Patents by Inventor James Nicholls
James Nicholls has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12239092Abstract: A waste receptacle (4) for animal excreta, the waste receptacle comprising: a base and at least one sidewall upstanding from the base, the base and at least one sidewall cooperating to define a housing having an internal void, a periphery of said at least one sidewall remote from said base defining an opening to said void; a platform support (41) coupled to said at least one sidewall in the vicinity of said sidewall periphery; and a platform (11) supportable by said platform support to partly obstruct said opening, said platform comprising first (13) and second (15) platform parts that are pivotally coupled to one another, neighbouring peripheral walls of said first and second platform parts each comprising a recess (202, 204), the recess in the peripheral wall of said first platform part cooperating with the recess in the peripheral wall of said second platform part to define an access port (5) for enabling an animal to access the internal void of the housing via said access port, said neighbouring walls ofType: GrantFiled: November 27, 2020Date of Patent: March 4, 2025Assignee: HEBE STUDIO LTDInventors: Simon Nicholls, James Tuthill, Johannes Paul, William Windham
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Publication number: 20250042931Abstract: Described herein are compositions and methods for the treatment or prevention of ocular surface disorders including meibomian gland dysfunction, blepharitis, dry eye disease and other inflammatory and/or infectious diseases of the anterior surface of the eye(s). Said compositions and methods comprise keratolytic conjugates which demonstrate keratolytic activity, and anti-inflammatory or other desirable activities. Topical administration of said compositions to the eyelid margin or surrounding areas provides therapeutic benefit to patients suffering from ocular surface disorders.Type: ApplicationFiled: October 10, 2024Publication date: February 6, 2025Inventors: Ian HOLMES, Yair ALSTER, Hila BARASH, Charles BOSWORTH, Omer RAFAELI, Robert M. BURK, Marc GLEESON, Mark Richard STEWART, Jonathan DUNN, Alexander James NICHOLLS
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Patent number: 12207621Abstract: A first implementation provides a clamp (10; 110; 210; 310) for connecting a plurality of wire mesh panels together, the clamp comprising a base (14; 114; 214; 314), a cap (12; 112; 212; 312) releasably attachable to the base, and a plurality of arms (18, 118, 218, 318) provided between the base and the cap to define a plurality of channels (500) within the clamp; wherein each said channel is configured to accommodate a portion of a loop of a respective one of said plurality of panels to connect the panels together.Type: GrantFiled: October 1, 2020Date of Patent: January 28, 2025Assignee: HEBE STUDIO LTD.Inventors: James Tuthill, Simon Nicholls, Johannes Paul, William Windham
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Publication number: 20230377272Abstract: Improved methods for generating a virtual representation of an interior space such as a room are provided. Techniques for capturing and normalizing sets of points for polygon mesh generation that utilize augmented reality toolkits are also described. The improved methods comprise: techniques for generating a polygon mesh that incorporates a projecting extrusion; techniques for generating a polygon mesh that incorporates curved surfaces; and techniques for generating a polygon mesh in real-time.Type: ApplicationFiled: August 2, 2023Publication date: November 23, 2023Inventors: James Nicholl, Robert Lewis, Owen McConnell, Jonathan Achenbach
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Patent number: 11816799Abstract: Methods, computer systems and computer programs for generating a virtual representation of an interior space such as a room are provided. Techniques for capturing and normalizing sets of points for polygon mesh generation that utilize augmented reality toolkits are also described.Type: GrantFiled: March 26, 2021Date of Patent: November 14, 2023Assignee: Signaturize Holdings LtdInventors: Jonathan Sinclair, Robert Lewis, James Nicholl, Ciaran Harrigan
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Patent number: 11692556Abstract: A seal includes a mating ring that rotates relative to a carbon primary ring at a seal interface. A buffer gas is provided into the seal and passes from the back of the primary ring to the seal interface. The seal can be used as a separation seal or in combination with another seal.Type: GrantFiled: June 15, 2022Date of Patent: July 4, 2023Assignee: JOHN CRANE UK LIMITEDInventors: Inderpal Singh Sihra, Isaac Lopez Higuera, Aidan James Nicholls
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Patent number: 11506217Abstract: A seal includes a mating ring that rotates relative to a porous carbon primary ring at a seal interface. A buffer gas is provided into the seal and passes from the back of the primary ring to the seal interface. The seal can be used as a separation seal or in combination with another seal.Type: GrantFiled: January 20, 2021Date of Patent: November 22, 2022Assignee: JOHN CRANE UK LIMITEDInventors: Inderpal Singh Sihra, Isaac Lopez Higuera, Aidaan James Nicholls
