Patents by Inventor James Onslow

James Onslow has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230143960
    Abstract: A cartridge can comprise a first elastomeric membrane and a second elastomeric membrane, and portions of the elastomeric membranes which are sealed to each other can circumscribe unsealed portions of the membranes. In a resting state, the unsealed portion of the first elastomeric membrane abuts or is proximate to the unsealed portion of the second elastomeric membrane. One or more reagents can be injected between the unsealed portions of the first and second elastomeric membranes to push the unsealed portions apart from each other in this region of the membranes. The unsealed portions can be sequentially pushed apart in downstream regions to form a channel between the elastomeric membranes. Positively displaced fluid pushes the unsealed membrane portions apart to a volume that conforms to the volume of the fluid to minimize or prevent dead volume in the channel and thus minimize or prevent air bubbles in the fluid.
    Type: Application
    Filed: November 7, 2022
    Publication date: May 11, 2023
    Inventors: William LAFFERTY, Mikhail Bashtanov, Peter Crossley, Abi Graham, Gary Jepps, Richard Lintern, Stuart Lowe, Yang Lu, James Onslow, Neil Pollock, Sebastian Rammensee, Richard Janse van Rensburg, Steve Wakefield, Peter Eugster
  • Publication number: 20190022637
    Abstract: A cartridge can comprise a first elastomeric membrane and a second elastomeric membrane, and portions of the elastomeric membranes which are sealed to each other can circumscribe unsealed portions of the membranes. In a resting state, the unsealed portion of the first elastomeric membrane abuts or is proximate to the unsealed portion of the second elastomeric membrane. One or more reagents can be injected between the unsealed portions of the first and second elastomeric membranes to push the unsealed portions apart from each other in this region of the membranes. The unsealed portions can be sequentially pushed apart in downstream regions to form a channel between the elastomeric membranes. Positively displaced fluid pushes the unsealed membrane portions apart to a volume that conforms to the volume of the fluid to minimize or prevent dead volume in the channel and thus minimize or prevent air bubbles in the fluid.
    Type: Application
    Filed: September 2, 2016
    Publication date: January 24, 2019
    Inventors: William M. Lafferty, Mikhail Bashtanov, Peter Crossley, Abi Graham, Gary Jepps, Richard Lintern, Stuart Lowe, Yang Lu, James Onslow, Neil Pollock, Sebastian Rammensee, Richard Janse van Rensburg, Steve Wakefield, Peter Eugster
  • Publication number: 20100261179
    Abstract: The application provides sample preparation devices and analyses. The devices and analyzes allow for the rapid preparation and analysis of samples using a variety of techniques, including PCR, by even unskilled users.
    Type: Application
    Filed: October 17, 2008
    Publication date: October 14, 2010
    Inventors: Jason Betley, Barry Boyes, John Walter Czajka, Michael Roy Fairs, Colin Fewster, Thomas David Ford, Douglas Jason Green, Piers Sebastian Harding, Gary Stephen Howard, Jay Lewington, William Richard Mawer, Catherine Mills, James Onslow, Carmelo Volpe