Abstract: An apparatus includes a fixed assembly and a reciprocating assembly. The fixed assembly includes a hopper, a first gas manifold, and a dispensing chamber, and the reciprocating assembly includes a channel assembly defining a channel conduit, a shield plate vertically aligned therewith, and a second gas manifold. The reciprocating assembly may move, in relation to the fixed assembly, to a first position to enable the channel conduit to be filled with bulk compressible material from the hopper, a second position to enable compressible material to be pushed from the channel conduit to the dispensing conduit and to be compressed in the dispensing chamber according to a first gas directed through the channel conduit by the first gas manifold, and a third position to enable the compressed material to be pushed out of the dispensing conduit according to a second gas directed through the dispensing conduit by the second gas manifold.

Abstract: Aspects of the disclosure provide fuel receptacle and boom tip position and pose estimation for aerial refueling. A video frame is received and within the video frame, aircraft keypoints for an aircraft to be refueled are determined. Based on at least the aircraft keypoints, a position and pose of a fuel receptacle on the aircraft is determined. Within the video frame, a boom tip keypoint for a boom tip of an aerial refueling boom is also determined. Based on at least the boom tip keypoint, a position and pose of the boom tip is determined. Based on at least the position and pose of the fuel receptacle and the position and pose of the boom tip, the aerial refueling boom is controlled to engage the fuel receptacle. Some examples overlay projections of an aircraft model on displayed video for a human observer.

Abstract: Approaches are provided for a prediction model determining a prediction indicative of the authorized user being associated with at least one anomaly event. In one example, a computer system may receive data from different sources. For example, the system may receive data associated with use of one or more monitored units of an automated storage and retrieval location. The system may also receive request data associated with a request for execution of the monitored controlled unit by an authorized user to a target user. The prediction model of the system may utilize the received data to determine the prediction that the authorized user is associated with at least one anomaly event associated with a diversion of a monitored unit away from the target user. The system may then provide the prediction for presentation.

Abstract: An optical device coating assembly is provided. The optical device coating assembly includes a substrate support operable to retain an optical device substrate. The coating assembly further includes a first actuator connected to the substrate support. The first actuator is configured to rotate the substrate support. The coating assembly includes a holder configured to hold a coating applicator against an edge of the optical device substrate when the optical device substrate is rotated on the substrate support and a second actuator operable to apply a force on the holder in a direction towards the substrate support. The second actuator is a constant force actuator.

Abstract: In one embodiment, a diagnostic system includes an instrument coupled to a client device and having at least one sample processing bay. The diagnostic system has a software architecture including instrument software (ISW) associated with the instrument. The ISW receives an assay definition file (ADF) that has a control file and an assay analysis module (AAM) file. The processing bay prepares and senses the sample according to parameters in the OPUS file and then generates sensor scan data. The diagnostic system then analyzes the sensor scan data and prepares a report according to the AAM file.

Abstract: Some examples relate to optimizing energy efficiency associated with workspaces in a building. In one specific example, a system can execute a trained machine-learning model to generate a predicted activity pattern associated with a workspace in a building, the predicted activity pattern being a forecast of workspace activity associated with the workspace over a future time window. The system can, based on the predicted activity pattern, generate at least one control signal for at least one control system associated with the workspace. And the system can transmit the at least one control signal to the at least one control system, the at least one control system being configured to receive the at least one control signal and responsively adjust at least one environmental condition associated with the workspace from a first setting to a second setting.

Abstract: Some examples relate to optimizing energy efficiency associated with workspaces in a building. In one specific example, a system can receive a selected time from a user for reserving a workspace in a building, The system can determine a recommended workspace for the user at the selected time based on an energy efficiency strategy. The system can then transmit at least one control signal to at least one control system associated with the recommended workspace. The at least one control system can receive the at least one control signal and responsively adjust at least one environmental condition associated with the recommended workspace from a first setting to a second setting. The at least one control system can adjust the at least one environmental condition from the first setting to the second setting by the selected time or within a predefined timeframe after the selected time.

Abstract: A packaging substrate can include a first surface having a first mounting region of a first electronic module region and a second mounting region of a second electronic module region, the second electronic module region being adjacent to the first electronic module region. The packaging substrate can include a second opposing surface having a first electrical contacts region of the first electronic module region and a second electrical contacts region of the second electronic module region. A saw street region can extend between the first and second electronic module regions, and a saw street feature can be formed on the second opposing surface within at least a portion of the saw street region, the saw street feature comprising a solder mask layer over a metal layer and being spaced from the first and second electronic module regions.

Abstract: The disclosure relates to chemokine CXCR4 receptor modulators and uses related thereto. The receptor modulators can be formulated to form pharmaceutical compositions comprising the disclosed compounds or pharmaceutically acceptable salts or prodrugs thereof. The compositions may be used for managing CXCR4 related conditions, typically prevention or treatment of viral infections abnormal cellular proliferation, retinal degeneration, inflammatory diseases, or as an immunostimulant or immunosuppressant or for managing cancer and may be administered with another active ingredient such as an antiviral agent or chemotherapeutic agent.

