Patents by Inventor James Nataro

James Nataro has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8906662
    Abstract: Provided are compositions and methods for treating inflammation due to an immune response. Non-limiting example compositions include class-2 SPATE proteins that are capable of cleaving proteins involved in an inflammatory immune response in a patient. Example compositions include at least one mucin-cleaving class-2 SPATE protein. Further example compositions include protein involved in intestinal colonization (Pic). Non-limiting example methods include methods of decreasing inflammation in a patient having inflammation and methods of perturbing immune response in a patient having a disease or condition in which an active immune response is attributable to a cause of the disease or condition, by administering to the patient a composition including at least one class-2 SPATE protein capable of cleaving proteins involved in an inflammatory immune response.
    Type: Grant
    Filed: December 22, 2010
    Date of Patent: December 9, 2014
    Assignee: University of Maryland, Baltimore
    Inventors: James Nataro, Fernando Ruiz-Perez
  • Publication number: 20130017173
    Abstract: Provided are compositions and methods for treating inflammation due to an immune response. Non-limiting example compositions include class-2 SPATE proteins that are capable of cleaving proteins involved in an inflammatory immune response in a patient. Example compositions include at least one mucin-cleaving class-2 SPATE protein. Further example compositions include protein involved in intestinal colonization (Pic). Non-limiting example methods include methods of decreasing inflammation in a patient having inflammation and methods of perturbing immune response in a patient having a disease or condition in which an active immune response is attributable to a cause of the disease or condition, by administering to the patient a composition including at least one class-2 SPATE protein capable of cleaving proteins involved in an inflammatory immune response.
    Type: Application
    Filed: December 22, 2010
    Publication date: January 17, 2013
    Inventors: James Nataro, Fernando Ruiz-Perez
  • Patent number: 7504108
    Abstract: Novel proteins and their corresponding nucleotide sequences in enteroaggregative Escherichia coli (EAEC) are provided. In particular, Aap and the five gene cluster (aat) of the AA probe region of the pAA plasmid of EAEC 042 have been identified, sequenced, and further characterized. The use of these novel proteins and their corresponding nucleotide sequences for diagnosis, therapy, and prevention of EAEC infections is also provided.
    Type: Grant
    Filed: April 24, 2006
    Date of Patent: March 17, 2009
    Assignee: University of Maryland, Baltimore
    Inventor: James Nataro
  • Patent number: 7495091
    Abstract: Novel proteins and their corresponding nucleotide sequences in enteroaggregative Escherichia coli (EAEC) are provided. In particular, Aap and the five gene cluster (aat) of the AA probe region of the pAA plasmid of EAEC 042 have been identified, sequenced, and further characterized. The use of these novel proteins and their corresponding nucleotide sequences for diagnosis, therapy, and prevention of EAEC infections is also provided.
    Type: Grant
    Filed: April 24, 2006
    Date of Patent: February 24, 2009
    Assignee: University of Maryland, Baltimore
    Inventor: James Nataro
  • Patent number: 7491398
    Abstract: Novel proteins and their corresponding nucleotide sequences in enteroaggregative Escherichia coli (EAEC) are provided. In particular, Aap and the five gene cluster (aat) of the AA probe region of the pAA plasmid of EAEC 042 have been identified, sequenced, and further characterized. The use of these novel proteins and their corresponding nucleotide sequences for diagnosis, therapy, and prevention of EAEC infections is also provided.
    Type: Grant
    Filed: April 24, 2006
    Date of Patent: February 17, 2009
    Assignee: University of Maryland, Baltimore
    Inventor: James Nataro
  • Patent number: 7488814
    Abstract: Novel proteins and their corresponding nucleotide sequences in enteroaggregative Escherichia coli (EAEC) are provided. In particular, Aap and the five gene cluster (aat) of the AA probe region of the pAA plasmid of EAEC 042 have been identified, sequenced, and further characterized. The use of these novel proteins and their corresponding nucleotide sequences for diagnosis, therapy, and prevention of EAEC infections is also provided.
