Patents by Inventor James Neuberger

James Neuberger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Identification of a novel retrovirus associated with primary biliary cirrhosis and autoimmune disorders
    Patent number: 6468737
    Abstract: The present invention relates, first, to the discovery, identification, and characterization of novel nucleic acid molecules, that are associated with PBC, Sjögren's syndrome, scleroderma, SLE, autoimmune thyroiditis and various other connective tissue disorders. The novel nucleotide sequences of the present invention are retroviral in origin and are indicative of a PBC retrovirus which bears a strong correlation with PBC. The present invention is based, in part, on the Applicant's data which is the first evidence to suggest that PBC patient's tissue may harbor a transmissible agent. The association of a retroviral infectious agent with PBC was first demonstrated by Applicants in vitro by co-culture of periportal lymph nodes derived from patients at time of transplantation and healthy biliary epithelium cells.
    Type: Grant
    Filed: June 1, 2000
    Date of Patent: October 22, 2002
    Assignee: Alton Ochsner Medical Foundation
    Inventors: Andrew L. Mason, Lizhe Xu, James Neuberger