Patents by Inventor James N. Plampin

James N. Plampin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for producing amidine sulfonic acid intermediates for guanidines
    Patent number: 4851094
    Abstract: An efficient synthesis of quanidines, e.g. of the formula (III), by oxidizing a thiourea, e.g. of the following formula (II): ##STR1## with H.sub.2 O.sub.2 and a molybdenum catalyst to yield an aminoiminomethane sulfonic acid which can then be reacted with an amine followed by optional transamination steps.
    Type: Grant
    Filed: July 20, 1987
    Date of Patent: July 25, 1989
    Assignee: McNeilab, Inc.
    Inventors: Cynthia A. Maryanoff, James N. Plampin, Robin C. Stanzione
  • Process for producing amidine sulfonic acid intermediates for guanidines
    Patent number: 4781866
    Abstract: An efficient synthesis of quanidines, e.g. of the formula (III), by oxidizing a thiourea, e.g. of the following formula (II): ##STR1## with H.sub.2 O.sub.2 and a molybdenum catalyst to yield an aminoiminomethane sulfonic acid which can then be reacted with an amine followed by optional transamination steps.
    Type: Grant
    Filed: November 24, 1986
    Date of Patent: November 1, 1988
    Assignee: McNeilab, Inc.
    Inventors: Cynthia A. Maryanoff, James N. Plampin, Robin C. Stanzione
  • Methane sulfonic acid derivatives
    Patent number: 4693850
    Abstract: Novel synthetic steps and intermediates leading to guanidines such as the anti-diabetic compound linogliride.
    Type: Grant
    Filed: November 26, 1986
    Date of Patent: September 15, 1987
    Assignee: McNeilab, Inc.
    Inventors: Cynthia A. Maryanoff, James N. Plampin, Robin C. Stanzione
  • Process for producing amidine sulfonic acids
    Patent number: 4656291
    Abstract: An efficient synthesis of quanidines, e.g. of the formula (III), by oxidizing a thiourea, e.g. of the following formula (II): ##STR1## with H.sub.2 O.sub.2 and a molybdenum catalyst to yield an aminoiminomethane sulfonic acid which can then be reacted with an amine followed by optional transamination steps.
    Type: Grant
    Filed: May 28, 1986
    Date of Patent: April 7, 1987
    Assignee: McNeilab, Inc.
    Inventors: Cynthia A. Maryanoff, James N. Plampin, Robin C. Stanzione
  • Process for producing guanidines such as linogliride
    Patent number: 4656270
    Abstract: Novel synthetic steps and intermediates leading to guanidines such as the anti-diabetic compound linogliride.
    Type: Grant
    Filed: March 15, 1985
    Date of Patent: April 7, 1987
    Assignee: McNeilab, Inc.
    Inventors: Cynthia A. Maryanoff, James N. Plampin, Robin C. Stanzione