    Type: Grant
    Filed: April 24, 2006
    Date of Patent: February 10, 2009
    Assignee: University of Maryland, Baltimore
    Inventor: James Nataro
  • Patent number: 7291334
    Abstract: Novel proteins and their corresponding nucleotide sequences in enteroaggregative Escherichia coli (EAEC) are provided. In particular, Aap and the five gene cluster (aat) of the AA probe region of the pAA plasmid of EAEC 042 have been identified, sequenced, and further characterized. The use of these novel proteins and their corresponding nucleotide sequences for diagnosis, therapy, and prevention of EAEC infections is also provided.
    Type: Grant
    Filed: April 14, 2006
    Date of Patent: November 6, 2007
    Assignee: University of Maryland, Baltimore
    Inventor: James Nataro
  • Patent number: 7276240
    Abstract: Novel proteins and their corresponding nucleotide sequences in enteroaggregative Escherichia coli (EAEC) are provided. In particular, Aap and the five gene cluster (aat) of the AA probe region of the pAA plasmid of EAEC 042 have been identified, sequenced, and further characterized. The use of these novel proteins and their corresponding nucleotide sequences for diagnosis, therapy, and prevention of EAEC infections is also provided.
    Type: Grant
    Filed: April 14, 2006
    Date of Patent: October 2, 2007
    Assignee: University of Maryland, Baltimore
    Inventor: James Nataro
  • Patent number: 7141662
    Abstract: Novel proteins and their corresponding nucleotide sequences in enteroaggregative Escherichia coli (EAEC) are provided. In particular, Aap and the five gene cluster (aat) of the AA probe region of the pAA plasmid of EAEC 042 have been identified, sequenced, and further characterized. The use of these novel proteins and their corresponding nucleotide sequences for diagnosis, therapy, and prevention of EAEC infections is also provided.
    Type: Grant
    Filed: December 2, 2002
    Date of Patent: November 28, 2006
    Assignee: University of Maryland, Baltimore
    Inventor: James Nataro
  • Publication number: 20060182759
    Abstract: Novel proteins and their corresponding nucleotide sequences in enteroaggregative Escherichia coli (EAEC) are provided. In particular, Aap and the five gene cluster (aat) of the AA probe region of the pAA plasmid of EAEC 042 have been identified, sequenced, and further characterized. The use of these novel proteins and their corresponding nucleotide sequences for diagnosis, therapy, and prevention of EAEC infections is also provided.
    Type: Application
    Filed: April 24, 2006
    Publication date: August 17, 2006
    Inventor: James Nataro
  • Publication number: 20060182757
    Abstract: Novel proteins and their corresponding nucleotide sequences in enteroaggregative Escherichia coli (EAEC) are provided. In particular, Aap and the five gene cluster (aat) of the AA probe region of the pAA plasmid of EAEC 042 have been identified, sequenced, and further characterized. The use of these novel proteins and their corresponding nucleotide sequences for diagnosis, therapy, and prevention of EAEC infections is also provided.
    Type: Application
    Filed: April 24, 2006
    Publication date: August 17, 2006
    Inventor: James Nataro
  • Publication number: 20060182758
    Abstract: Novel proteins and their corresponding nucleotide sequences in enteroaggregative Escherichia coli (EAEC) are provided. In particular, Aap and the five gene cluster (aat) of the AA probe region of the pAA plasmid of EAEC 042 have been identified, sequenced, and further characterized. The use of these novel proteins and their corresponding nucleotide sequences for diagnosis, therapy, and prevention of EAEC infections is also provided.
    Type: Application
    Filed: April 24, 2006
    Publication date: August 17, 2006
    Inventor: James Nataro
  • Patent number: 7090850
    Abstract: Novel proteins and their corresponding nucleotide sequences in enteroaggregative Escherichia coli (EAEC) are provided. In particular, Aap and the five gene cluster (aat) of the AA probe region of the pAA plasmid of EAEC 042 have been identified, sequenced, and further characterized. The use of these novel proteins and their corresponding nucleotide sequences for diagnosis, therapy, and prevention of EAEC infections is also provided.
