Abstract: An electrical connection assembly of a medical device includes a plurality of electrical contact blocks and a sealing member, which are held within a cavity of a base of the assembly. The sealing member includes a plurality of openings, at least one interior surface surrounding a bore and at least one void. Each electrical contact block extends into a corresponding opening of the sealing member, and a conductive sidewall of each block defines a portion of a perimeter of an area for receiving a lead connector, while the bore of the sealing member forms another portion of the perimeter of the area. The at least one void provides a compressible space in a bulk volume of the sealing member. When the lead is inserted within the area, and a cap is engaged with the base, the at least one interior surface of the sealing member is compressed about the lead.

Abstract: An electrical connection assembly of a medical device includes at least one conductive sidewall mounted in a fixed position to a module base; the sidewall may be electrically coupled to a feedthrough wire. The assembly further includes at least one resilient member to apply a spring force against a connector element of a lead connector when the connector element is positioned adjacent to the conductive sidewall. The spring force of the resilient member causes electrical coupling between the connector element and the conductive sidewall.

Abstract: An electrical connection assembly of a medical device includes at least one conductive sidewall mounted in a fixed position to a module base; the sidewall may be electrically coupled to a feedthrough wire. The assembly further includes at least one resilient member to apply a spring force against a connector element of a lead connector when the connector element is positioned adjacent to the conductive sidewall. The spring force of the resilient member causes electrical coupling between the connector element and the conductive sidewall.

Abstract: An implantable drug infusion pump for delivering drug therapy is made more reliable and its performance improved by monitoring drug pump temperature. Monitoring pump temperature can also provide for temperature-related drug therapy modification. A pump temperature sensor is read by the infusion pump's microprocessor. Pump temperature data is stored in pump memory for later access by a remote controller. A simple thermistor or semiconductor temperature sensor can provide fast and reliable temperature monitoring of the pump and/or of a patient by reading the temperature sensor's value and calculating a temperature therefrom.

Abstract: A system for monitoring an implantable medical device. The system includes an implantable therapeutic substance delivery device for delivering a therapeutic substance, along with a temperature sensor and an indicator device. The delivery device includes a housing maintaining a reservoir for containing the therapeutic substance. Further, the delivery device includes a fill port assembly having a port chamber in fluid communication with the reservoir and including a septum fluidly sealing the chamber. The temperature sensor is associated with the fill port assembly. Finally, the indicator device is adapted to indicate presence of a needle within the port chamber based upon information from the temperature sensor.

Abstract: A medical device known as an implantable therapeutic substance infusion device is configured for implanting in humans to deliver a therapeutic substance such as pharmaceutical compositions, genetic materials, and biologics to treat a variety of medical conditions such as pain, spastisity, cancer, and many other conditions. The therapeutic substance infusion device has a piston pump with an anti-cavitation valve to reduce gas formation, increase accuracy, improve efficiency and has many other improvements. The therapeutic substance infusion device has a housing, a therapeutic substance reservoir, a power source carried in the housing, electronics, a piston pump, an inlet valve, and anti-cavitation valve. The piston pump is configured for pumping therapeutic substance from the therapeutic substance reservoir through an infusion port at a programmed rate.

Abstract: Implantable medical electrical leads, kits, systems and methods of use thereof for electrically stimulating the spinal cord with a plurality of electric stimulation leads. Directional stimulation electrodes are disposed along the distal end portions of the leads to form an electrode array in the epidural space of a patient with at least first, second and third directional stimulation electrodes being oriented at determined angular orientations relative to the spinal cord or each other. The stimulation electrodes may be programmed to create a tripole in which at least the first, second and third directional stimulation electrodes are active.

Abstract: A flow regulator (508, 508?, 508?, 508??) may be used in a drug delivery system. The regulator has an adjustable flow rate. A spring 528 that is adjustable to control the flow rate is controlled by either a motor (560, 560?), magnetic actuator (561) or ultrasonic actuator (563).

Abstract: A miniature drug delivery pump utilizes a shape memory Ni-Ti alloy. A flow restrictor is provided and the pump is refillable.

Abstract: A medical lead is configured to be implanted into a patient's body and comprises a lead body, and an electrode coupled to the lead body. The electrode comprises a first section configured to contact the patient's body, and a second section electrically coupled to the first section and configured to be capacitively coupled to the patient's body.

Abstract: A medical lead is configured to be implanted into a patient's body and comprises a lead body, and an electrode coupled to the lead body. The electrode comprises a first section configured to contact the patient's body, and a second section capacitively coupled to the first section and configured to be electrically coupled to the patient's body.

