Abstract: Per-and polyfluoroalkyl substances (PFAS) are destroyed by oxidation in supercritical conditions. PFAS in water can be concentrated and prepared for destruction in a pretreatment phase. Following annihilation of the PFAS in supercritical conditions to levels below 5 parts per trillion (ppt), the water effluent can be used to recover heat, returned to sub-critical conditions, and then released back into the environment.

Abstract: The present invention relates generally to the fields of medicine, immunology, and cancer biology. More particularly, it concerns antibodies that target HSP70 and methods of their use. Provided herein are agents such as antibodies that target HSP70. Methods of treating cancer are provided, comprising administering to a patient in need thereof an effective amount of an HSP70-targeting agent such as an HSP70-specific antibody. The HSP70-specific antibody may enhance uptake of HSP70 by antigen presenting cells.

Abstract: Methods and materials for modulating low light and/or shade tolerance, and red light specific responses in plants are disclosed. For example, nucleic acids encoding low light and/or SD+EODFR-tolerance polypeptides are disclosed as well as methods for using such nucleic acids to transform plant cells. Also disclosed are plants having increased low light and/or SD+EODFR tolerance. In addition, methods and materials involved in increasing UV-B tolerance in plants and methods and materials involved in modulating biomass levels in plants are provided.

Abstract: A patient interface includes a frame assembly including connectors operatively attachable to headgear, a cushion assembly provided to the frame assembly and including a seal-forming structure structured to form a seal with the patient's nose and/or mouth, and an air delivery connector provided to the frame assembly and operatively connected to an air delivery tube for supplying the air at positive pressure along an air flow path. The cushion assembly is structured to releasably connect to the frame assembly independently of the air delivery connector. The air delivery connector is structured to releasably connect to the frame assembly independently of the cushion assembly.

Abstract: A media terminal includes two integrated currency devices, each device providing at least one feature/operation that is similar to or is the same as the other device. Two independent sessions to each device are made and presented to a transaction application of the terminal as a single aggregated session. When the transaction application issues a command through the single aggregated session, a decision is made that is transparent to the application as to which device should process the command on behalf of the application and the command is issued to the selected device over the corresponding independent session. Results or notifications provided by the selected device are aggregated and provided to the application over the single aggregated session. In an embodiment, the two integrated currency devices are different types of devices from one another.

Abstract: A system may include a boom assembly comprising a base member and an extension member. The system may include a hydraulic assembly comprising: a cylinder housing having an internal cavity, a piston positioned partially within the internal cavity and coupled to the extension member at a distal end of the piston, a piston head coupled to the piston at a proximal end of the piston, the piston head located within the cylinder, a pressure tube coupled to the cylinder and positioned within the internal cavity, a sensor element extending within the pressure tube, and a magnet coupled to the piston and proximate at least a portion of the sensor element.

Abstract: A remotely operated circuit interrupter includes: primary separable contacts coupled to an operating mechanism and a thermal-magnetic trip device structured to interrupt current from flowing to loads by opening the primary separable contacts during a fault event; and a fault current tolerant secondary switching mechanism including secondary separable contacts coupled to the primary separable contacts in series, Rogowski coils, a di/dt measurement circuit, a secondary solenoid driver, the Rogowski coils structured to continuously sense a rate (di/dt) of change of load current, the di/dt measurement circuit structured to receive a signal including the sensed di/dt, determine that the sensed di/dt has reached or exceeded a threshold current rate of change, and output a fault signal to the secondary solenoid driver based on the determination, the secondary solenoid driver structured to actuate the solenoids to fully open the secondary separable contacts using arc voltages of the primary and secondary contacts.

Abstract: The current disclosure provides binding polypeptides (e.g., antibodies), and effector moiety conjugates thereof (e.g., antibody-drug conjugates or ADCs), comprising a site-specifically engineered drug-glycan linkage within native or engineered glycans of the binding polypetpide. The current disclosure also provides nucleic acids encoding the antigen-binding polypeptides, recombinant expression vectors and host cells for making such antigen-binding polypeptides. Methods of using the antigen-binding polypeptides disclosed herein to treat disease are also provided.

Abstract: Systems and methods for managing cybersecurity for an entity are disclosed. An example method includes providing a content portal to a user configured to display a security risk profile via a generated GUI; receiving, via the generated GUI, a first input from the user comprising a selection of a component identified in the security risk profile and a response parameter; providing, via the generated GUI, parameters for a targeted scan of the selected component; receiving, via the generated GUI, a second input from the user comprising a selection of a confirmation of the parameters; identifying a vulnerability associated with a first property or a second property from device connectivity data based on the parameters; initiating the targeted scan of the selected component associated with the vulnerability; determining a result of the targeted scan; updating the security risk profile; and updating a multi-dimensional score based on the updated security risk profile.

Abstract: A nanosecond pulser system is disclosed. In some embodiments, the nanosecond pulser system may include a nanosecond pulser having a nanosecond pulser input; a plurality of switches coupled with the nanosecond pulser input; one or more transformers coupled with the plurality of switches; and an output coupled with the one or more transformers and providing a high voltage waveform with a amplitude greater than 2 kV and a frequency greater than 1 kHz based on the nanosecond pulser input. The nanosecond pulser system may also include a control module coupled with the nanosecond pulser input; and an control system coupled with the nanosecond pulser at a point between the transformer and the output, the control system providing waveform data regarding an high voltage waveform produced at the point between the transformer and the output.

