Abstract: An assembly (10) for positioning sensors within a tire is provided that has first and second bead sensors (14,16), and first and second side-wall/shoulder sensors (18, 20). A first actuator (30) moves the sensors in a radial direction of the tire, and a second actuator (32) moves the first and second bead sensors in the axial direction of the tire. A third actuator (34) is present and moves the first and second bead sensors in the axial direction relative to the first and second sidewall/shoulder sensors. A fourth actuator (36) moves the first and second bead sensors in the axial direction relative to one another, and a fifth actuator (38) moves the first and second sidewall/shoulder sensors in the axial direction relative to one another.

Abstract: In some examples, an apparatus can include a syringe body including an electrical interface at a side surface of the syringe body, an interface at an end of the syringe body including an output at a distal surface of the syringe body, a print material particles reservoir located in the syringe body, and a structure to adapt a volume of the print material particles reservoir to move print material particles out of the print material particles reservoir through the output, where in response to the volume adapting structure moving from a first position to a second position, a signal is transmitted by the electrical interface.

Abstract: A pedal emulator (20, 100) is provided. The pedal emulator includes an emulator piston (28, 102) coupled to a damper (46, D1) that is contained within a housing (22, 104). The damper is surrounded by first (34, S1) and second (38, S2) springs that are carried by a lower spring seat (114), the lower spring seat being upwardly biased by a third spring (S3), for example a wave spring. The first and second springs and the third spring cooperate to provide a counter-force that is tailored to the desired feel of the pedal. First and second sensors measure travel (72, 74) and force in response to downward compression of the emulator piston, and the damper provides hysteresis upon return travel of the emulator piston.

Abstract: A pedal emulator (20, 100) is provided. The pedal emulator includes an emulator piston (28, 102) coupled to a damper (46, D1) that is contained within a housing (22, 104). The damper is surrounded by first (34, S1) and second (38, S2) springs that are carried by a lower spring seat (114), the lower spring seat being upwardly biased by a third spring (S3), for example a wave spring. The first and second springs and the third spring cooperate to provide a counter-force that is tailored to the desired feel of the pedal. First and second sensors measure travel (72,74) and force in response to downward compression of the emulator piston, and the damper provides hysteresis upon return travel of the emulator piston.

Abstract: A revetment system includes multiple layers to reinforce a surface exposed to possible high water flow. The revetment system includes both a cellular confinement layer and an articulated block layer. The cellular confinement layer is adapted to be placed on the ground surface to be protected. The block layer is mounted on top of that cellular confinement layer. Optional geosynthetic layers may be mounted under the cellular confinement layer and between the cellular confinement layer and block layers.

Abstract: A revetment system includes multiple layers to reinforce a surface exposed to possible high water flow. The revetment system includes both a cellular confinement layer and an articulated block layer. The cellular confinement layer is adapted to be placed on the ground surface to be protected. The block layer is mounted on top of that cellular confinement layer. Optional geosynthetic layers may be mounted under the cellular confinement layer and between the cellular confinement layer and block layers.

Abstract: The present invention relates, in general, to probes, methods, and kits used to determine the presence or absence of a microorganism in a sample. The probes, methods, and kits comprise at least one capture probe and/or at least one detector probe.

Abstract: A high-sensitivity, low-background immuno-amplification assay is provided, which offers a streamlined workflow suitable for high-throughput assays of clinically relevant samples, such as blood and other bodily fluids. The assay comprises the use of two proximity members that each comprise an analyte-specific binding component conjugated to an oligonucleotide. Binding an analyte brings the oligonucleotide moieties of the proximity members in sufficiently close contact that the oligonucleotides form an amplicon. The presence of the analyte then is detected through amplification of the amplicon and detection of the amplified nucleic acids. The sensitivity of the assay of the present invention is improved by preventing spurious or non-specific amplicon formation by proximity members that are not complexed with an analyte.

