Patents by Inventor James Miskin

James Miskin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Virus purification
    Patent number: 10273502
    Abstract: A process for producing a retroviral or lentiviral vector formulation comprising a filter-sterilisation step wherein the filter-sterilisation step is not the final step in the purification process.
    Type: Grant
    Filed: September 14, 2015
    Date of Patent: April 30, 2019
    Assignee: Oxford BioMedica (UK) Limited
    Inventors: Richard Truran, Robert Buckley, Pippa Radcliffe, James Miskin, Kyriacos Mitrophanous
  • Virus Purification
    Publication number: 20170175135
    Abstract: A process for producing a retroviral or lentiviral vector formulation comprising a filter-sterilisation step wherein the filter-sterilisation step is not the final step in the purification process.
    Type: Application
    Filed: September 14, 2015
    Publication date: June 22, 2017
    Applicant: OXFORD BIOMEDICA (UK) LIMITED
    Inventors: Richard Truran, Robert Buckley, Pippa Radcliffe, James Miskin, Kyriacos Mitrophanous
  • Virus Purification
    Publication number: 20170073702
    Abstract: A process for producing a retroviral or lentiviral vector formulation comprising a filter-sterilisation step wherein the filter-sterilisation step is not the final step in the purification process.
    Type: Application
    Filed: September 14, 2015
    Publication date: March 16, 2017
    Applicant: OXFORD BIOMEDICA (UK) LIMITED
    Inventors: Richard Truran, Robert Buckley, Pippa Radcliffe, James Miskin, Kyriacos Mitrophanous
  • Virus purification
    Patent number: 9169491
    Abstract: A process for producing a retroviral or lentiviral vector formulation comprising a filter-sterilization step wherein the filter-sterilization step is not the final step in the purification process.
    Type: Grant
    Filed: June 18, 2009
    Date of Patent: October 27, 2015
    Assignee: Oxford BioMedica (UK) Limited
    Inventors: Richard Truran, Robert Buckley, Pippa Radcliffe, James Miskin, Kyriacos Mitrophanous
  • VIRUS PURIFICATION
    Publication number: 20090325284
    Abstract: A process for producing a retroviral or lentiviral vector formulation comprising a filter-sterilisation step wherein the filter-sterilisation step is not the final step in the purification process.
    Type: Application
    Filed: June 18, 2009
    Publication date: December 31, 2009
    Inventors: Richard Truran, Robert Buckley, Pippa Radcliffe, James Miskin, Kyriacos Mitrophanous
  • Vector System
    Publication number: 20090111106
    Abstract: The present invention provides a vector system comprising a mutated post-transcriptional regulatory element. In particular, the present invention relates to a mutated WPRE sequence that can efficiently express nucleotides of interest in a retroviral vector system. The present invention also relates to methods of delivering and expressing nucleotides of interest to a target cell.
    Type: Application
    Filed: July 7, 2008
    Publication date: April 30, 2009
    Inventors: Kyri Mitrophanous, Jonathan Rohll, James Miskin, Susan Mary Kingsman
  • Vectors
    Publication number: 20090075370
    Abstract: The present invention relates to a polynucleotide comprising a nucleotide sequence encoding a retroviral gag protein, wherein the gag protein comprises a heterologous RNA binding domain capable of recognising a corresponding sequence in an RNA genome to facilitate packaging of the RNA genome into a retroviral vector particle.
    Type: Application
    Filed: June 13, 2008
    Publication date: March 19, 2009
    Inventors: Fraser Wilkes, James Miskin, Kyriacos Mitrophanous, Susan Kingsman
  • Viral Vectors
    Publication number: 20090017543
    Abstract: The present invention relates to an integration defective retroviral vector particle for gene therapy comprising a viral genome, wherein said vector particle is capable of infecting a mammalian target cell.
    Type: Application
    Filed: June 13, 2008
    Publication date: January 15, 2009
    Inventors: Fraser Wilkes, James Miskin, Kyriacos Mitrophanous, Susan Kingsman
  • Vector system
    Patent number: 7419829
    Abstract: The present invention provides a vector system comprising a mutated post-transcriptional regulatory element. In particular, the present invention relates to a mutated WPRE sequence that can efficiently express nucleotides of interest in a retroviral vector system. The present invention also relates to methods of delivering and expressing nucleotides of interest to a target cell.
    Type: Grant
    Filed: June 21, 2004
    Date of Patent: September 2, 2008
    Assignee: Oxford BioMedica (UK) Limited
    Inventors: Kyri Mitrophanous, Jonathan Rohll, James Miskin, Susan Marie Kingsman
  • Viral vector
    Publication number: 20050106559
    Abstract: Provided is a multicistronic retroviral vector genome having a first nucleic acid sequence upstream of at least one internal regulatory element, such that the level of genomic RNA available for packaging in the absence of rev, or a functional equivalent thereof, is increased.
    Type: Application
    Filed: May 7, 2004
    Publication date: May 19, 2005
    Inventors: Philippa Radcliffe, James Miskin, Fraser Wilkes, Kyriacos Mitrophanous, Susan Kingsman
  • Vector system
    Publication number: 20050002907
    Abstract: The present invention provides a vector system comprising a mutated post-transcriptional regulatory element. In particular, the present invention relates to a mutated WPRE sequence that can efficiently express nucleotides of interest in a retroviral vector system. The present invention also relates to methods of delivering and expressing nucleotides of interest to a target cell.
    Type: Application
    Filed: June 21, 2004
    Publication date: January 6, 2005
    Inventors: Kyri Mitrophanous, Jonathan Rohll, James Miskin, Susan Kingsman