Abstract: The present concepts relate to lossless data compression techniques for reducing the size of a data structure. Certain data in the data structure that can be either recovered from another source or rebuilt from other available information may be removed from the data structure. To further reduce data size, the retained data in the data structure may be packed into a smaller-bit encoding data type. Additionally, to reduce the data size even more, the packed data may be zipped using a lossless data compression algorithm. To regain the original data structure, the process may be reversed. The zipped data may be unzipped using a lossless data decompression algorithm. The packed data may be unpacked into the original bit-sized data encoding. The removed data may be restored by either recovering it from another source or rebuilding it from other available information.

Abstract: Provided herein are methods for manufacturing of tumor reactive T cells that includes ex vivo enrichment of, and expansion of, cells secreting chemokine (C-X-C motif) ligand 13 (CXCL13); cells surface positive for C-X-C chemokine receptor type 5 (CXCR5); and/or one or more of CD39, PD-1 and TIGIT. Also provided are populations of T cells produced by methods described herein and pharmaceutical compositions thereof.

Abstract: Color and exposure matching for systems, such as a videoconferencing endpoint, that have overlapping camera fields of view. The geometric relationships between the overlapping cameras are used to determine correction processing. For each camera, histograms are developed for the overlapping cameras. A dynamic threshold is determined for each histogram. Using the dynamic threshold, peak detection is performed on each histogram. Using the geometric relationships, expected histogram relationships are determined. The actual histogram relationships are compared to the expected relationships, with further processing based on the correctness of the comparison. In some of the cases of further processing, peaks of the histograms are compared to find matching and non-matching peaks. Various ratios of pixels in the various peaks are used to determine needed changes to respective cameras.

Abstract: Color and exposure matching for systems, such as a videoconferencing endpoint, that have overlapping camera fields of view. The geometric relationships between the overlapping cameras are used to determine correction processing. For each camera, histograms are developed for the overlapping cameras. A dynamic threshold is determined for each histogram. Using the dynamic threshold, peak detection is performed on each histogram. Using the geometric relationships, expected histogram relationships are determined. The actual histogram relationships are compared to the expected relationships, with further processing based on the correctness of the comparison. In some of the cases of further processing, peaks of the histograms are compared to find matching and non-matching peaks. Various ratios of pixels in the various peaks are used to determine needed changes to respective cameras.

Abstract: Printing devices include a printer power supply, a printer processor connected to the printer power supply, printing components connected to the printer power supply and the printer processor, and a tablet interface device connected to the printer processor and the printer power supply. The tablet interface device includes a tablet processor, a USB connection electrically connected to the tablet processor and the printer power supply, and a touchscreen surface electrically connected to the tablet processor. The tablet processor is adapted to operate independently of the printer processor.

Abstract: Printing devices include a printer power supply, a printer processor connected to the printer power supply, printing components connected to the printer power supply and the printer processor, and a tablet interface device connected to the printer processor and the printer power supply. The tablet interface device includes a tablet processor, a USB connection electrically connected to the tablet processor and the printer power supply, and a touchscreen surface electrically connected to the tablet processor. The tablet processor is adapted to operate independently of the printer processor.

Abstract: An illustrated view of an exemplary float for fishing is presented. The float is useful for keeping a hook on a fishing line at a depth below a water line of a body of water. The float provides an easily visible, consistent depth for the hook on the fishing line. The float preferably has a shape of a bullet or a mortar. The float has a tail fin that is preferably orange in color. The tail fin is coupled to a casing, the casing preferably being gold in color. A tip that has a first portion and a second portion where the second portion may be a light. A first end of the tip is coupled to the casing and the second end is pointed and is coupled to an eyelet.

Abstract: The present invention relates to novel compounds or pharmaceutically acceptable salts thereof, corresponding pharmaceutical compositions and treatment methods or uses as antibacterials for bacterial infections.

