Patents by Inventor James Nieman

James Nieman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hemiasterlin analogs
    Patent number: 7579323
    Abstract: This invention provides analogs of hemiasterlin, methods of synthesis of the analogs and use of the analogs as cytotoxic and anti-mitotic agents.
    Type: Grant
    Filed: December 13, 1998
    Date of Patent: August 25, 2009
    Assignee: The University of British Columbia
    Inventors: Raymond Andersen, Edward Piers, James Nieman, John Coleman, Michel Roberge
  • Methods of treating alzheimer's disease
    Publication number: 20060079533
    Abstract: Disclosed are methods for treating Alzheimer's disease, and other diseases, and/or inhibiting beta-secretase enzyme, and/or inhibiting deposition of A beta peptide in a mammal, by use of 3,4-disubstituted piperidinyl compounds of formula (I) wherein the variables R1, R2, R3, R4, Q, W, X, Z, m, and n are defined herein.
    Type: Application
    Filed: March 21, 2002
    Publication date: April 13, 2006
    Inventors: James Nieman, Lawrence Fang, barbara Jagodzinska
  • Antiviral compounds
    Patent number: 6852731
    Abstract: The invention provides a compound of formula I: wherein G, R2, R3, and R4 have any of the values defined in the specification, or a pharmaceutically acceptable salt thereof, as well as processes and intermediates useful for preparing such compounds or salts, and methods of preventing or treating a herpesvirus infection using such compounds or salts.
    Type: Grant
    Filed: January 14, 2003
    Date of Patent: February 8, 2005
    Assignee: Pfizer
    Inventors: Scott D. Larsen, Paul May, Karen Romines, Mark E. Schnute, Steven P. Tanis, James A. Nieman, David John Anderson, Euibong J. Kim, Steven R. Turner
  • ANTIVIRAL COMPOUNDS
    Publication number: 20040242884
    Abstract: The invention provides a compound of formula I: 1
    Type: Application
    Filed: January 14, 2003
    Publication date: December 2, 2004
    Inventors: Scott D. Larsen, Paul May, Karen Romines, Mark E. Schnute, Steven P. Tanis, James A. Nieman, David John Anderson, Euibong J. Kim, Steven R. Turner
  • Process to produce enantiomerically enriched 1-aryl-and 1-heteroaryl-2-aminoethanols
    Publication number: 20040236151
    Abstract: The invention relates to a method of preparing enantiomerically enriched amino alcohols of Formula I 1
    Type: Application
    Filed: March 19, 2004
    Publication date: November 25, 2004
    Applicant: Pfizer, Inc.
    Inventors: Steven P. Tanis, James A. Nieman
  • Heteroaryl-ethanolamine derivatives as antiviral agents
    Publication number: 20040110787
    Abstract: The present invention provides a compound of formula as described herein, which are useful as antiviral agents, in particular, as agents against viruses of the herpes family.
    Type: Application
    Filed: August 27, 2003
    Publication date: June 10, 2004
    Inventors: Mark E. Schnute, Michele M. Cudahy, David John Anderson, Thomas M. Judge, Thomas J. Fleck, Paul Matthew Herrinton, Sajiv K. Nair, Allen Scott, William R. Perrault, Steve P. Tanis, James A. Nieman, Sarah A. Collier, Bruce F. Fleck
  • Pyrroloquinolones as antiviral agents
    Patent number: 6683181
    Abstract: The present invention provides a compound of formula I which is useful as antiviral agents, in particular, as agents against viruses of the herpes family.
    Type: Grant
    Filed: November 5, 2002
    Date of Patent: January 27, 2004
    Assignee: Pharmacia and Upjohn Comapny
    Inventors: Valerie A. Vaillancourt, Sandra Staley, Audris Huang, Richard Allen Nugent, Ke Chen, Sajiv K. Nair, James A. Nieman, Joseph Walter Strohbach
  • Pyridoquinoxaline antivirals
    Publication number: 20030207877
    Abstract: The present invention provides a compound of formula I 1
    Type: Application
    Filed: December 19, 2002
    Publication date: November 6, 2003
    Inventors: Joseph Walter Strohbach, Steven P. Tanis, Malcolm Wilson Moon, James A. Nieman, Thomas J. Beauchamp, Jill M. Northuis, William D. McGhee
  • Pyrroloquinolones as antiviral agents
    Publication number: 20030153561
    Abstract: The present invention provides a compound of formula I 1
    Type: Application
    Filed: November 5, 2002
    Publication date: August 14, 2003
    Inventors: Valerie A. Vaillancourt, Sandra Staley, Audris Huang, Richard Allen Nugent, Ke Chen, Sajiv K. Nair, James A. Nieman, Joseph Walter Strohbach
  • Pyrroloquinolones as antiviral agents
    Patent number: 6525049
    Abstract: The present invention provides a compound of formula I which is useful as antiviral agents, in particular, as agents against viruses of the herpes family.
    Type: Grant
    Filed: June 22, 2001
    Date of Patent: February 25, 2003
    Assignee: Pharmacia & Upjohn Company
    Inventors: Valerie A. Vaillancourt, Sandra Staley, Audris Huang, Richard Allen Nugent, Ke Chen, Sajiv K. Nair, James A. Nieman, Joseph Walter Strohbach
  • Pyrroloquinolones as antiviral agents
    Publication number: 20020055636
    Abstract: The present invention provides a compound of formula I 1
    Type: Application
    Filed: June 22, 2001
    Publication date: May 9, 2002
    Inventors: Valerie A. Vaillancourt, Sandra Staley, Audris Huang, Richard Allen Nugent, Ke Chen, Sajiv K. Nair, James A. Nieman, Joseph W. Strohbach