Abstract: Low profile inlet valve embodiments for a piston pump therapeutic substance infusion device are disclosed that reduce dead volume, occupies little residential space, operates rapidly, and have many other improvements. The therapeutic substance infusion device has a housing, a therapeutic substance reservoir, a power source carried in the housing, electronics, a piston pump, and an inlet valve. The piston pump is configured for pumping therapeutic substance from the therapeutic substance reservoir through an infusion port at a programmed rate. The inlet valve is in fluid communication with a reservoir outlet to control the flow of therapeutic substance into the piston pump. The inlet valve has a substantially coplanar valve surface and valve spring. Many embodiments of the low profile inlet valve and its methods of operation are possible.

Abstract: An implantable neurostimulation lead kit adapted for tripolar electric simulation and/or field steering using percutaneously implantable electric stimulation leads. The kit includes three electric stimulation leads that are adapted to provide an electrode array defining, for example, a plurality of electrode sets that may be used to provide tripolar stimulation and/or electric field steering. A method of electrically stimulating the spinal cord is also described.

Abstract: An implantable lead has a lead body construction designed to accommodate loading forces exerted on the lead body during patient movement. The lead body may be sufficiently stretchable to resist forces that could otherwise cause lead failure, axial migration of the electrodes, anchor damage, or tissue damage. Increasing stretchability of a lead body can also increase the vulnerability of the lead body to flex fatigue, buckling fatigue, kinking, and crush. Therefore, the lead described herein includes conductors that comprise coiled wires positioned substantially parallel to a center axis of the lead. The conductors described herein may be coiled around fibers that limit the axial stiffness of the coiled wires to ensure full recovery from axial loading.

Abstract: An implantable lead has a lead body construction designed to accommodate loading forces exerted on the lead body during patient movement. The lead body described herein is sufficiently stretchable to resist forces that could otherwise cause lead failure, axial migration of the electrodes, anchor damage, or tissue damage. The lead body may include a variety of features that reduce the axial stiffness of the lead without significantly impacting the operation and structural integrity of lead components, such as electrodes, conductors and insulators.

Abstract: An implantable lead has a lead body construction designed to accommodate loading forces exerted on the lead body during patient movement. The lead body may be sufficiently stretchable to resist forces that could otherwise cause lead failure, axial migration of the electrodes, anchor damage, or tissue damage. Increasing stretchability of a lead body can also increase the vulnerability of the lead body to flex fatigue, buckling fatigue, kinking, and crush. Therefore, the lead described herein includes a reinforcement to create a lead body that is resistant to flex fatigue, buckling fatigue, kinking and crush.

Abstract: An implantable lead has a lead body construction designed to accommodate loading forces exerted on the lead body during patient movement. The lead body may be sufficiently stretchable to resist forces that could otherwise cause lead failure, axial migration of the electrodes, anchor damage, or tissue damage. Increasing stretchability of a lead body can also increase the vulnerability of the lead body to flex fatigue, buckling fatigue, kinking, and crush. Therefore, the lead described herein includes a coiled wire embedded between a first insulative layer and a second insulative layer of an outer jacket of the lead body to improve column stiffness and kink resistance.

Abstract: A connector and method of medical tubing is disclosed. The connector defines a fluid passageway, and the connector includes a first end, a first intermediate portion, a middle portion, a second intermediate portion, and a second end. The middle portion is located between the first intermediate portion and the second intermediate portion, and the first end is adapted to fit inside a proximal connector-receiving portion, and the second end is adapted to fit inside a distal connector-receiving portion. The connector includes at least a first protrusion and a second protrusion projecting from the connector, wherein a first protrusion is located between the first end and the first intermediate portion, and the second protrusion is located between the second intermediate portion and the second end.

Abstract: A connector and method of medical tubing is disclosed. The connector defines a fluid passageway, and the connector includes a first end, a first intermediate portion, a middle portion, a second intermediate portion, and a second end. The middle portion is located between the first intermediate portion and the second intermediate portion, and the first end is adapted to fit inside a proximal connector-receiving portion, and the second end is adapted to fit inside a distal connector-receiving portion. The connector includes at least a first protrusion and a second protrusion projecting from the connector, wherein a first protrusion is located between the first end and the first intermediate portion, and the second protrusion is located between the second intermediate portion and the second end.

Abstract: A flow regulator (19, 208, 308, 408) may be used in a drug delivery system 10. The regulator includes a chamber that is divided by a diaphragm (111, 211, 311, 411) into a first and second subchamber. A third subchamber is in fluid communication with the first subchamber. A valve (26, 217, 317, 417) is operatively connected to the diaphragm, wherein pressure differences between the first subchamber and second subchamber result in movement of the diaphragm and movement of the diaphragm controls operation of the valve. A flow restrictor (116, 216, 316, 416) is in fluid communication between the first and second subchambers. Flow of a drug (11, 101) is thereby regulated.