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Publication number: 20220352775Abstract: A coil structure for an electromagnetic device comprising a conductor configured to provide a coil comprising one or more coil turns around a magnetic core to induce a magnetic flux in the magnetic core when in use. The conductor comprises one or more a first parts comprising a plurality of sub-conductors in parallel, and one or more second parts coupled in series with the first part(s), wherein the or each second part comprises a single sub-conductor or a lesser number of sub-conductors in parallel.Type: ApplicationFiled: April 28, 2022Publication date: November 3, 2022Applicant: Technelec LtdInventors: Richard POLLOCK, James NICHOLLS, Peter DACKUS, Abigail CUMMING
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Publication number: 20220332749Abstract: Described herein are compositions and methods for the treatment or prevention of ocular surface disorders including meibomian gland dysfunction, blepharitis, dry eye disease and other inflammatory and/or infectious diseases of the anterior surface of the eye(s). Said compositions and methods comprise keratolytic conjugates which demonstrate keratolytic activity, and anti-inflammatory or other desirable activities. Topical administration of said compositions to the eyelid margin or surrounding areas provides therapeutic benefit to patients suffering from ocular surface disorders.Type: ApplicationFiled: June 15, 2022Publication date: October 20, 2022Inventors: Ian HOLMES, Yair ALSTER, Hila EPSTEIN-BARASH, Charles BOSWORTH, Omer RAFAELI, Robert M. BURK, Marc GLEESON, Mark Richard STEWART, Jonathan DUNN, Alexander James NICHOLLS
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Publication number: 20220332748Abstract: Described herein are compositions and methods for the treatment or prevention of ocular surface disorders including meibomian gland dysfunction, blepharitis, dry eye disease and other inflammatory and/or infectious diseases of the anterior surface of the eye(s). Said compositions and methods comprise keratolytic conjugates which demonstrate keratolytic activity, and anti-inflammatory or other desirable activities. Topical administration of said compositions to the eyelid margin or surrounding areas provides therapeutic benefit to patients suffering from ocular surface disorders.Type: ApplicationFiled: April 5, 2021Publication date: October 20, 2022Inventors: Ian HOLMES, Yair ALSTER, Hila BARASH, Charles BOSWORTH, Omer RAFAELI, Robert M. BURK, Marc GLEESON, Mark Richard STEWART, Jonathan DUNN, Alexander James NICHOLLS
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Patent number: 11459351Abstract: Described herein are compositions and methods for the treatment or prevention of ocular surface disorders including meibomian gland dysfunction, blepharitis, dry eye disease and other inflammatory and/or infectious diseases of the anterior surface of the eye(s). Said compositions and methods comprise keratolytic conjugates which demonstrate keratolytic activity, and anti-inflammatory or other desirable activities. Topical administration of said compositions to the eyelid margin or surrounding areas provides therapeutic benefit to patients suffering from ocular surface disorders.Type: GrantFiled: April 5, 2021Date of Patent: October 4, 2022Assignee: AZURA OPHTHALMICS LTD.Inventors: Ian Holmes, Yair Alster, Hila Barash, Charles Bosworth, Omer Rafaeli, Robert M. Burk, Marc Gleeson, Mark Richard Stewart, Jonathan Dunn, Alexander James Nicholls
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Publication number: 20220307514Abstract: A seal includes a mating ring that rotates relative to a carbon primary ring at a seal interface. A buffer gas is provided into the seal and passes from the back of the primary ring to the seal interface. The seal can be used as a separation seal or in combination with another seal.Type: ApplicationFiled: June 15, 2022Publication date: September 29, 2022Inventors: Inderpal Singh Sihra, Isaac Lopez Higuera, Aidaan James Nicholls
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Publication number: 20210222701Abstract: A seal includes a mating ring that rotates relative to a porous carbon primary ring at a seal interface. A buffer gas is provided into the seal and passes from the back of the primary ring to the seal interface. The seal can be used as a separation seal or in combination with another seal.Type: ApplicationFiled: January 20, 2021Publication date: July 22, 2021Inventors: Inderpal Singh Sihra, Isaac Lopez Higuera, Aidaan James Nicholls
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Publication number: 20210217239Abstract: Methods, computer systems and computer programs for generating a virtual representation of an interior space such as a room are provided. Techniques for capturing and normalizing sets of points for polygon mesh generation that utilize augmented reality toolkits are also described.Type: ApplicationFiled: March 26, 2021Publication date: July 15, 2021Inventors: Jonathan SINCLAIR, Robert LEWIS, James NICHOLL, Ciaran HARRIGAN