Abstract: A composition is provided for removal of a target substance from a fluid stream. The composition may be used to remove polyfluorinated alkyl substances (PFAS) from water. The composition comprises a support material comprising an alumina; and a sorbent molecule that comprises a core polymer; wherein the core polymer is covalently linked to the support material; and wherein the sorbent molecule further comprises one or more covalently linked sorbent groups. Processes for removal of target substances such as PFAS are also provided.

Abstract: The present invention relates to compounds that inhibit KRas G12D. In particular, the present invention relates to compounds that inhibit the activity of KRas G12D, pharmaceutical compositions comprising the compounds and methods of use therefor.

Abstract: A method of forming a batch of porous adsorbent filaments may include providing a precursor mixture, forcing the precursor mixture at a fixed rate through an orifice and then through a multiplicity of perforations in a belt, where the belt moves across and in tight registry with said orifice to form a batch of precursor porous adsorbent filaments, and drying the batch of precursor porous adsorbent filaments to form the batch of porous adsorbent filaments. The batch of porous adsorbent filaments may have a moisture content of at least about 20 wt. %.

Abstract: Retrieval of material from vessel lumens can be improved by use of a distal element comprising an expandable mesh. a treatment device includes an elongated member having a proximal portion and a distal portion configured to be positioned within a blood vessel at a treatment site at or near a thrombus. A distal element comprising a plurality of woven filaments defining a shaft at a proximal portion and a body distal of the shaft is coupled to the distal portion of the elongated member via a connection assembly. In an expanded state, at least a portion of the distal element is configured to be in apposition with the blood vessel wall at the treatment site to anchor or stabilize the elongated member with respect to the blood vessel. The distal element can be electrically coupled to an extracorporeal current generator.

Abstract: Embodiments of the present invention are directed to a Content Delivery Network (CDN) for broadcasting data streams. The CDN allows a streamer to stream live (in realtime) on a network(s), such as the Internet, for a live audience to view and to interact with the live entertainment. Each of the broadcast clients send data streams to the CDN via an input node, wherein the CDN output a selected media stream to one or more selected viewing clients via the output node. The architecture of the CDN contains one or more System Racks. Each of the System Racks contains multiple media channels. In operation, the data stream of a broadcasting client is sent to the CDN and distributed into selected channels. The data streams in each of the selected channels are outputted to viewing clients of a corresponding type.

Abstract: A tubing is anchored in a boiler casing positioned in a borehole that extends into a magma reservoir. The tubing may include a notch that is secured to a tubing anchor receptacle of the boiler casing. The boiler casing may include a float shoe that helps to prevent or restrict the flow of magma from the magma reservoir into the boiler casing and tubing.

Abstract: A gear shift assembly for selecting a gear in a vehicle transmission that includes a multipiece clamping assembly for connecting the driver's gear selector lever. The clamping assembly has separate saddle and clamp components that are fastened together to encircle the selector lever and position the selector lever in the gear shift assembly.

Abstract: A system, apparatus and method are provided for processing articles. The system includes subsystems for synthesizing, pre-treating, conducting a vapor phase coating process and post-treating articles in the form of powders and solid or porous workpieces. The apparatus permits vapor phase synthesis, treatment and deposition processes to be performed with high efficiency and at high overall throughput. The methods include converting solids, liquids or gases into gaseous and solid streams that can be separated or exchanged with or without treatment and/or coating steps, and produce optimized composite articles for specific applications.

Abstract: A multi-phase voltage converter has a plurality of integrated circuits (ICs), and a controller. Each IC has a temperature report pin and a temperature sensing circuit, the controller has a temperature input pin connected to the temperature report pin of each of the plurality of ICs. The controller provides an acquiring command via the temperature input pin to all of the ICs. The acquiring command is capable of selecting one of the plurality of ICs to report an individual temperature.

Abstract: A multi-phase voltage converter has a plurality of integrated circuits (ICs), and a controller. Each IC has a power switch, a monitoring pin and a current sense pin. The power switch is controlled to convert an input voltage to an output voltage. The current sense pin is capable of providing a current sense signal representative of a current flowing through the power switch. The controller is capable of providing a clock signal via the monitoring pin, and provides a plurality of data signals via the current sense pin of the plurality of ICs. Each of the plurality of ICs is assigned an identification code based on the clock signal and one of the plurality of data signals.

Abstract: A multi-phase voltage converter has a plurality of integrated circuits (ICs), and a controller. Each IC has a control pin to receive a control signal, a monitoring pin and a temperature sensing circuit, the controller has a monitoring pin connected to the monitoring pin of each of the plurality of ICs to receive a monitoring signal. The temperature sensing circuit is connected to or disconnected from the monitoring pin of the corresponding one of the plurality of ICs in response to the control signal and the monitoring signal.