Abstract: A rotary genderless valve (500) having a body (502) having a body hole (524); a body cover (510) for attaching to the body, the body cover comprising a cover hole (522) and optionally comprising alignment holes (514); a handle (504), wherein the handle moves from a closed position and an open position actuated by a rotary motion; and a rotary slide (528) attached to the handle capable of partial rotation, wherein the rotary slide has an elastomeric slide which comprises a rotary slide hole (526); and, optionally, a second genderless valve having a second rotary slide and rotary slide hole, wherein the rotary slide hole and the second rotary slide hole are in fluid communication with one another.

Abstract: The present invention is to a dripless fluid coupling device (a dripless connector) that can be used to driplessly connect and disconnect devices or assemblies to and from each other in a sterile manner. The dripless fluid coupling device of the present invention is easy to manufacture using known materials and methods; easy to use, requiring only a clamping device to connect and disconnect; sterilizable and relatively inexpensive compared to available prior art devices.

Abstract: The present invention is for a magnetized filter holder.

Abstract: A fluid transfer device comprising: a housing; a core positioned in the housing for relative movement with the housing, the core having a bore having an inlet and an outlet spaced from the inlet, and first and second gate-receiving regions spaced from the inlet and the outlet; and an actuator operatively connected in the device to cause relative movement between said core and said housing. Also disclosed is a method of creating an aseptic connection using the fluid transfer device.

Abstract: The present invention is for a magnetized filter holder.

Abstract: An apparatus for treating a biological fluid, comprising a plurality of filtration devices. In some embodiments, each of the plurality of filtration devices comprising at least one inlet and at least one outlet; and a first insert plate and a second insert plate opposite the first insert plate, wherein the plurality of filtration devices is disposed therebetween. In some embodiments, each filtration device has a vent port. A manifold for each of the inlets, outlets, and vent ports is optionally fluidly connected. In another embodiment, hose barb connectors or the like may be protected from damage and/or exposure by being recessed in the device or positioned at a periphery of the device. Embodiments include apparatus and methods to achieve dripless connect/disconnect and to reduce the number of sterile-to-sterile connections.

Abstract: An incubation chamber that may be provided in modular form in order to provide flexibility in flow rate and/or residence time of a product stream is disclosed. Assemblies including such incubation chambers for purification of biomolecules are also disclosed, as are methods for biomolecule purification, and in particular, methods for virus inactivation in an incubation chamber or in a plurality of incubation chambers arranged in series.