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Patent number: 10991161Abstract: Methods, computer systems and computer programs for generating a virtual representation of an interior space such as a room are provided. Techniques for capturing and normalizing sets of points for polygon mesh generation that utilize augmented reality toolkits are also described.Type: GrantFiled: May 1, 2019Date of Patent: April 27, 2021Assignee: Signaturize Holdings LtdInventors: Jonathan Sinclair, Robert Lewis, James Nicholl, Ciaran Harrigan
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Publication number: 20190340814Abstract: Methods, computer systems and computer programs for generating a virtual representation of an interior space such as a room are provided. Techniques for capturing and normalizing sets of points for polygon mesh generation that utilize augmented reality toolkits are also described.Type: ApplicationFiled: May 1, 2019Publication date: November 7, 2019Inventors: Jonathan SINCLAIR, Robert LEWIS, James NICHOLL, Ciaran HARRIGAN
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Publication number: 20110201947Abstract: The present invention provides methods and markers for characterizing a subject's, particularly a human subject risk of having cardiovascular disease. The present invention also provides methods of characterizing a subject's risk of developing cardiovascular disease. In another embodiment, the present invention provides methods for characterizing a subject's risk of experiencing a complication of cardiovascular disease or major adverse cardiac event within 1, 3, or 10 years. In another embodiment, the present invention provides a method for determining whether a subject presenting with chest pain is at risk near term of experiencing a heart attack or other major adverse cardiac event. The present methods are especially useful for identifying those subjects who are in need of highly aggressive CVD therapies as well as those subjects who require no therapies targeted at inhibiting or preventing CVD or complications of CVD.Type: ApplicationFiled: March 16, 2009Publication date: August 18, 2011Applicant: THE CLEVELAND CLINIC FOUNDATIONInventors: Stanley L. Hazen, Stephen James Nicholls, Zhiping Wu
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Publication number: 20110104818Abstract: Methods for characterizing a test subject's, particularly a human test subject's, risk of having cardiovascular disease or developing cardiovascular disease are provided. Also provided are methods for characterizing a test subject's risk of experiencing a complication of cardiovascular disease near term. The methods comprise determining levels of one or more carbamylated biomarkers in a bodily fluid of the test subject and/or comparing these levels with a reference value. In certain embodiments, the carbamylated biomarkers are carbamylated albumin, carbamylated fibrinogen, carbamylated immunoglobulin and carbamylated apolipoprotein A. In other embodiments, particularly where the test subject does not have clinical evidence of renal disease, the carbamylated biomarker is free and/or total peptide-bound homocitrulline.Type: ApplicationFiled: August 28, 2008Publication date: May 5, 2011Applicant: The Cleveland Clinic FoundationInventors: Stanley L. Hazen, Zeneng Wang, Stephen James Nicholls, Joe Didonato
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Publication number: 20090208992Abstract: Provided herein are methods for assessing the risk a subject or patient without significant evidence of cardiovascular disease has of experiencing a major adverse cardiac event or requiring revascularization near term. Also provided are methods of determining whether a subject who has experienced a major adverse cardiac event is at risk of experiencing a recurrent major adverse cardiac event near term. The present methods comprise determining the levels of paraoxonase 1 enzymatic activity in the blood, serum, plasma, or any combination of said bodily fluids in the subject.Type: ApplicationFiled: March 14, 2008Publication date: August 20, 2009Applicant: The Cleveland Clinic FoundationInventors: Stanley L. Hazen, Stephen James Nicholls
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Patent number: 6489898Abstract: The present invention provides an alternative means of displaying aircraft flight information traditionally provided by a standalone rate of turn indicator on the aircraft instrumentation panel. The bank angle effective to achieve a rate of turn equal to a desired rate of turn for an aircraft is displayed to the pilot by generating and displaying one or more bank angle markers on the roll scale of an aircraft attitude indicator. The position of the desired rate of turn bank angle markers may be updated continuously as a function of airspeed and other flight parameters. The present invention enables a pilot to perform a coordinated turn at a desired rate of turn without having to reference a separate rate of turn indicator on the instrumentation panel and/or without having to independently calculate the associated bank angle according to any known “rule of thumb” or other estimation method.Type: GrantFiled: November 16, 2000Date of Patent: December 3, 2002Assignee: Honeywell International Inc.Inventor: James Nicholls