Abstract: A clamp assembly for securing a steering column shroud, comprising: a clamp pin which passes through an opening in the shroud and having a stopper towards one end, a toothed block carried by the clamp pin having a set of rake teeth, the teeth of the block being urged into engagement with a rack of teeth fixed to a support bracket by the stopper when the clamp assembly is in the clamped condition, thereby securing the relative positions of the fixed and moving portions of the steering assembly; and a biasing means that provides a biasing force that acts in an unclamped condition to bias the stopper of the clamp pin away from the moving part to permit the rack of teeth on the block to move clear of the rack of the support bracket, in which a substantial part of the biasing force provided by the biasing means acts upon the clamp pin without passing through the toothed block.

Abstract: A clamp assembly for securing a steering column shroud, comprising: a clamp pin which passes through an opening in the shroud and having a stopper towards one end, a toothed block carried by the clamp pin having a set of rake teeth, the teeth of the block being urged into engagement with a rack of teeth fixed to a support bracket by the stopper when the clamp assembly is in the clamped condition, thereby securing the relative positions of the fixed and moving portions of the steering assembly; and a biasing means that provides a biasing force that acts in an unclamped condition to bias the stopper of the clamp pin away from the moving part to permit the rack of teeth on the block to move clear of the rack of the support bracket, in which a substantial part of the biasing force provided by the biasing means acts upon the clamp pin without passing through the toothed block.

Abstract: We have performed separation of bacterial and cancer cells from peripheral human blood in microfabricated electronic chips by dielectrophoresis. The isolated cells were examined by staining the nuclei with fluorescent dye followed by laser induced fluorescence imaging. We have also released DNA and RNA from the isolated cells electronically and detected specific marker sequences by DNA amplification followed by electronic hybridization to immobilized capture probes. Efforts towards the construction of a “laboratory-on-a-chip” system are presented which involves the selection of DNA probes, dyes, reagents and prototyping of the fully integrated portable instrument.

Abstract: A surgeon selects a volume of interest by placing an untracked “marker” in a patient near an area where an update is desired. During surgery, when an updated CT scan is requested, the CT scanner performs a scan of the patient using a full field of view to take a series of two-dimensional initial images of the patient from a plurality of angularly spaced positions about the patient. The position of the untracked marker is determined by the CT scanner in or more of the initial images. The volume of interest is defined as the position of the untracked marker, plus some margin. The CT scanner then collimates the x-ray source to scan only the volume of interest. The CT scanner then completes the update scan of the volume of interest and updates a previous CT scan(s) to create a fully updated CT image, reducing x-ray exposure of the patient.

Abstract: There is provided a financial transaction payment method and system for processing a transaction conducted using a financial transaction card. The financial transaction card has associated therewith a financial account in a financial institution and one or more transaction criteria. The financial transaction payment system includes a processing unit and an application program for execution on the processing unit. The method includes the step of determining by the application program whether a transaction accesses an installment loan on the financial account based on the one or more transaction criteria.

Abstract: A system for performing molecular biological diagnosis, analysis and multistep and multiplex reactions utilizes a selfaddressable, selfassembling microelectronic system for actively carrying out controlled reactions in microscopic formats. Preferably, a fluidic system flow a sample across an active area of the biochip, increasing diagnostic efficiency. Preferably, the fluidic system includes a flow cell having a window. Pulsed activation of the electrodes of the biochip are advantageously employed with the fluidic system, permitting more complete sampling of the materials within the biological sample. An improved detection system utilizes a preferably coaxially oriented excitation fiber, such as a fiber optic, disposed within a light guide, such as a liquid light guide. In this way, small geometric systems may be fluorescently imaged. A highly automated DNA diagnostic system results.

Abstract: Apparatus and methods are provided for interacting light with particles, including but not limited to biological matter such as cells, in unique and highly useful ways. Optophoresis consists of subjecting particles to various optical forces, especially optical gradient forces, and more particularly moving optical gradient forces, so as to obtain useful results. In biology, this technology represents a practical approach to probing the inner workings of a living cell, preferably without any dyes, labels or other markers. In one aspect, a particle may be characterized by determining its optophoretic constant or signature. For example, a diseased cell has a different optophoretic constant from a healthy cell, thereby providing information, or the basis for sorting. In the event of physical sorting, various forces may be used for separation, including fluidic forces, such as through the use of laminar flow, or optical forces, or mechanical forces, such as through adhesion.