickness. In embodiments, the glass pharmaceutical vial may include a glass body comprising a sidewall enclosing an interior volume. An outer diameter D of the glass body is equal to a diameter d1 of a glass vial of size X as defined by ISO 8362-1, wherein X is one of 2R, 3R, 4R, 6R, 8R, 10R, 15R, 20R, 25R, 30R, 50R, and 100R as defined by ISO 8362-1. However, the sidewall of the glass pharmaceutical vial comprises an average wall thickness Ti that is less than or equal to 0.85*s1, wherein s1 is a wall thickness of the glass vial of size X as defined by ISO 8362-1 and X is one of 2R, 3R, 4R, 6R, 8R, 10R, 15R, 20R, 25R, 30R, 50R, and 100R as defined by ISO 8362-1.

Abstract: Provided herein are methods for manufacturing of tumor reactive T cells that includes ex vivo enrichment of, and expansion of, cells secreting chemokine (C-X-C motif) ligand 13 (CXCL13); cells surface positive for C-X-C chemokine receptor type 5 (CXCR5); and/or one or more of CD39, PD-1 and TIGIT. Also provided are populations of T cells produced by methods described herein and pharmaceutical compositions thereof.

Abstract: The present concepts relate to lossless data compression techniques for reducing the size of a data structure. Certain data in the data structure that can be either recovered from another source or rebuilt from other available information may be removed from the data structure. To further reduce data size, the retained data in the data structure may be packed into a smaller-bit encoding data type. Additionally, to reduce the data size even more, the packed data may be zipped using a lossless data compression algorithm. To regain the original data structure, the process may be reversed. The zipped data may be unzipped using a lossless data decompression algorithm. The packed data may be unpacked into the original bit-sized data encoding. The removed data may be restored by either recovering it from another source or rebuilding it from other available information.

Abstract: Color and exposure matching for systems, such as a videoconferencing endpoint, that have overlapping camera fields of view. The geometric relationships between the overlapping cameras are used to determine correction processing. For each camera, histograms are developed for the overlapping cameras. A dynamic threshold is determined for each histogram. Using the dynamic threshold, peak detection is performed on each histogram. Using the geometric relationships, expected histogram relationships are determined. The actual histogram relationships are compared to the expected relationships, with further processing based on the correctness of the comparison. In some of the cases of further processing, peaks of the histograms are compared to find matching and non-matching peaks. Various ratios of pixels in the various peaks are used to determine needed changes to respective cameras.

Abstract: An apparatus for steam treating plant fibres is provided, the apparatus comprising: a steam manifold that is adapted to receive steam from a steam source and to distribute steam to a plurality of lances, the lances being configured to deliver steam into the interior volume of a batch of plant fibres; a temperature sensor for sensing a temperature of the batch of plant fibres, and a controller. The controller is configured to receive a signal from the temperature sensor, and to control the supply of steam to the lances to raise the temperature of the plant fibres to a target temperature. A method of steaming plant fibres is also provided.

Abstract: An apparatus for steam treating cannabis is provided, the apparatus comprising: a steam manifold (1) that is adapted to receive steam from a steam source and to distribute steam to a plurality of lances, the lances being configured to deliver steam into the interior volume of a batch of cannabis (10); a temperature sensor for sensing a temperature of the batch of cannabis, and a controller. The controller is configured to receive a signal from the temperature sensor (27), and to control the supply of steam to the lances to raise the temperature of the cannabis to a target temperature. A method of steaming cannabis is also provided.

Abstract: Color and exposure matching for systems, such as a videoconferencing endpoint, that have overlapping camera fields of view. The geometric relationships between the overlapping cameras are used to determine correction processing. For each camera, histograms are developed for the overlapping cameras. A dynamic threshold is determined for each histogram. Using the dynamic threshold, peak detection is performed on each histogram. Using the geometric relationships, expected histogram relationships are determined. The actual histogram relationships are compared to the expected relationships, with further processing based on the correctness of the comparison. In some of the cases of further processing, peaks of the histograms are compared to find matching and non-matching peaks. Various ratios of pixels in the various peaks are used to determine needed changes to respective cameras.

