Patents by Inventor James P. Clarkin
James P. Clarkin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10466165Abstract: An improved optical flow cell adapted for use in a flow cytometer for differentiating formed bodies (e.g., blood cells) in liquid suspensions. Preferably manufactured by assembling, aligning, and optically joining at least two elements made from transparent material, the improved flow cell has a seamless internal flow channel of preferably non-circular cross-section in a cylindrical first element through which prepared samples can be metered and an independent second element having an external envelope suited to acquisition of optical parameters from formed bodies in such suspensions, the second element being conforming and alignable to the first element so that non-axisymmetric refractive effects on optical characterizing parameters of formed bodies passing through the flow channel in the first element may be minimized before the two elements are optically joined and fixed in working spatial relationship.Type: GrantFiled: September 25, 2017Date of Patent: November 5, 2019Assignee: Beckman Coulter, Inc.Inventors: Marshall Donnie Graham, William Gerry Graham, James P. Clarkin, Mark A. Wells, Jose M. Cano, Carlos Alberto Arboleda, Armando J. Sanchez
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Publication number: 20180188154Abstract: An improved optical flow cell adapted for use in a flow cytometer for differentiating formed bodies (e.g., blood cells) in liquid suspensions. Preferably manufactured by assembling, aligning, and optically joining at least two elements made from transparent material, the improved flow cell has a seamless internal flow channel of preferably non-circular cross-section in a cylindrical first element through which prepared samples can be metered and an independent second element having an external envelope suited to acquisition of optical parameters from formed bodies in such suspensions, the second element being conforming and alignable to the first element so that non-axisymmetric refractive effects on optical characterizing parameters of formed bodies passing through the flow channel in the first element may be minimized before the two elements are optically joined and fixed in working spatial relationship.Type: ApplicationFiled: September 25, 2017Publication date: July 5, 2018Applicant: Beckman Coulter, Inc.Inventors: Marshall Donnie Graham, William Gerry Graham, James P. Clarkin, Mark A. Wells, Jose M. Cano, Carlos Alberto Arboleda, Armando J. Sanchez
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Patent number: 9772274Abstract: An improved optical flow cell adapted for use in a flow cytometer for differentiating formed bodies (e.g., blood cells) in liquid suspensions. Preferably manufactured by assembling, aligning, and optically joining at least two elements made from transparent material, the improved flow cell has a seamless internal flow channel of preferably non-circular cross-section in a cylindrical first element through which prepared samples can be metered and an independent second element having an external envelope suited to acquisition of optical parameters from formed bodies in such suspensions, the second element being conforming and alignable to the first element so that non-axisymmetric refractive effects on optical characterizing parameters of formed bodies passing through the flow channel in the first element may be minimized before the two elements are optically joined and fixed in working spatial relationship.Type: GrantFiled: March 14, 2014Date of Patent: September 26, 2017Assignee: Beckman Coulter, Inc.Inventors: Marshall Donnie Graham, William Gerry Graham, James P. Clarkin, Mark A. Wells, Jose M. Cano, Carlos Alberto Arboleda, Armando J. Sanchez
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Patent number: 9575261Abstract: An embedded optical fiber termination device includes a fiber holder with an inner bore and an outer surface. The inner bore is configured to receive a length of optical fiber therein. A removable armature is positioned about a portion of the outer surface of the fiber holder and is removably positioned around a portion of the fiber holder. A composite structure and a method of using the embedded device are also provided.Type: GrantFiled: March 18, 2016Date of Patent: February 21, 2017Assignee: Molex, LLCInventors: Malcolm H. Hodge, James P. Clarkin
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Publication number: 20160202426Abstract: An embedded optical fiber termination device includes a fiber holder with an inner bore and an outer surface. The inner bore is configured to receive a length of optical fiber therein. A removable armature is positioned about a portion of the outer surface of the fiber holder and is removably positioned around a portion of the fiber holder. A composite structure and a method of using the embedded device are also provided.Type: ApplicationFiled: March 18, 2016Publication date: July 14, 2016Applicant: Molex, LLCInventors: Malcolm H. Hodge, James P. Clarkin
