Patents by Inventor James Noffsinger

James Noffsinger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methodology for colorimetrically determining the concentration of white blood cells in a biological fluid
    Patent number: 5663044
    Abstract: A composition, method and test device for determining the presence of leukocytes, esterase or protease in a test sample are disclosed. The composition comprises an ester which is hydrolyzed in the presence of leukocyte, esterase, or protease to form a reaction product which couples with a diazonium salt to produce a detectable color change. The composition further comprises the salt of an alkaline earth metal which stabilizes the composition during manufacture and prevents the occurrence of false or background color change due to reactivity of the diazonium salt in the absence of leukocyte, esterase or protease.
    Type: Grant
    Filed: February 26, 1996
    Date of Patent: September 2, 1997
    Assignee: Bayer Corporation
    Inventors: James Noffsinger, Michael J. Pugia, Melvin D. Smith