Abstract: A high-sensitivity, low-background immuno-amplification assay is provided, which offers a streamlined workflow suitable for high-throughput assays of clinically relevant samples, such as blood and other bodily fluids. The assay comprises the use of two proximity members that each comprise an analyte-specific binding component conjugated to an oligonucleotide. Binding an analyte brings the oligonucleotide moieties of the proximity members in sufficiently close contact that the oligonucleotides form an amplicon. The presence of the analyte then is detected through amplification of the amplicon and detection of the amplified nucleic acids. The sensitivity of the assay of the present invention is improved by preventing spurious or non-specific amplicon formation by proximity members that are not complexed with an analyte.

Abstract: A high-sensitivity, low-background immuno-amplification assay is provided, which offers a streamlined workflow suitable for high-throughput assays of clinically relevant samples, such as blood and other bodily fluids. The assay comprises the use of two proximity members that each comprise an analyte-specific binding component conjugated to an oligonucleotide. Binding an analyte brings the oligonucleotide moieties of the proximity members in sufficiently close contact that the oligonucleotides form an amplicon. The presence of the analyte then is detected through amplification of the amplicon and detection of the amplified nucleic acids. The sensitivity of the assay of the present invention is improved by preventing spurious or non-specific amplicon formation by proximity members that are not complexed with an analyte.

Abstract: The present invention relates, in general, to probes, methods, and kits used to determine the presence or absence of a microorganism in a sample. The probes, methods, and kits comprise at least one capture probe and/or at least one detector probe.

Abstract: The present invention relates, in general, to probes, methods, and kits used to determine the presence or absence of a microorganism in a sample. The probes, methods, and kits comprise at least one capture probe and/or at least one detector probe.

Abstract: Mass spectrometry techniques for determining the status of sepsis in an individual are provided. A biomarker profile resolved from a biological sample, taken from the individual, using a mass spectrometry technique is compared to a reference biomarker profile. A single such comparison classifies the individual as belonging to or not belonging to a reference population. The individual's biomarker profile and the reference biomarker profile comprise a plurality of ions each having a mass-to-charge ratio of about 100 Daltons to about 1000 Daltons. The plurality of ions can be detected by electrospray ionization mass spectrometry in positive mode. The comparison uses a decision rule, such as a classification tree, that determines the status of sepsis in the individual without requiring knowledge of the identity of the biomarkers in the biomarker profile from the individual and without requiring knowledge of the identity of the biomarkers in the reference biomarker profile.

Abstract: The present invention relates, in general, to probes, methods, and kits used to determine the presence or absence of a microorganism in a sample. The probes, methods, and kits comprise at least one capture probe and/or at least one detector probe.

Abstract: The invention employs an unlabeled signal primer comprising a 5? adapter sequence for detection of nucleic acid target sequences. The detection system further comprises a reporter probe, the 3? end of which hybridizes to the complement of the 5? adapter sequence of the signal primer to produce a 5? overhang, Polymerase is used to fill in the overhang and synthesize the complement of the 5? overhang of the reporter probe. Synthesis of the reporter probe complement is detected, either directly or indirectly, as an indication of the presence of the target.

Abstract: An improved method of controlling topographical variations when milling a cross-section of a structure, which can be used to reduce topographical variation on a cross-section of a write-head in order to improve the accuracy of metrology applications. Topographical variation is reduced by using a protective layer that comprises a material having mill rates at higher incidence angles that closely approximate the mill rates of the structure at those higher incidence angles. Topographical variation can be intentionally introduced by using a protective layer that comprises a material having mill rates at higher incidence angles that do not closely approximate the mill rates of the structure at those higher incidence angles.

Abstract: A high-sensitivity, low-background immuno-amplification assay is provided, which offers a streamlined workflow suitable for high-throughput assays of clinically relevant samples, such as blood and other bodily fluids. The assay comprises the use of two proximity members that each comprise an analyte-specific binding component conjugated to an oligonucleotide. Binding an analyte brings the oligonucleotide moieties of the proximity members in sufficiently close contact that the oligonucleotides form an amplicon. The presence of the analyte then is detected through amplification of the amplicon and detection of the amplified nucleic acids. The sensitivity of the assay of the present invention is improved by preventing spurious or non-specific amplicon formation by proximity members that are not complexed with an analyte. In one embodiment, target-independent amplicon formation is prevented by using hybridization blocker oligonucleotides that bind oligonucleotide moieties that are not hybridized to each other.