Patents by Inventor James Newhouse

James Newhouse has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • KRas G12D inhibitors
    Patent number: 11964989
    Abstract: Compounds that inhibit KRas G12D. In particular, compounds that inhibit the activity of KRas G12D, pharmaceutical compositions comprising the compounds and methods of use therefor, and in particular, methods of treating cancer. The compounds have a general structure represented by Formula (I): or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: July 20, 2022
    Date of Patent: April 23, 2024
    Assignees: Mirati Therapeutics, Inc., Array BioPharma Inc.
    Inventors: Xiaolun Wang, Aaron Craig Burns, James Gail Christensen, John Michael Ketcham, John David Lawson, Matthew Arnold Marx, Christopher Ronald Smith, Shelley Allen, James F. Blake, Mark Joseph Chicarelli, Joshua Ryan Dahlke, Donghua Dai, Jay Bradford Fell, John Peter Fischer, Macedonio J. Mejia, Brad Newhouse, Phong Nguyen, Jacob Matthew O'Leary, Spencer Pajk, Martha E. Rodriguez, Pavel Savechenkov, Tony P. Tang, Guy P.A. Vigers, Qian Zhao, Dean Russell Kahn, John Gaudino, Michael Christopher Hilton
  • HER2 MUTATION INHIBITORS
    Publication number: 20240124474
    Abstract: This invention relates to compounds of Formula (I): and enantiomers thereof, and to pharmaceutically acceptable salts of Formula (I) and said enantiomers, wherein L1, L2, R1, R2, R3 and n are as defined herein. The invention further relates to pharmaceutical compositions comprising such compounds and salts, and to methods and uses of such compounds, salts and compositions for the treatment of abnormal cell growth, including cancer, in a subject in need thereof.
    Type: Application
    Filed: November 1, 2023
    Publication date: April 18, 2024
    Applicant: Array BioPharma Inc.
    Inventors: Mark Laurence BOYS, Bryan Daniel ELLIS, John Joseph GAUDINO, Erik James HICKEN, Ellen Ruth LAIRD, Nicholas Charles LAZZARA, Bradley Jon NEWHOUSE, Spencer Phillip PAJK
  • POROUS METAL OXIDE MICROSPHERES
    Publication number: 20230102667
    Abstract: Porous metal oxide microspheres are prepared via a process comprising forming a liquid dispersion of polymer nanoparticles and a metal oxide; forming liquid droplets of the dispersion; drying the droplets to provide polymer template microspheres comprising polymer nanospheres; and removing the polymer nanospheres from the template microspheres to provide the porous metal oxide microspheres. The porous microspheres exhibit saturated colors and are suitable as colorants for a variety of end-uses.
    Type: Application
    Filed: November 30, 2022
    Publication date: March 30, 2023
    Inventors: Rupa Hiremath Darji, James Newhouse, Vinothan N. Manoharan, Victoria Hwang, Anna B. Stephenson
  • POROUS METAL OXIDE MICROSPHERES WITH VARYING PORE SIZES
    Publication number: 20230031067
    Abstract: Porous metal oxide microspheres are prepared via a process comprising forming a liquid solution or dispersion of polydisperse polymer nanoparticles and a metal oxide; forming liquid droplets from the solution or dispersion; drying the liquid droplets to provide polymer template microspheres comprising polymer nanospheres and metal oxide; and removing the polymer nanospheres from the template microspheres to provide the porous metal oxide microspheres. The porous microspheres exhibit saturated colors and are suitable as colorants for a variety of end-uses.
    Type: Application
    Filed: October 11, 2022
    Publication date: February 2, 2023
    Inventors: Rupa Hiremath Darji, James Newhouse, Vinothan N. Manoharan, Victoria Hwang, Anna B. Stephenson
  • Porous metal oxide microspheres
    Patent number: 11517871
    Abstract: Porous metal oxide microspheres are prepared via a process comprising forming a liquid dispersion of polymer nanoparticles and a metal oxide; forming liquid droplets of the dispersion; drying the droplets to provide polymer template microspheres comprising polymer nanospheres; and removing the polymer nanospheres from the template microspheres to provide the porous metal oxide microspheres. The porous microspheres exhibit saturated colors and are suitable as colorants for a variety of end-uses.