Abstract: An unmanned vehicle (20) for relaying radio frequency signals in a tactical communications network is described. The unmanned vehicle comprises a processor (22) arranged to receive the location of a first asset (40a); select a relay site (30) from at least one relay site; and control the unmanned vehicle to move to the selected relay site, wherein at the selected relay site, communication between the first asset and the unmanned vehicle is enabled. The unmanned vehicle also comprises a receiver for receiving data from the first asset; and a transmitter for transmitting the data to a second asset (40b, 20, 10). A control unit (60) for an unmanned vehicle, a tactical communications network comprising a plurality of unmanned vehicles, and a method of relaying signals in a tactical communications network using an unmanned vehicle are all also described.

Abstract: A method and reactor for a hybrid thermo-electrochemical cycle using a layered reactive element is disclosed. The method includes heating the reactive element with a heat source, the reactive element having a metal oxide core that is redox-active, an outer layer, and an ion conductor layer between the core and the outer layer. The method includes increasing a chemical potential of oxygen in the core, driving O2? ions out as O2, the chemical potential increased through applying a first bias voltage between the core and the outer layer. The method includes exposing the reactive element to an input gas, and decreasing the chemical potential of oxygen in the core, driving oxygen from the input gas into the core leaving a gas product, the chemical potential decreased through applying a second bias voltage between the core and the outer layer. The first and second bias voltages have opposite polarity.

Abstract: An implant for shoulder arthroplasty includes a stem and optionally a head component or a cup component. The stem is sized and shaped to fit into an intramedullary canal of the humerus. The proximal portion of the stem has a concave taper and the distal portion of the stem has a taper. The distal taper includes an anterior-posterior taper and a medial-lateral taper. The shape of the stem loads the metaphysis of the humerus with a greater load than the load applied to the diaphysis of the humerus.

Abstract: A system includes a hot air vent extending about a heat source. The hot air vent is configured to produce an air flow by directing air heated by the heat source to rise upward along the hot air vent. The system further includes a wind turbine arranged at a top of the hot air vent configured to be operated by the heated air rising upward along the hot air vent.

Abstract: A suspension system (22) configured to minimize transmission of acoustic and vibrational energy in a device, comprising: (i) a rigid support (24): (ii) an operative element (16) positioned within the rigid support and comprising a drive frequency when the device is in operation; and (iii) a resilient element (26) engaging the rigid support and configured to create a resilient force against vibrations generated by the operative element in one or more degrees of freedom: wherein the natural frequency of a suspension mode in one or more of the degrees of freedom are tuned into a narrow resonant frequency range by the suspension, and wherein the resonant frequency is greater than the drive frequency.

Abstract: A media terminal includes two integrated currency devices, each device providing at least one feature/operation that is similar to or is the same as the other device. Two independent sessions to each device are made and presented to a transaction application of the terminal as a single aggregated session. When the transaction application issues a command through the single aggregated session, a decision is made that is transparent to the application as to which device should process the command on behalf of the application and the command is issued to the selected device over the corresponding independent session. Results or notifications provided by the selected device are aggregated and provided to the application over the single aggregated session. In an embodiment, the two integrated currency devices are different types of devices from one another.

Abstract: A glass container comprises a glass body comprising a first region under a compressive stress extending from a surface of the glass body to a depth of compression and a second region extending from the depth of compression into a thickness of the glass body, the second region being under a tensile stress. The glass container also includes a localized compressive stress region having a localized compressive stress extending from the surface to a localized depth of compression within the body. The localized depth of compression is greater than the depth of compression of the first region. The glass container also includes a crack re-direction region extending in a predetermined propagation direction, wherein the crack re-direction region possesses a higher tensile stress than the tensile stress in the second region in a sub-region of the crack re-direction region, the sub-region extending substantially perpendicular to the predetermined propagation direction.

Abstract: A system for storing materials in an earthen subterranean formation includes a wellbore extending from a terranean surface into the subterranean formation, the wellbore extending from an uphole end at the terranean surface to a longitudinally opposing downhole end, a casing string extending through the wellbore, wherein the casing string is cemented in place in the wellbore, a subterranean storage chamber formed in a salt deposit of the subterranean formation and fluidically connected to the wellbore, the storage chamber at least partially filled with brine and having a lateral width that exceeds a vertical height of the storage chamber, wellbore-transportable foreign material that is stored in the storage chamber.

Abstract: A refuse vehicle includes a chassis coupled a wheel, a motor configured to drive the wheel, a body assembly coupled to the chassis and defining a refuse compartment, a lift assembly, and a vehicle control system having a sensor integrated into the body assembly and a controller in communication with the lift assembly and the sensor. The controller includes a processor and at least one memory and is configured to receive sensor data from the sensor, the sensor data indicating a potential event, receive control data indicating a state the lift assembly, and compare the sensor data to the control data to determine if the potential event is a false event associated with the state of the lift assembly or an actual event.