Abstract: Printing devices include a printer power supply, a printer processor connected to the printer power supply, printing components connected to the printer power supply and the printer processor, and a tablet interface device connected to the printer processor and the printer power supply. The tablet interface device includes a tablet processor, a USB connection electrically connected to the tablet processor and the printer power supply, and a touchscreen surface electrically connected to the tablet processor. The tablet processor is adapted to operate independently of the printer processor.

Abstract: Printing devices include a printer power supply, a printer processor connected to the printer power supply, printing components connected to the printer power supply and the printer processor, and a tablet interface device connected to the printer processor and the printer power supply. The tablet interface device includes a tablet processor, a USB connection electrically connected to the tablet processor and the printer power supply, and a touchscreen surface electrically connected to the tablet processor. The tablet processor is adapted to operate independently of the printer processor.

Abstract: The invention provides a water-in-oil emulsion for the preparation of a frozen confection, the emulsion comprising a weight ratio of water phase to oil phase of from 94:6 to 70:30 wherein: the oil phase comprises at least an edible oil and an emulsifier, the emulsifier having an average HLB of from 0.1 to 5; the water phase comprises at least water and one or more freezing point depressors; the emulsion comprises at least (W×A) wt % emulsifier by weight of the emulsion where: W is the proportion of the water phase in the emulsion expressed as the weight percentage of the total emulsion; and A is 0.0001; the emulsion comprises at most (O×0.

Abstract: An illustrated view of an exemplary float for fishing is presented. The float is useful for keeping a hook on a fishing line at a depth below a water line of a body of water. The float provides an easily visible, consistent depth for the hook on the fishing line. The float preferably has a shape of a bullet or a mortar. The float has a tail fin that is preferably orange in color. The tail fin is coupled to a casing, the casing preferably being gold in color. A tip that has a first portion and a second portion where the second portion may be a light. A first end of the tip is coupled to the casing and the second end is pointed and is coupled to an eyelet.

Abstract: The present invention relates to novel compounds or pharmaceutically acceptable salts thereof, corresponding pharmaceutical compositions and treatment methods or uses as antibacterials for bacterial infections.

Abstract: A markerless tracking device comprising a source configured to direct a beam on a plurality of beam paths, where each beam path illuminates a distinct region of an object; a sensor configured to receive beam reflected from each region in order to generate an image of each region; and a processor configured to generate a metric which indicates suitability of a beam trajectory, wherein the metric is generated by comparing images of selected regions, and wherein the beam trajectory is a path over which the beam is to be directed by the source during markerless tracking of the object.

Abstract: A compound of Formula (I), or a salt thereof, compositions comprising the compound, processes for its preparation and its use in therapy, for example in the treatment of parasitic diseases such as Chagas disease, Human African Trypanosomiasis (HAT), Animal African trypanosomiasis (AAT) and leishmaniasis, particularly visceral leishmaniasis (VL).

Abstract: The present invention relates to novel compounds or pharmaceutically acceptable salts thereof, corresponding pharmaceutical compositions and treatment methods or uses as antibacterials for bacterial infections.

Abstract: The present invention relates to novel compounds or pharmaceutically acceptable salts thereof, corresponding pharmaceutical compositions and treatment methods or uses as antibacterials for bacterial infections.

Abstract: System and method relates to measuring separation rate of water from water-in-crude oil emulsions at elevated temperature. The system includes an electrolytic interface (conductivity) cell comprising a plurality of capacitance/conductance probes disposed at different heights in a fluid stream disposed within the interface cell and an analyzer. Logic of the analyzer determines the separation rate based on signals received from the plurality of capacitance/conductance probes in the interface cell that are coupled to monitor the fluid stream. Methods for making and using the system are also disclosed.

Abstract: The compound 3,3,3-trifluoro-N-((1,4-trans)-4-((3-((S)-2-methylmorpholino)-IH-pyrazolo[3,4-d]pyrimidin-6-yl)amino)cyclohexyl)propane-1-sulfonamide having the Formula (I) or a salt thereof, its opposite enantiomer, compositions comprising the compound and its use in the treatment or prevention of leishmaniasis, particularly visceral leishmaniasis.