    Type: Grant
    Filed: March 12, 2021
    Date of Patent: December 6, 2022
    Assignees: President and Fellows of Harvard College, BASF SE
    Inventors: Rupa Hiremath Darji, James Newhouse, Vinothan N. Manoharan, Victoria Hwang, Anna B. Stephenson
  • Porous metal oxide microspheres with varying pore sizes
    Patent number: 11471849
    Abstract: Porous metal oxide microspheres are prepared via a process comprising forming a liquid solution or dispersion of polydisperse polymer nanoparticles and a metal oxide; forming liquid droplets from the solution or dispersion; drying the liquid droplets to provide polymer template microspheres comprising polymer nanospheres and metal oxide; and removing the polymer nanospheres from the template microspheres to provide the porous metal oxide microspheres. The porous microspheres exhibit saturated colors and are suitable as colorants for a variety of end-uses.
    Type: Grant
    Filed: March 12, 2021
    Date of Patent: October 18, 2022
    Assignees: President and Fellows of Harvard College, BASF SE
    Inventors: Rupa Hiremath Darji, James Newhouse, Vinothan N. Manoharan, Victoria Hwang, Anna B. Stephenson
  • Method of forming porous metal oxide microspheres using polydisperse polymer nanospheres
    Patent number: 11185835
    Abstract: Porous metal oxide microspheres are prepared via a process comprising forming a liquid solution or dispersion of polydisperse polymer nanoparticles and a metal oxide; forming liquid droplets from the solution or dispersion; drying the liquid droplets to provide polymer template microspheres comprising polymer nanospheres and metal oxide; and removing the polymer nanospheres from the template microspheres to provide the porous metal oxide microspheres. The porous microspheres exhibit saturated colors and are suitable as colorants for a variety of end-uses.
    Type: Grant
    Filed: September 10, 2018
    Date of Patent: November 30, 2021
    Assignees: BASF SE, PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventors: Rupa Hiremath Darji, James Newhouse, Vinothan N. Manoharan, Victoria Hwang, Anna B. Stephenson
  • Method of forming porous metal oxide microspheres
    Patent number: 11179694
    Abstract: Porous metal oxide microspheres are prepared via a process comprising forming a liquid dispersion of polymer nanoparticles and a metal oxide; forming liquid droplets of the dispersion; drying the droplets to provide polymer template microspheres comprising polymer nanospheres; and removing the polymer nanospheres from the template microspheres to provide the porous metal oxide microspheres. The porous microspheres exhibit saturated colors and are suitable as colorants for a variety of end-uses.
    Type: Grant
    Filed: September 10, 2018
    Date of Patent: November 23, 2021
    Assignees: BASF SE, PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventors: Rupa Hiremath Darji, James Newhouse, Vinothan N. Manoharan, Victoria Hwang, Anna B. Stephenson
  • POROUS METAL OXIDE MICROSPHERES WITH VARYING PORE SIZES
    Publication number: 20210220792
    Abstract: Porous metal oxide microspheres are prepared via a process comprising forming a liquid solution or dispersion of polydisperse polymer nanoparticles and a metal oxide; forming liquid droplets from the solution or dispersion; drying the liquid droplets to provide polymer template microspheres comprising polymer nanospheres and metal oxide; and removing the polymer nanospheres from the template microspheres to provide the porous metal oxide microspheres. The porous microspheres exhibit saturated colors and are suitable as colorants for a variety of end-uses.
    Type: Application
    Filed: March 12, 2021
    Publication date: July 22, 2021
    Inventors: Rupa Hiremath Darji, James Newhouse, Vinothan N. Manoharan, Victoria Hwang, Anna B. Stephenson
  • POROUS METAL OXIDE MICROSPHERES
    Publication number: 20210197161
    Abstract: Porous metal oxide microspheres are prepared via a process comprising forming a liquid dispersion of polymer nanoparticles and a metal oxide; forming liquid droplets of the dispersion; drying the droplets to provide polymer template microspheres comprising polymer nanospheres; and removing the polymer nanospheres from the template microspheres to provide the porous metal oxide microspheres. The porous microspheres exhibit saturated colors and are suitable as colorants for a variety of end-uses.