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Patent number: 9323021Abstract: An embedded optical fiber termination device includes a fiber holder with an inner bore and an outer surface. The inner bore is configured to receive a length of optical fiber therein. A removable armature is positioned about a portion of the outer surface of the fiber holder and is removably positioned around a portion of the fiber holder. A composite structure and a method of using the embedded device are also provided.Type: GrantFiled: March 23, 2011Date of Patent: April 26, 2016Assignee: Molex, LLCInventors: Malcolm H. Hodge, James P. Clarkin
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Publication number: 20160011098Abstract: An improved optical flow cell adapted for use in a flow cytometer for differentiating formed bodies (e.g., blood cells) in liquid suspensions. Preferably manufactured by assembling, aligning, and optically joining at least two elements made from transparent material, the improved flow cell has a seamless internal flow channel of preferably non-circular cross-section in a cylindrical first element through which prepared samples can be metered and an independent second element having an external envelope suited to acquisition of optical parameters from formed bodies in such suspensions, the second element being conforming and alignable to the first element so that non-axisymmetric refractive effects on optical characterizing parameters of formed bodies passing through the flow channel in the first element may be minimized before the two elements are optically joined and fixed in working spatial relationship.Type: ApplicationFiled: March 14, 2014Publication date: January 14, 2016Inventors: Marshall Donnie GRAHAM, William Gerry GRAHAM, James P. CLARKIN, Mark A. WELLS, Jose M. CANO, Carlos Alberto ARBOLEDA, Armando J. SANCHEZ
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Publication number: 20130101259Abstract: An embedded optical fiber termination device includes a fiber holder with an inner bore and an outer surface. The inner bore is configured to receive a length of optical fiber therein. A removable armature is positioned about a portion of the outer surface of the fiber holder and is removably positioned around a portion of the fiber holder. A composite structure and a method of using the embedded device are also provided.Type: ApplicationFiled: March 23, 2011Publication date: April 25, 2013Applicant: MOLEX INCORPORATEDInventors: Malcolm H. Hodge, James P. Clarkin
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Patent number: 8216980Abstract: Micro channel array devices drawn from a bulk preform having an array of components to reduce the cross section. The reduced cross section fiber like structure is cut to produce individual arrays of small scale. End caps are drawn and optionally micro machined. The end caps are used to provide input and output ports and other structures for use with the micro channel arrays. A micro channel array may be used with different end caps for analysis and may form a lab on a chip or a component thereof.Type: GrantFiled: August 8, 2005Date of Patent: July 10, 2012Assignee: Polymicro Technologies LLCInventors: James P. Clarkin, Gary W. Nelson, Robert J. Macomber
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Patent number: 8189187Abstract: An improved optical flow cell adapted for use in a flow cytometer for differentiating formed bodies (e.g., blood cells). Manufactured from a monolithic transparent material, the improved flow cell has an internal flow channel of polygonal transverse cross-section through which prepared samples can be metered and an external envelope suited to acquisition of optical parameters from formed bodies in such samples. Preferably, such flow cell is formed by a glass-drawing process in which a relatively large glass preform having a rectilinear internal channel of a desired polygonal cross-sectional shape is heated and drawn to achieve a desired cross-sectional area of reduced size. Also disclosed are preferred methods for differentiating formed bodies using the flow cell of the invention.Type: GrantFiled: November 13, 2009Date of Patent: May 29, 2012Assignee: Beckman Coulter, Inc.Inventors: Marshall Donnie Graham, William Gerry Graham, James P. Clarkin, Mark A. Wells, Jose M. Cano, Carlos Alberto Arboleda, Armando Jose Sanchez
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Publication number: 20100290041Abstract: An improved optical flow cell adapted for use in a flow cytometer for differentiating formed bodies (e.g., blood cells). Manufactured from a monolithic transparent material, the improved flow cell has an internal flow channel of polygonal transverse cross-section through which prepared samples can be metered and an external envelope suited to acquisition of optical parameters from formed bodies in such samples. Preferably, such flow cell is formed by a glass-drawing process in which a relatively large glass preform having a rectilinear internal channel of a desired polygonal cross-sectional shape is heated and drawn to achieve a desired cross-sectional area of reduced size. Also disclosed are preferred methods for differentiating formed bodies using the flow cell of the invention.Type: ApplicationFiled: November 13, 2009Publication date: November 18, 2010Applicant: Beckman Coulter, Inc.Inventors: Marshall Donnie GRAHAM, William Gerry GRAHAM, James P. CLARKIN, Mark A. WELLS, Jose M. CANO, Carlos Alberto ARBOLEDA, Armando Jose SANCHEZ