    Type: Grant
    Filed: May 18, 2004
    Date of Patent: August 15, 2006
    Assignee: University of Maryland
    Inventor: James Nataro
  • Publication number: 20060177466
    Abstract: Novel proteins and their corresponding nucleotide sequences in enteroaggregative Escherichia coli (EAEC) are provided. In particular, Aap and the five gene cluster (aat) of the AA probe region of the pAA plasmid of EAEC 042 have been identified, sequenced, and further characterized. The use of these novel proteins and their corresponding nucleotide sequences for diagnosis, therapy, and prevention of EAEC infections is also provided.
    Type: Application
    Filed: April 24, 2006
    Publication date: August 10, 2006
    Inventor: James Nataro
  • Patent number: 7087230
    Abstract: Novel proteins and their corresponding nucleotide sequences in enteroaggregative Escherichia coli (EAEC) are provided. In particular, Aap and the five gene cluster (aat) of the AA probe region of the pAA plasmid of EAEC 042 have been identified, sequenced, and further characterized. The use of these novel proteins and their corresponding nucleotide sequences for diagnosis, therapy, and prevention of EAEC infections is also provided.
    Type: Grant
    Filed: May 18, 2004
    Date of Patent: August 8, 2006
    Assignee: University Of Maryland
    Inventor: James Nataro
  • Patent number: 7087741
    Abstract: Novel proteins and their corresponding nucleotide sequences in enteroaggregative Escherichia coli (EAEC) are provided. In particular, Aap and the five gene cluster (aat) of the AA probe region of the pAA plasmid of EAEC 042 have been identified, sequenced, and further characterized. The use of these novel proteins and their corresponding nucleotide sequences for diagnosis, therapy, and prevention of EAEC infections is also provided.
    Type: Grant
    Filed: May 18, 2004
    Date of Patent: August 8, 2006
    Assignee: University of Maryland, Baltimore
    Inventor: James Nataro
  • Publication number: 20060172355
    Abstract: Novel proteins and their corresponding nucleotide sequences in enteroaggregative Escherichia coli (EAEC) are provided. In particular, Aap and the five gene cluster (aat) of the AA probe region of the pAA plasmid of EAEC 042 have been identified, sequenced, and further characterized. The use of these novel proteins and their corresponding nucleotide sequences for diagnosis, therapy, and prevention of EAEC infections is also provided.
    Type: Application
    Filed: April 14, 2006
    Publication date: August 3, 2006
    Inventor: James Nataro
  • Publication number: 20060172354
    Abstract: Novel proteins and their corresponding nucleotide sequences in enteroaggregative Escherichia coli (EAEC) are provided. In particular, Aap and the five gene cluster (aat) of the AA probe region of the pAA plasmid of EAEC 042 have been identified, sequenced, and further characterized. The use of these novel proteins and their corresponding nucleotide sequences for diagnosis, therapy, and prevention of EAEC infections is also provided.
    Type: Application
    Filed: April 14, 2006
    Publication date: August 3, 2006
    Inventor: James Nataro
  • Publication number: 20040259139
    Abstract: Novel proteins and their corresponding nucleotide sequences in enteroaggregative Escherichia coli (EAEC) are provided. In particular, Aap and the five gene cluster (aat) of the AA probe region of the pAA plasmid of EAEC 042 have been identified, sequenced, and further characterized. The use of these novel proteins and their corresponding nucleotide sequences for diagnosis, therapy, and prevention of EAEC infections is also provided.
    Type: Application
    Filed: May 18, 2004
    Publication date: December 23, 2004
    Applicant: UNIVERSITY OF MARYLAND, BALTIMORE
    Inventor: James Nataro
  • Publication number: 20040235116
    Abstract: Novel proteins and their corresponding nucleotide sequences in enteroaggregative Escherichia coli (EAEC) are provided. In particular, Aap and the five gene cluster (aat) of the AA probe region of the pAA plasmid of EAEC 042 have been identified, sequenced, and further characterized. The use of these novel proteins and their corresponding nucleotide sequences for diagnosis, therapy, and prevention of EAEC infections is also provided.
    Type: Application
    Filed: May 18, 2004
    Publication date: November 25, 2004
    Applicant: UNIVERSITY OF MARYLAND, BALTIMORE
    Inventor: James Nataro