    Type: Application
    Filed: March 12, 2021
    Publication date: July 1, 2021
    Inventors: Rupa Hiremath Darji, James Newhouse, Vinothan N. Manoharan, Victoria Hwang, Anna B. Stephenson
  • Porous Metal Oxide Microspheres
    Publication number: 20190076809
    Abstract: Porous metal oxide microspheres are prepared via a process comprising forming a liquid dispersion of polymer nanoparticles and a metal oxide; forming liquid droplets of the dispersion; drying the droplets to provide polymer template microspheres comprising polymer nanospheres; and removing the polymer nanospheres from the template microspheres to provide the porous metal oxide microspheres. The porous microspheres exhibit saturated colors and are suitable as colorants for a variety of end-uses.
    Type: Application
    Filed: September 10, 2018
    Publication date: March 14, 2019
    Inventors: Rupa Hiremath Darji, James Newhouse, Vinothan N. Manoharan, Victoria Hwang, Anna B. Stephenson
  • Microspheres Comprising Polydisperse Polymer Nanospheres and Porous Metal Oxide Microspheres
    Publication number: 20190076810
    Abstract: Porous metal oxide microspheres are prepared via a process comprising forming a liquid solution or dispersion of polydisperse polymer nanoparticles and a metal oxide; forming liquid droplets from the solution or dispersion; drying the liquid droplets to provide polymer template microspheres comprising polymer nanospheres and metal oxide; and removing the polymer nanospheres from the template microspheres to provide the porous metal oxide microspheres. The porous microspheres exhibit saturated colors and are suitable as colorants for a variety of end-uses.
    Type: Application
    Filed: September 10, 2018
    Publication date: March 14, 2019
    Inventors: Rupa Hiremath Darji, James Newhouse, Vinothan N. Manoharan, Victoria Hwang, Anna B. Stephenson
  • Extendable mirror assembly for a vehicle
    Patent number: 9969333
    Abstract: An extendable mirror assembly configured to be coupled to a vehicle includes a drive assembly, a mirror moveable between a retracted position and an extended position, and a support arm including a first end opposite a second end. The second end of the support arm is coupled to the mirror and a flange is coupled to the first end of the support arm. A support body is coupled to the support arm by the flange and is configured to translate along an axis in response to actuation of the drive assembly to move the mirror between the retracted position and the extended position.
    Type: Grant
    Filed: January 26, 2017
    Date of Patent: May 15, 2018
    Assignee: DEERE & COMPANY
    Inventors: Jacob E. Ervin, Kevin T. McCulloch, Shawn M Bartz, James A. Newhouse
  • EXTENDABLE MIRROR ASSEMBLY FOR A VEHICLE
    Publication number: 20170327040
    Abstract: An extendable mirror assembly configured to be coupled to a vehicle includes a drive assembly, a mirror moveable between a retracted position and an extended position, and a support arm including a first end opposite a second end. The second end of the support arm is coupled to the mirror and a flange is coupled to the first end of the support arm. A support body is coupled to the support arm by the flange and is configured to translate along an axis in response to actuation of the drive assembly to move the mirror between the retracted position and the extended position.
    Type: Application
    Filed: January 26, 2017
    Publication date: November 16, 2017
    Inventors: Jacob E. Ervin, Kevin T. McCulloch, Shawn M. Bartz, James A. Newhouse
  • Task light
    Patent number: 8240862
    Abstract: A task light assembly comprises a light head comprising a shade with an illuminator mounted therein, a support configured to suspend the light head above a work area and an adaptor mounted to the support and adjustably receiving at least a portion of the light head for lateral movement of the light head lateral position with respect to the support. The light head can be configured to project an asymmetrical light pattern onto a desired location on a work area and the asymmetrical light pattern can have a maximum intensity located laterally beyond the light head lateral position.
    Type: Grant
    Filed: December 28, 2009
    Date of Patent: August 14, 2012
    Assignee: Thomas J. Newhouse-Design
    Inventor: Thomas James Newhouse
  • Stacking side chair
    Patent number: D488631
    Type: Grant
    Filed: April 23, 2003
    Date of Patent: April 20, 2004
    Inventor: Thomas James Newhouse
  • Folding conference/training table with bent steel tube leg
    Patent number: D490252
    Type: Grant
    Filed: April 1, 2003
    Date of Patent: May 25, 2004
    Inventor: Thomas James Newhouse
  • Office chair
    Patent number: D490621
    Type: Grant
    Filed: April 23, 2003
    Date of Patent: June 1, 2004
    Inventor: Thomas James Newhouse
  • Folding conference/training table with curved foot casting
    Patent number: D492505
    Type: Grant
    Filed: April 1, 2003
    Date of Patent: July 6, 2004
    Inventor: Thomas James Newhouse