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Patent number: 6883975Abstract: The invention includes a ferrule having a layer of material on an inner surface of a hole therein which is selected to be preferentially softenable relative to the bulk material of the ferrule. The ferrule according to the present invention can be fused to optical fibers, capillaries and the like while reducing deformation of the fused component and the ferrule.Type: GrantFiled: July 24, 2001Date of Patent: April 26, 2005Assignee: Polymicro Technologies, Inc.Inventors: James P. Clarkin, John Shannon, Michael Swengler
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Patent number: 6752537Abstract: The invention includes a ferrule having a layer of material on an inner surface of a hole therein which is selected to be preferentially softenable relative to the bulk material of the ferrule. The ferrule according to the present invention can be fused to optical fibers, capillaries and the like while reducing deformation of the fused component and the ferrule. A fiber Bragg grating device and a flow cell device are also provided.Type: GrantFiled: July 24, 2002Date of Patent: June 22, 2004Assignee: Polymicro Technologies, LLCInventors: James P Clarkin, John Shannon, Michael Swengler
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Publication number: 20030095752Abstract: The invention includes a ferrule having a layer of material on an inner surface of a hole therein which is selected to be preferentially softenable relative to the bulk material of the ferrule. The ferrule according to the present invention can be fused to optical fibers, capillaries and the like while reducing deformation of the fused component and the ferrule. A fiber Bragg grating device and a flow cell device are also provided.Type: ApplicationFiled: July 24, 2002Publication date: May 22, 2003Inventors: James P. Clarkin, John Shannon, Michael Swengler
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Patent number: 6546174Abstract: An extended length side emitting cable is disclosed. The cable includes transmitting and side emitting fibers. As light proceeds along the side emitting fibers, it decreases in intensity and in color quality. The transmitting fibers are coupled into the side emitting fibers to refresh the light. In this manner the cable maintains increased uniformity of color and intensity along its length.Type: GrantFiled: January 9, 2001Date of Patent: April 8, 2003Assignee: Polymicro Technologies, LLC.Inventor: James P. Clarkin
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Publication number: 20020110332Abstract: The invention includes a ferrule having a layer of material on an inner surface of a hole therein which is selected to be preferentially softenable relative to the bulk material of the ferrule. The ferrule according to the present invention can be fused to optical fibers, capillaries and the like while reducing deformation of the fused component and the ferrule.Type: ApplicationFiled: July 24, 2001Publication date: August 15, 2002Applicant: POLYMICRO TECHNOLOGIES, INC.Inventors: James P. Clarkin, John Shannon, Michael Swengler
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Publication number: 20020090182Abstract: An extended length side emitting cable is disclosed. The cable includes transmitting and side emitting fibers. As light proceeds along the side emitting fibers, it decreases in intensity and in color quality. The transmitting fibers are coupled into the side emitting fibers to refresh the light. In this manner the cable maintains increased uniformity of color and intensity along its length.Type: ApplicationFiled: January 9, 2001Publication date: July 11, 2002Inventor: James P. Clarkin
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Publication number: 20020072111Abstract: Micro channel array devices drawn from a bulk preform having an array of components to reduce the cross section. The reduced cross section fiber like structure is cut to produce individual arrays of small scale. End caps are drawn and optionally micro machined. The end caps are used to provide input and output ports and other structures for use with the micro channel arrays. A micro channel array may be used with different end caps for analysis and may form a lab on a chip or a component thereof.Type: ApplicationFiled: January 30, 2001Publication date: June 13, 2002Inventors: James P. Clarkin, Gary W. Nelson, Robert J. Macomber