Abstract: A markerless tracking device comprising a source configured to direct a beam on a plurality of beam paths, where each beam path illuminates a distinct region of an object; a sensor configured to receive beam reflected from each region in order to generate an image of each region; and a processor configured to generate a metric which indicates suitability of a beam trajectory, wherein the metric is generated by comparing images of selected regions, and wherein the beam trajectory is a path over which the beam is to be directed by the source during markerless tracking of the object.

Abstract: A compound of Formula (I), or a salt thereof, compositions comprising the compound, processes for its preparation and its use in therapy, for example in the treatment of parasitic diseases such as Chagas disease, Human African Trypanosomiasis (HAT), Animal African trypanosomiasis (AAT) and leishmaniasis, particularly visceral leishmaniasis (VL).

Abstract: The present invention relates to novel compounds or pharmaceutically acceptable salts thereof, corresponding pharmaceutical compositions and treatment methods or uses as antibacterials for bacterial infections.

Abstract: The present invention relates to novel compounds or pharmaceutically acceptable salts thereof, corresponding pharmaceutical compositions and treatment methods or uses as antibacterials for bacterial infections.

Abstract: The compound 3,3,3-trifluoro-N-((1,4-trans)-4-((3-((S)-2-methylmorpholino)-IH-pyrazolo[3,4-d]pyrimidin-6-yl)amino)cyclohexyl)propane-1-sulfonamide having the Formula (I) or a salt thereof, its opposite enantiomer, compositions comprising the compound and its use in the treatment or prevention of leishmaniasis, particularly visceral leishmaniasis.

Abstract: A compound of Formula (I), or a salt thereof, compositions comprising the compound, processes for its preparation and its use in therapy, for example in the treatment of parasitic diseases such as Chagas disease, Human African Trypanosomiasis (HAT) and leishmaniasis, particularly visceral leishmaniasis (VL).

Abstract: Systems, methods, and computer-readable media having computer-executable instructions embodied thereon that generate notifications that are delivered to translators who provide updates or translations that are included in localization resources for software applications are provided. Resources are stored on a computing device in a first database or a second database. The second database stores the content that is selected for modification or translation. The languages may be selected by one or more application developers or may be based on a geographic region associated with the content or the language currently associated with the content. One or more translators are identified based on matches to translator profiles included in the second database. The matching translators receive notifications, which inform the translator that updates or translations are requested. In turn, the translators may access the second database and provide the updates or translations.

Abstract: Systems, methods, and computer-readable media having computer-executable instructions embodied thereon that generate notifications that are delivered to translators who provide updates or translations that are included in localization resources for software applications are provided. Resources are stored on a computing device in a first database or a second database. The first database is configured to store software and has a first buffer that stores content selected for updating or translation and a second buffer for receiving updated content or translated content. The second database is configured to receive the content stored in the first buffer of the first database and to store profiles associated with translators. The second database provides a portal to authenticate the translator before allowing a translator to enter translations for the content stored in the second database. A notification component notifies translators of content that matches a language of the translators.

Abstract: A method can include operating a 3-axis accelerometer having two axes that define a plane and an axis perpendicular to the plane to provide acceleration values for the three axes; increasing a threshold responsive to an increase in magnitude of the acceleration value for the axis perpendicular to the plane or decreasing the threshold responsive to a decrease in magnitude of the acceleration value for the axis perpendicular to the plane; and orienting output to a display in either a portrait format or a landscape format based on comparing the acceleration values for the two axes that define the plane to the threshold.

Abstract: Systems, methods, and computer-readable media having computer-executable instructions embodied thereon that generate notifications that are delivered to translators who provide updates or translations that are included in localization resources for software applications are provided. Resources are stored on a cloud device in a development file or a public database. The public database stores the content that is selected for modification or translation. The languages may be selected by one or more application developers or may be based on a geographic region associated with the content or the language currently associated with the content. One or more translators are identified based on matches to translator profiles included in the public database. The matching translators receive notifications, which inform the translator that updates or translations are requested. In turn, the translators may access the public database and provide the updates or translations.